JCN Calendar of Events
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - November 7, 2016 Category: Neurology Tags: & lt;I gt;JCN lt;/I gt; Calendar of Events Source Type: research
Authors Response to Letter to the Editor
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - November 7, 2016 Category: Neurology Authors: Zeidman, L. A., Kondziella, D., Stone, J. L. Tags: Other Source Type: research
Sleep Apnea in Patients With Rett Syndrome: Roles for Polysomnography and Adenotonsillectomy
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - November 7, 2016 Category: Neurology Authors: Bassett, E., Heinle, R., Johnston, D. Tags: Correspondence Source Type: research
Lacosamide in Lennox-Gastaut Syndrome? Caution Is Still Needed
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - November 7, 2016 Category: Neurology Authors: Ferlazzo, E., Gasparini, S., Sueri, C., Cianci, V., Aguglia, U. Tags: Correspondence Source Type: research
Letter to the Editor: Regarding "Neurologic Complications Caused by Epstein-Barr Virus in Pediatric Patients"
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - November 7, 2016 Category: Neurology Authors: Dogan, M., Dogan, D. G. Tags: Correspondence Source Type: research
Intermediate Type of Obstetric Brachial Plexus Palsy
Data of 829 infants with obstetric brachial plexus palsy were reviewed to identify any cases that could not be fitted into the any of the well-known types of palsy. These unusual cases were studied in detail with regard to clinical presentation and electrophysiological findings as well as management and spontaneous motor recovery. Erb’s, extended Erb’s, and total palsies were seen in 42.8%, 28.8%, and 28.0% of cases, respectively. Three cases (0.4%) did not fit into any of the classic types. One case had bilateral palsy, and the remaining 2 cases had unilateral palsy. All affected limbs presented with "abducted...
Source: Journal of Child Neurology - November 7, 2016 Category: Neurology Authors: El-Sayed, A. A. F. Tags: Original Articles Source Type: research
Predictors of Neurological Outcome of Tuberculous Meningitis in Childhood: A Prospective Cohort Study From a Developing Country
Conclusions:
Despite the high in-hospital mortality, in resource-constraint settings, the survivors showed remarkable improvement, with two-thirds returning to a normal functional status at 6 months’ follow-up. (Source: Journal of Child Neurology)
Source: Journal of Child Neurology - November 7, 2016 Category: Neurology Authors: Dhawan, S. R., Gupta, A., Singhi, P., Sankhyan, N., Malhi, P., Khandelwal, N. Tags: Original Articles Source Type: research
Cognitive Development in Infantile-Onset Pompe Disease Under Very Early Enzyme Replacement Therapy
Most patients with infantile-onset Pompe disease die in early infancy before beginning enzyme replacement therapy, which has made it difficult to evaluate the impact of Pompe disease on cognitive development. Patients with infantile-onset Pompe disease can survive with enzyme replacement therapy, and physicians can evaluate cognitive development in these patients. We established an effective newborn screening program with quick clinical diagnostic criteria. Cognitive and motor development were evaluated using the Bayley Scales of Infant and Toddler Development–Third Edition at 6, 12, and 24 months of age. The patient...
Source: Journal of Child Neurology - November 7, 2016 Category: Neurology Authors: Lai, C.-J., Hsu, T.-R., Yang, C.-F., Chen, S.-J., Chuang, Y.-C., Niu, D.-M. Tags: Original Articles Source Type: research
The Implications of Brain MRI in Autism Spectrum Disorder
Our objective was to describe the types of providers who refer children with autism spectrum disorder (ASD) for brain magnetic resonance imaging (MRI), the referral reason, and MRI results. The most common referral reasons were autism spectrum disorder with seizures (33.7%), autism spectrum disorder alone (26.3%), and autism spectrum disorder with abnormal neurologic examination or preexisting finding (24%). Neurology (62.5%), general pediatric (22.3%), and developmental/behavioral practitioners (8.9%) referred the most patients. The prevalence of definite pathology was highest in children referred for autism spectrum diso...
Source: Journal of Child Neurology - November 7, 2016 Category: Neurology Authors: Cooper, A. S., Friedlaender, E., Levy, S. E., Shekdar, K. V., Bradford, A. B., Wells, K. E., Mollen, C. Tags: Original Articles Source Type: research
Repeat Concussion and Recovery Time in a Primary Care Pediatric Office
The authors enrolled 95 patients in a primary care office who presented with a concussion. Of these patients, 63% were sport concussions. The authors matched 90 of these patients to children in the authors’ practice presenting for sports physicals or regular check-ups in the following demographics: age, participating in a particular sport, having attention-deficit disorder/attention-deficit hyperactivity disorder, gender, and grade. The authors found the odds of recurrent concussions, in a primary care pediatric office, to be a ratio of 2.909 (95% confidence interval 1.228-7.287). Recovery time for repeat concussion ...
