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Specialty: Neurology
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Total 18 results found since Jan 2013.

Dysphagia-related acute stroke complications: A retrospective observational cohort study
Dysphagia, or impaired swallowing, is reported to affect between 8.1% and 45.3% of patients following stroke.1 Dysphagia is associated with longer length of stay (LOS) in acute hospital, increased healthcare costs, and greater long-term institutionalisation.2,3 Aspiration pneumonia mediates a significant proportion of this deleterious association and, in its own right, is associated with increased length of stay in hospital,4 poorer post-stroke functioning,5,6 and increased mortality.7
Source: Journal of Stroke and Cerebrovascular Diseases - April 12, 2023 Category: Neurology Authors: Verity E. Bond, Sebastian Doeltgen, Timothy Kleinig, Joanne Murray Source Type: research

Speed up discharge planning at the acute stroke unit: A development and external validation study for the early prediction of discharge home
ConclusionsThe developed decision tree shows acceptable external validity in predicting discharge home in a heterogeneous sample of stroke patients, only based on the patient's actual ADL performance <48 h poststroke. Importantly, discharge was safe, i.e., no re-hospitalization was registered. The tree's application to speed up discharge planning should now be further evaluated.
Source: Frontiers in Neurology - September 16, 2022 Category: Neurology Source Type: research

Cost-Effectiveness of Low-Dose Compared to Standard-Dose Alteplase for Acute Ischemic Stroke in China: A Within-Trial Economic Evaluation of the ENCHANTED Study
Conclusions: This health economic evaluation alongside the ENCHANTED indicates that the use of low-dose alteplase does not save overall healthcare costs nor lead to a gain in QALYs in the management of Chinese patients with AIS compared to the use of standard dose. There is little justification on economic grounds to shift from standard-of-care thrombolysis in AIS.Cerebrovasc Dis
Source: Cerebrovascular Diseases - August 31, 2022 Category: Neurology Source Type: research

Impaired Nutritional Condition After Stroke From the Hyperacute to the Chronic Phase: A Systematic Review and Meta-Analysis
ConclusionINC and malnutrition are highly prevalent in all stages of stroke care. Since malnutrition has been shown to negatively affect clinical outcomes, mortality, and overall healthcare expenditure in stroke survivors, it is essential to examine and monitor the nutritional status of stroke patients throughout their care journey to guide and plan, timely nutritional support and dietary modification.
Source: Frontiers in Neurology - February 1, 2022 Category: Neurology Source Type: research

Association Between Weight Loss and Activities of Daily Living in Obese and Overweight Patients after Stroke: A Cross-Sectional Study
Obesity is an important issue in global health care. Between 1975 and 2016, the proportion of obese individuals in the world nearly tripled. In fact, 39% of adults aged 18 years and older were overweight in 2016 and 13% were obese, using the traditional definition of overweight and obesity, namely, a body mass index (BMI)> 25 kg/m2 and> 30 kg/m2, respectively.1 Obesity is associated with a significant increase in mortality2,3 and the risk of many disorders, including metabolic and cardiovascular disease,4 cancer,5 infection,6 and physical limitations,7 as well as increasing healthcare costs.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2021 Category: Neurology Authors: Yoji Kokura, Shinta Nishioka Source Type: research

Predictors of Extended Length of Stay Following Treatment of Unruptured Adult Cerebral Aneurysms: A Study of The National Inpatient Sample
In an unprecedented era of soaring healthcare costs, payers and providers alike have started to place increased importance on measuring the quality of surgical procedures as a surrogate for operative success. One metric used is the length of hospital stay (LOS) during index admission. For the treatment of unruptured cerebral aneurysms, the determinants of extended length of stay are relatively unknown. The aim of this study was to identify the patient- and hospital-level factors associated with extended LOS following treatment for unruptured cerebral aneurysms.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2020 Category: Neurology Authors: Andrew B. Koo, Aladine A. Elsamadicy, I-Hsin Lin, Wyatt B. David, Nanthiya Sujijantarat, Corrado Santarosa, Branden J. Cord, Akli Zetchi, Ryan Hebert, Farhad Bahrassa, Ajay Malhotra, Charles C. Matouk Source Type: research

Prediction Model of Early Return to Hospital after Discharge Following Acute Ischemic Stroke.
CONCLUSIONS: Although CART analysis did not improve the prediction of an early return to hospital after stroke compared with logistic regression models, decision rules generated by CART can easily be interpreted and applied in clinical practice. PMID: 31544716 [PubMed - as supplied by publisher]
Source: Current Neurovascular Research - September 10, 2019 Category: Neurology Authors: Lee JD, Lee TH, Huang YC, Lee M, Kuo YW, Huang YC, Hu YH Tags: Curr Neurovasc Res Source Type: research

Pre-injury Comorbidities Are Associated With Functional Impairment and Post-concussive Symptoms at 3- and 6-Months After Mild Traumatic Brain Injury: A TRACK-TBI Study
Conclusions: Pre-injury psychiatric and pre-injury headache/migraine symptoms are risk factors for worse functional and post-concussive outcomes at 3- and 6-months post-mTBI. mTBI patients presenting to acute care should be evaluated for psychiatric and headache/migraine history, with lower thresholds for providing TBI education/resources, surveillance, and follow-up/referrals. Clinical Trial Registration: www.ClinicalTrials.gov, identifier NCT01565551. Introduction Traumatic brain injury (TBI) remains a significant cause of morbidity and mortality worldwide. In 2013 ~2.8 million TBI cases were recorded an...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research

