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Specialty: Neurology
Condition: Depression
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Total 2773 results found since Jan 2013.
Emotional and qualitative outcomes among patients with left and right hemisphere stroke
The differences in mental health outcomes of right and left hemisphere strokes are well studied; however, there is a long-standing controversy surrounding whether depression is associated with lateralization of stroke or not. In this investigation, we examined the effect of lesion location on post-stroke depression controlling for lesion size and hemiparesis in a longitudinal sample assessed at acute, subacute, and chronic timepoints. As a secondary aim, we further examined the effect of lesion location on self-reported difficulties across a wide array of domains. A series of 134 patients with left hemisphere strokes and 7...
Source: Frontiers in Neurology - November 17, 2022 Category: Neurology Source Type: research
Eye movement desensitization and reprocessing for post-stroke post-traumatic stress disorder: Case report using the three-phase approach
Brain Inj. 2022 Nov 13:1-10. doi: 10.1080/02699052.2022.2140833. Online ahead of print.ABSTRACTMedically-induced post-traumatic stress disorder (PTSD) is substantially more prevalent than PTSD in the general population. In people with stroke, it can impact as many as 23% of patients, with negative effects on mental health as well as stroke-related disability. Medically-induced PTSD may have unique features compared to other forms of PTSD, and therefore there is a pressing need to evaluate existing treatments for PTSD in this context. The current study reports on the feasibility, safety, and efficacy of Eye Movement Desensi...
Source: Brain Injury - November 14, 2022 Category: Neurology Authors: Colette M Smart Source Type: research
One-year recurrence of stroke and death in Lebanese survivors of first-ever stroke: Time-to-Event analysis
ConclusionHigher rates of stroke recurrence and death were observed in the first year following a stroke in Lebanon. Various factors were identified as significant determinants. Thus, health care providers and officials in Lebanon can use these findings to implement effective preventive strategies to best address the management of these factors to reduce the stroke burden and improve the short and long-term prognosis of stroke survivors.
Source: Frontiers in Neurology - November 14, 2022 Category: Neurology Source Type: research
Efficacy and safety of Buyang Huanwu Decoction in the treatment of post-stroke depression: A systematic review and meta-analysis of 15 randomized controlled trials
ConclusionCompared with antidepressants, the Buyang Huanwu Decoction is more effective and safer in the treatment of post-stroke depression patients. However, more high-quality studies are needed to further support the above conclusion.
Source: Frontiers in Neurology - November 4, 2022 Category: Neurology Source Type: research
HMGB1 in nervous system diseases: A common biomarker and potential therapeutic target
High-mobility group box-1 (HMGB1) is a nuclear protein associated with early inflammatory changes upon extracellular secretion expressed in various cells, including neurons and microglia. With the progress of research, neuroinflammation is believed to be involved in the pathogenesis of neurological diseases such as Parkinson's, epilepsy, and autism. As a key promoter of neuroinflammation, HMGB1 is thought to be involved in the pathogenesis of Parkinson's disease, stroke, traumatic brain injury, epilepsy, autism, depression, multiple sclerosis, and amyotrophic lateral sclerosis. However, in the clinic, HMGB1 has not been de...
Source: Frontiers in Neurology - October 31, 2022 Category: Neurology Source Type: research
White Matter Hyperintensities and Poststroke Apathy: A Fully Automated MRI Segmentation Study
Conclusion: This is an exploratory study that supports the view of PSA as a distinct syndrome from PSD mediated mainly by diffuse white matter hyperintensities, which suggests that WM disruption is an important pathway to the development of apathy in stroke patients.Cerebrovasc Dis
Source: Cerebrovascular Diseases - October 24, 2022 Category: Neurology Source Type: research
Post-Traumatic Stress Disorder after Stroke: A Systematic Review
Conclusions: PTSD is common after stroke. Further research is needed to clarify its time course and identify the neurochemical factors and brain circuits associated with the development of post-stroke PTSD. Randomized controlled treatment trials targeting PTSD in stroke are warranted.
Source: Neurology India - October 21, 2022 Category: Neurology Authors: Wai Kwong Tang Lisha Wang Kelvin K F Tsoi Stela Rutovic Jong S Kim Source Type: research
Protective Effect of Ergothioneine Against Stroke in Rodent Models
AbstractErgothioneine (ET) is a naturally occurring antioxidant and cytoprotective agent that is synthesized by fungi and certain bacteria. Recent studies have shown a beneficial effect of ET on neurological functions, including cognition and animal models of depression. The aim of this study is to elucidate a possible effect of ET in rodent models of stroke. Post-ischemic intracerebroventricular (i.c.v.) infusion of ET significantly reduced brain infarct volume by as early as 1 day after infusion in rats, as shown by triphenyltetrazolium chloride (TTC) assay. There was a dose-dependent increase in protection, from 50 to...
Source: NeuroMolecular Medicine - October 19, 2022 Category: Neurology Source Type: research
Variation in stroke care at the hospital level: A cross-sectional multicenter study
ConclusionWe identified high adherence to guidelines for some indicators, but lower rates with large interhospital variability for other recommendations also based on robust evidence. Improvement strategies should be implemented to improve the latter.
Source: Frontiers in Neurology - October 13, 2022 Category: Neurology Source Type: research
Functional outcome prediction of ischemic stroke patients with atrial fibrillation accepting post-acute care training
ConclusionIn the current study, nearly half of the enrolled patients showed favorable functional recovery. The outcome assessments seem to correlate well with NIHSS and Barthel Index scores, rather than mRS. The anxiety/depression and usual activities domains of the EQ-5D results are associated with and have a great impact after the patients undertake the PAC rehabilitative strategy. Moreover, the variables obtained through carotid duplex and plaque index might also play a significant role in determining the patient's functional outcome.
Source: Frontiers in Neurology - September 23, 2022 Category: Neurology Source Type: research
Cranial electrotherapy stimulation alleviates depression-like behavior of post-stroke depression rats by upregulating GPX4-mediated BDNF expression
Conclusion: CES improves depression-like behavior of PSD rats through upregulation of GPX4-mediated BDNF expression in the hippocampus.PMID:36116735 | DOI:10.1016/j.bbr.2022.114117
Source: Brain Research - September 18, 2022 Category: Neurology Authors: Xiaoju Wang Peng Xia Jiulong Song Ting Yang Changjun Yu Kai Cheng Anliang Chen Xueping Li Source Type: research
