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Specialty: Neurology
Condition: Subarachnoid Hemorrhage
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Total 1836 results found since Jan 2013.
Prediction of stress-related gastrointestinal bleeding in patients with aneurysmal subarachnoid hemorrhage using caudate Hounsfield unit value in ASPECT score
ConclusionAmong aSAH patients, lower right caudate HU values indicated a higher risk of developing SRGB. Our findings provide further evidence for the relationship between the gastrointestinal system and the brain.
Source: Frontiers in Neurology - September 13, 2023 Category: Neurology Source Type: research
Case report: Fatal ischemic stroke induced by unruptured traumatic intracranial vertebral artery dissection
Intracranial vertebral artery dissection (IVAD) is rare and potentially fatal due to the risk of secondary subarachnoid hemorrhage once ruptured. Unruptured traumatic IVAD is even rarer and can result in ischemic stroke, yet mostly benign when timely diagnosed. Herein, we present an uncommon case of a patient who underwent a fatal ischemic stroke induced by unruptured traumatic IVAD. The patient was symptomatic soon after being physically assaulted but left untreated until acute deterioration for multiple brain infarctions occurred, secondary to IVAD-induced cerebellar stroke. Fifteen days later, he died, regardless of an ...
Source: Frontiers in Neurology - September 12, 2023 Category: Neurology Source Type: research
Amantadine for NeuroenhaNcement in acutE patients Study - a protocol for a prospective pilot proof of concept phase IIb study in intensive and intermediate care unit patients (ANNES)
Persisting coma is a common complication in (neuro)intensive care in neurological disease such as acute ischemic stroke, intracerebral hemorrhage or subarachnoid hemorrhage. Amantadine acts as a nicotinic rece...
Source: BMC Neurology - August 22, 2023 Category: Neurology Authors: Anna Hofmann, Corinna Blum, Constanze Single, Kamal Adeyemi, Patricia Schwarz, Vasileios Siokas, Tim W. Rattay, Helene A. H äberle, Reimer Riessen, Bettina Brendel, Iris Haug, Ruth Bösel, Manola Zago, Peter Martus, Ulf Ziemann, Annerose Mengel & hellip; Tags: Study Protocol Source Type: research
Response to: Aspirin and Subarachnoid Haemorrhage in the UK Biobank
Source: Translational Stroke Research - August 7, 2023 Category: Neurology Source Type: research
Assessment of rehabilitation following subarachnoid haemorrhage in China: findings from the Chinese Stroke Center Alliance
Rehabilitation improves functional recovery in subarachnoid hemorrhage (SAH) patients, and assessing patients for rehabilitation is the first step in this process. However, little is known about clinical pract...
Source: BMC Neurology - August 5, 2023 Category: Neurology Authors: Yi-Tong Chen, Mei-Ru Wu, Zi-Xiao Li, Hong-Qiu Gu, Qi Zhou, Dan-Dan Wang, Yong-Jun Wang and Xing-Quan Zhao Tags: Research Source Type: research
Thematic Analysis of Psychosocial Stressors and Adaptive Coping Strategies Among Informal Caregivers of Patients Surviving ICU Admission for Coma
ConclusionsIn response to substantial stressors, family caregivers of patients with SABI attempted to enact various psychological and behavioral coping strategies. They described avoidance and distraction as less helpful than other coping strategies but had difficulty engaging in alternative strategies because of their emotional distress. These findings can directly inform the development of additional resources to mitigate the long-term impact of acute psychological distress among this caregiver population.
Source: Neurocritical Care - July 31, 2023 Category: Neurology Source Type: research
Neurobehavioral Impairments Predict Specific Cerebral Damage in Rat Model of Subarachnoid Hemorrhage
This study suggests that recurring behavioral testing can accurately predict damage in specific brain regions, which could be developed into a clinical battery for early detection of SAH damage in humans, potentially improving early treatment and outcomes.
Source: Translational Stroke Research - July 26, 2023 Category: Neurology Source Type: research
CXCR2 antagonism attenuates neuroinflammation after subarachnoid hemorrhage
Subarachnoid hemorrhage (SAH) is the deadliest form of a severe cerebrovascular disease, with substantial morbidity and mortality.1 It has been increasingly recognized that SAH induces a series of pathophysiological processes, including neuronal apoptosis,2 neuroinflammatory reactions,3 blood ‒brain barrier disruption,4 and oxidative stress5 are key factors that affect the prognosis of SAH patients. Accumulating evidence has suggested that SAH seriously destroys the extracellular environment of glial cells and immune cells, and then those cells are activated, which produce and release excessive inflammatory cytokines, th...
