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Total 154 results found since Jan 2013.
Multicomponent material property characterization of atherosclerotic human carotid arteries through a Bayesian Optimization based inverse finite element approach
CONCLUSION: The developed iFEM approach combined with the inverted GP model successfully predicted component-wise material properties of intact atherosclerotic human carotids ex-vivo under physiological-like loading conditions.SIGNIFICANCE: We developed a novel iFEM framework for the nonlinear, component-wise material characterization of atherosclerotic arteries and utilized it to obtain human atherosclerotic carotid material properties. The developed iFEM framework has great potential to be advanced for patient-specific in-vivo application.PMID:34864574 | DOI:10.1016/j.jmbbm.2021.104996
Source: Journal of the Mechanical Behavior of Biomedical Materials - December 5, 2021 Category: Materials Science Authors: Su Guvenir Torun Hakki M Torun Hendrik H G Hansen Chris L de Korte Antonius F W van der Steen Frank J H Gijsen Ali C Akyildiz Source Type: research
Combined acquisition of diffusion and T2*-weighted measurements using simultaneous multi-contrast magnetic resonance imaging
DiscussionThe simultaneous acquisition of multiple contrasts reduces the overall examination time and there is an inherent registration between contrasts. By using the results of this study to control saturation effects in SMC, the method enables rapid acquisition of distortion-matched and well-registered diffusion-weighted and T2*-weighted imaging, which could support rapid diagnosis and treatment of acute stroke.
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - December 2, 2021 Category: Materials Science Source Type: research
ASAP pH-Responsive Multifunctional Theranostic Rapamycin-Loaded Nanoparticles for Imaging and Treatment of Acute Ischemic Stroke
ACS Applied Materials& InterfacesDOI: 10.1021/acsami.1c16530
Source: ACS Applied Materials and Interfaces - November 22, 2021 Category: Materials Science Authors: Yan Cheng, Airong Cheng, Yanlong Jia, Lin Yang, Yan Ning, Liang Xu, Yazhi Zhong, Zerui Zhuang, Jitian Guan, Xiaolei Zhang, Yan Lin, Teng Zhou, Xiusong Fan, Jianwu Li, Peng Liu ⋈, Gen Yan⧓, and Renhua Wu Source Type: research
Human bone marrow-derived mesenchymal stem cells play a role as a vascular pericyte in the reconstruction of human BBB on the angiogenesis microfluidic chip
In this study, we established human BBB-like microvasculature on an angiogenesis microfluidic chip and analyzed the role of human pericytes (hPCs) and human astrocytes (hACs) on the architecture of human brain microvascular endothelial cells (hBMEC)-derived microvasculature on a chip. We found that human bone marrow mesenchymal stem cells (hBM-MSCs) play a role as perivascular pericytes in tight BBB reformation with a better vessel-constrictive capacity than that of hPCs, providing evidence of reparative stem cells on BBB repair rather than a paracrine effect. We also demonstrated that pericytes play an important role in v...