The iScore predicts total healthcare costs early after hospitalization for an acute ischemic stroke
ConclusionsThe ischemic Stroke risk score can be useful as a predictor of healthcare utilization and costs early after hospitalization for an acute ischemic stroke.
Source: International Journal of Stroke - October 27, 2015 Category: Neurology Authors: Emmanuel M. Ewara, Wanrudee Isaranuwatchai, Dawn M. Bravata, Linda S. Williams, Jiming Fang, Jeffrey S. Hoch, Gustavo Saposnik, Tags: Research Source Type: research

Association of Pseudobulbar Affect Symptoms with Quality of Life and Healthcare Costs in Veterans with Traumatic Brain Injury
Pseudobulbar affect (PBA) is an affect disinhibition syndrome characterized by uncontrollable, exaggerated, and often inappropriate outbursts of crying or laughing.(Schiffer and Pope, 2005) It has been associated with disruption or damage to neural systems that modulate voluntary and involuntary emotional expression(Wortzel et al., 2008, Parvizi et al., 2009, Lauterbach et al., 2013)PBA has been identified in patients with a multitude of neurological disorders, including traumatic brain injury (TBI), amyotrophic lateral sclerosis, multiple sclerosis, stroke, and Alzheimer's disease.(Moore et al., 1997, Schiffer and Pope, 2...
Source: Journal of Affective Disorders - October 15, 2015 Category: Neurology Authors: James L. Rudolph, Jennifer R. Fonda, Phillip R. Hunt, Regina E. McGlinchey, William P. Milberg, Matthew W. Reynolds, Charles Yonan Source Type: research

Clinical and In-hospital Process Variables Are Associated With Hospital Length-of-Stay in Acute Ischemic Stroke Patients (P6.246)
CONCLUSIONS: For mild ischemic stroke patients, time to physical therapy evaluation (an in-hospital care process) was associated with LOS and likelihood of return to ED, whereas clinical factors (including mRS, NIHSS score, infarct location) were not. This suggests coordination of inpatient care processes, in addition to assessing and treating co-morbidities, could impact hospital LOS and, perhaps, long-term outcome.Disclosure: Dr. Kim has nothing to disclose. Dr. Conley has nothing to disclose. Dr. Kalanithi has nothing to disclose. Dr. Tai has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Kim, S., Conley, J., Kalanithi, L., Tai, W. Tags: Cerebrovascular Disease and Interventional Neurology: Thrombolysis Complications Source Type: research

Cost-Effectiveness of Recombinant Tissue-Type Plasminogen Activator Within 3 Hours of Acute Ischemic Stroke: Current Evidence Clinical Sciences
Conclusions— Our analysis supports earlier economic evaluations that r-tPA is a cost-effective method to treat stroke. Appropriate use of r-tPA should be prioritized nationally.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Boudreau, D. M., Guzauskas, G. F., Chen, E., Lalla, D., Tayama, D., Fagan, S. C., Veenstra, D. L. Tags: Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Trimming the fat in acute ischemic stroke: an assessment of 24‐h CT scans in tPA patients
ConclusionsOur results demonstrate that routine 24‐h computed tomography scan in patients without 24‐h National Institute of Health Stroke Scale worsening (especially those with baseline National Institute of Health Stroke Scale ≤10) is less likely to yield information that results in a deviation from standard acute stroke care. No patient without worsening and baseline National Institute of Health Stroke Scale ≤10 had parenchymal hematoma on 24‐h computed tomography. Application of the National Institute of Health Stroke Scale to distinguish patients who should have 24‐h follow‐up imaging from those who will...
Source: International Journal of Stroke - June 3, 2014 Category: Neurology Authors: Alexander J. George, Amelia K. Boehme, Casey R. Dunn, T. Beasley, James E. Siegler, Karen C. Albright, Ramy El Khoury, Sheryl Martin‐Schild Tags: Research Source Type: research

An Updated Cost-Effectiveness Analysis (CEA) of r-tPA for Acute Ischemic Stroke (AIS) Treated Within 3 Hours of Symptom Onset (P4.243)
CONCLUSIONS: Economic analyses suggest that r-tPA is highly cost-effective in treatment of AIS across numerous efficacy, safety, and mortality estimates. Further research on differences in long-term mortality in disabled and non-disabled patients is needed.Study Supported by: Genentech Inc.Disclosure: Dr. Boudreau has received personal compensation for activities with Genentech, Inc. Dr. Guzauskas has received personal compensation for activities with Genentech, Inc. Dr. Guzauskas has received research support from Genentech, Inc. Dr. Tayama has received personal compensation for activities with Genentech Inc. Dr. Tayam ho...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Boudreau, D., Guzauskas, G., Tayama, D., Fagan, S., Veenstra, D. Tags: Cerebrovascular Disease and Interventional Neurology: Endovascular Neurology Source Type: research

Is the Use of r-tPA in Mild Stroke Patients Cost-Effective? (P3.104)
CONCLUSIONS: Economic analyses based on preliminary clinical data suggest that r-tPA could be cost saving or highly cost-effective in the treatment of mild patients. Controlled clinical trials will be valuable in definitively establishing the clinical and economic value of r-tPA in mild stroke.Study Supported by: Genentech Inc.Disclosure: Dr. Guzauskas has received personal compensation for activities with Genentech, Inc. Dr. Guzauskas has received research support from Genentech, Inc. Dr. Chen has received personal compensation for activities with Genentech, Inc. as an employee. Dr. Khatri's institution has received resea...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Guzauskas, G., Chen, E., Khatri, P., Sandercock, P., Tayama, D., Veenstra, D. Tags: Cerebrovascular Disease and Interventional Neurology: t-PA Source Type: research