Source: Journal of Stroke and Cerebrovascular Diseases - July 21, 2023 Category: Neurology Authors: Xiaolin Luo Source Type: research
Clopidogrel Is Associated with Reduced Likelihood of Aneurysmal Subarachnoid Hemorrhage: a Multi-Center Matched Retrospective Analysis
We present, to the best of our knowledge, the first large-scale multi-institutional analysis suggesting clopidogrel use is protective against intracranial aneurysm rupture. It is our hope that these data will guide future investigation, revealing the pathophysiologic underpinning of this association.
Source: Translational Stroke Research - July 20, 2023 Category: Neurology Source Type: research
Association between baseline pulse pressure and hospital mortality in non-traumatic subarachnoid hemorrhage patients: a retrospective cohort study
ConclusionFor patients with non-traumatic SAH, the association between baseline PP and risk of hospital mortality was non-linear, with an inflection point at 60 mmHg and a minimal risk at 57 to 68 mmHg (Q2) of baseline PP level.
Source: Frontiers in Neurology - July 17, 2023 Category: Neurology Source Type: research
Lifelong cerebrovascular disease burden among CADASIL patients: analysis from a global health research network
DiscussionEarly screening and targeted treatment strategies are warranted to help CADASIL patients with symptom management and risk mitigation.
Source: Frontiers in Neurology - July 14, 2023 Category: Neurology Source Type: research
Dynamic Measurements of Cerebral Blood Flow Responses to Cortical Spreading Depolarization in the Murine Endovascular Perforation Subarachnoid Hemorrhage Model
AbstractDelayed cerebral ischemia (DCI) is the most severe complication after subarachnoid hemorrhage (SAH), and cortical spreading depolarization (CSD) is believed to play a vital role in it. However, the dynamic changes in cerebral blood flow (CBF) in response to CSD in typical SAH models have not been well investigated. Here, SAH was established in mice with endovascular perforation. Subsequently, the spontaneous CBF dropped instantly and then returned to baseline rapidly. After KCl application to the cortex, subsequent hypoperfusion waves occurred across the groups, while a lower average perfusion level was found in th...
Source: Translational Stroke Research - June 29, 2023 Category: Neurology Source Type: research
Aspirin and Subarachnoid Haemorrhage in the UK Biobank
In this study, we aimed to clarify the association between aspirin and SAH in the general population. The UK Biobank is a prospective population-based cohort study. Sex, age, smoking, alcohol, medication use, hypertension, blood pressure, ischaemic heart disease and stroke were recorded at baseline assessments. Follow-up is conducted through linkages to National Health Service data including electronic, coded death certificate, hospital and primary care data. Cox proportional hazards modelling was used to analyse the association between aspirin use and SAH. Of the 501,060 participants included in the analysis, a total of 5...
Source: Translational Stroke Research - June 29, 2023 Category: Neurology Source Type: research
The clinical utility of dual-energy CT in post-thrombectomy care: Part 1, predictors and outcomes of subarachnoid and intraparenchymal hemorrhage
Dual-energy CT allows differentiation between blood and iodinated contrast. We aimed to determine predictors of subarachnoid and intraparenchymal hemorrhage on dual-energy CT performed immediately post-thrombectomy and the impact of these hemorrhages on 90-day outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - June 29, 2023 Category: Neurology Authors: Seoiyoung Ahn, Nishit Mummareddy, Steven G. Roth, Jacob Jo, Akshay Bhamidipati, Yeji Ko, Julie DiNitto, Rohan V. Chitale, Matthew R. Fusco, Michael T. Froehler Source Type: research
Hospital Discharge and Readmissions Before and During the COVID-19 Pandemic for California Acute Stroke Inpatients
Stroke is a leading cause of death and disability in the United States, with approximately 795,000 new strokes occurring annually, including acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH).1 The Coronavirus Disease 2019 (COVID-19) pandemic has impacted all levels of care for stroke patients, such as delays in initial presentation, reduction in acute therapies, limitations of in-patient resources, delays or lack of initiation of secondary stroke prevention therapy, and limitations in rehabilitation services after hospital discharge.
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2023 Category: Neurology Authors: George P. Albert, Daryl C. McHugh, Debra E. Roberts, Adam G. Kelly, Remi Okwechime, Robert G. Holloway, Benjamin P. George Source Type: research