Source: Journal of Child Neurology - November 7, 2016 Category: Neurology Authors: Taubman, B., McHugh, J., Rosen, F., Elci, O. U. Tags: Original Articles Source Type: research
Barriers to Seizure Management in Schools: Perceptions of School Nurses
The purpose of this study was to assess school nurses’ perceptions of barriers to optimal management of seizures in schools. Eighty-three school nurses completed an electronic survey. Most agreed they felt confident they could identify a seizure (97.6%), give rectal diazepam (83.8%), and handle cluster seizures (67.1%), but fewer were confident they could give intranasal midazolam (63.3%), had specific information about a student’s seizures (56.6%), or could swipe a vagus nerve stimulator magnet (47.4%). Nurses were more likely to be available at the time of a seizure in rural (17/20) (85%) versus suburban (21/...
Source: Journal of Child Neurology - November 7, 2016 Category: Neurology Authors: Terry, D., Patel, A. D., Cohen, D. M., Scherzer, D., Kline, J. Tags: Original Articles Source Type: research
Recurrent GNAO1 Mutations Associated With Developmental Delay and a Movement Disorder
In 2 unrelated patients with axial hypotonia, developmental delay and a hyperkinetic movement disorder, a missense mutation was found in codon 209 of the GNAO1 gene. From the still scarce literature on GNAO1 mutations, a clear genotype-phenotype correlation emerged. From the 26 patients reported thus far, 12 patients had epileptic encephalopathy, and 14 had a developmental delay and a hyperkinetic movement disorder. All but 1 of the latter patients had missense mutations in GNAO1 codon 209 or 246, which thus appear to be mutation hotspots. At least 2 sibling pairs showed that the recurrence risk after 1 affected child with...
Source: Journal of Child Neurology - November 7, 2016 Category: Neurology Authors: Menke, L. A., Engelen, M., Alders, M., Odekerken, V. J. J., Baas, F., Cobben, J. M. Tags: Original Articles Source Type: research
Habituation as Parameter for Prediction of Mental Development in Healthy Preterm Infants: An Electrophysiological Pilot Study
The aim of this prospective pilot study was to evaluate the predictive value of discrimination and habituation, which was measured by mismatch negativity in 17 healthy very preterm (mean gestational age 27.4 weeks; range 25.0-31.3) and 16 term (mean gestational age 40.3 weeks; range 37.9-41.7) born infants at term equivalent age. Developmental outcome was measured by Bayley Scales of Infant Development–I in 13 preterm and 13 term-born children at a mean age of 21.7 months (±2.18) and 18.5 months (±1.9), respectively. No differences in amplitude and latency of the mismatch negativity were found between b...
Source: Journal of Child Neurology - November 7, 2016 Category: Neurology Authors: Weber, P., Depoorter, A., Hetzel, P., Lemola, S. Tags: Original Articles Source Type: research
Description and Contribution of Brain Magnetic Resonance Imaging in Nontraumatic Critically Ill Children
Conclusion:
Brain MRI is one component of neuromonitoring, and this study suggests a substantial diagnostic contribution, although its therapeutic impact appears limited to specific diagnoses. (Source: Journal of Child Neurology)
Source: Journal of Child Neurology - November 7, 2016 Category: Neurology Authors: Mortamet, G., Kossorotoff, M., Baptiste, A., Boddaert, N., Castelle, M., Hubert, P., Lesage, F., Renolleau, S., Oualha, M. Tags: Original Articles Source Type: research
Bilirubin-Induced Neurological Dysfunction: A Clinico-Radiological-Neurophysiological Correlation in 30 Consecutive Children
The clinical expression of bilirubin-induced neurological dysfunction varies according to severity and location of the disease. Definitions have been proposed to describe different bilirubin-induced neurological dysfunction subtypes. Our objective was to describe the severity and clinico-radiological-neurophysiological correlation in 30 consecutive children with bilirubin-induced neurological dysfunction seen over a period of 5 years. Thirty children exposed to acute neonatal bilirubin encephalopathy were included in the study. The mean peak total serum bilirubin level was 625 μmol/L (range 480-900 μmol/L). Acoustic ...
Source: Journal of Child Neurology - November 7, 2016 Category: Neurology Authors: van Toorn, R., Brink, P., Smith, J., Ackermann, C., Solomons, R. Tags: Original Articles Source Type: research