Source: Biomaterials - October 28, 2021 Category: Materials Science Authors: Sumin Kim Somin Lee Jungeun Lim Hyeri Choi Habin Kang Noo Li Jeon Youngsook Son Source Type: research
ASAP A Co-Doped Fe < sub > 3 < /sub > O < sub > 4 < /sub > Nanozyme Shows Enhanced Reactive Oxygen and Nitrogen Species Scavenging Activity and Ameliorates the Deleterious Effects of Ischemic Stroke
ACS Applied Materials& InterfacesDOI: 10.1021/acsami.1c06449
Source: ACS Applied Materials and Interfaces - September 21, 2021 Category: Materials Science Authors: Yunsheng Liu, Xiaojun Wang, Xiangzhu Li, Shanshan Qiao, Guodong Huang, Dirk Matthias Hermann, Thorsten Roland Doeppner, Muling Zeng, Wei Liu, Gelin Xu, Lijie Ren, Yuan Zhang, Wenlan Liu, Eudald Casals, Weiping Li, and Ya-Chao Wang Source Type: research
ASAP Embolic Stroke Model with Magnetic Nanoparticles
ACS Applied Materials& InterfacesDOI: 10.1021/acsami.1c11377
Source: ACS Applied Materials and Interfaces - September 8, 2021 Category: Materials Science Authors: Haoyuan Li, Zhipeng Yang, Qisheng Tang, Zhifeng Shi, and Ying Mao Source Type: research
ASAP Xenon Nanobubbles for the Image-Guided Preemptive Treatment of Acute Ischemic Stroke via Neuroprotection and Microcirculatory Restoration
ACS Applied Materials& InterfacesDOI: 10.1021/acsami.1c06014
Source: ACS Applied Materials and Interfaces - September 8, 2021 Category: Materials Science Authors: Juan Jin, Mei Li, Jing Li, Bin Li, Lei Duan, Fang Yang, and Ning Gu Source Type: research
Nanoparticles-mediated emerging approaches for effective treatment of ischemic stroke
Biomaterials. 2021 Aug 31;277:121111. doi: 10.1016/j.biomaterials.2021.121111. Online ahead of print.ABSTRACTIschemic stroke leads to high disability and mortality. The limited delivery efficiency of most therapeutic substances is a major challenge for effective treatment of ischemic stroke. Inspired by the prominent merit of nanoscale particles in brain targeting and blood-brain barrier (BBB) penetration, various functional nanoparticles have been designed as promising drug delivery platforms that are expected to improve the therapeutic effect of ischemic stroke. Based on the complex pathological mechanisms of ischemic st...
Source: Biomaterials - September 6, 2021 Category: Materials Science Authors: Wenxiu He Zhiwen Zhang Xianyi Sha Source Type: research
Fucoidan-functionalized polysaccharide submicroparticles loaded with alteplase for efficient targeted thrombolytic therapy
Biomaterials. 2021 Aug 30;277:121102. doi: 10.1016/j.biomaterials.2021.121102. Online ahead of print.ABSTRACTIntravenous administration of fibrinolytic drugs is the standard treatment of acute thrombotic diseases. However, current fibrinolytics exhibit limited clinical efficacy because of their short plasma half-lives and might trigger hemorrhagic transformations. Therefore, it is mandatory to develop innovative nanomedicine-based solutions for more efficient and safer thrombolysis with biocompatible and biodegradable thrombus-targeted nanocarrier. Herein, fucoidan-functionalized hydrogel polysaccharide submicroparticles w...
Source: Biomaterials - September 5, 2021 Category: Materials Science Authors: Alina Zenych Charl ène Jacqmarcq Rachida Aid Louise Fournier Laura M Forero Ramirez Fr édéric Chaubet Thomas Bonnard Denis Vivien Didier Letourneur C édric Chauvierre Source Type: research
CAFT: a deep learning-based comprehensive abdominal fat analysis tool for large cohort studies
ConclusionsDL-based, comprehensive SSAT, DSAT, and VAT analysis tool showed high accuracy and reproducibility and provided a comprehensive fat compartment composition analysis and visualization in less than 10 s.
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - August 2, 2021 Category: Materials Science Source Type: research
Combined measurement and simulation of piston ring cylinder liner contacts with a reciprocating long-stroke tribometer
Publication date: Available online 23 June 2021Source: Tribology InternationalAuthor(s): Björn Michelberger, Dirk Jaitner, Andreas Hagel, Patrick Striemann, Benjamin Kröger, Andreas Leson, Andrés Fabián Lasagni
Source: Tribology International - June 25, 2021 Category: Materials Science Source Type: research
Experimental investigation on 4-Stroke DI diesel engine using methyl esters of Polanga oil and Thyme oil at varying injection pressures
Publication date: Available online 17 May 2021Source: Materials Today: ProceedingsAuthor(s): J. Senthil kumar, B.R. Ramesh Bapu, S. Ganesan, S. Mahalingam, Hamilton V. De Paul, G. Venkadesh Prasad
Source: Materials Today: Proceedings - May 18, 2021 Category: Materials Science Source Type: research
Design and thermal analysis of six stroke engine
Publication date: Available online 3 May 2021Source: Materials Today: ProceedingsAuthor(s): D.N. Thatoi, Sanjeev Gaur
Source: Materials Today: Proceedings - May 5, 2021 Category: Materials Science Source Type: research
