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Fracture treatment in atrophic mandible
CONCLUSIONS: Treatment of fractures in atrophic mandibles with plates and screws is a reliable procedure. Luhr classification provide useful guidance regarding the use of bone grafts for best osteogenic response in the fracture. This treatment allows a quick restart of the feeding by mouth and movilization of the patients.PMID:37084311 | DOI:10.24875/CIRU.21000281
Source: Cirugia y Cirujanos - April 21, 2023 Category: Surgery Authors: Ricardo Cienfuegos Source Type: research

Cardiac transplant and exercise cardiac rehabilitation
AbstractCardiac transplantation is the final therapeutic option for patients with end-stage heart failure. Most patients experience a favorable functional ability post-transplant. However, episodes of acute rejection, and multiple comorbidities such as hypertension, diabetes mellitus, chronic kidney disease and cardiac allograft vasculopathy are common. The number of transplants has increased steadily over the past two decades with 3,817 operations performed in the United States in 2021. Patients have abnormal exercise physiologic responses related to surgical cardiac denervation, diastolic dysfunction, and the legacy of r...
Source: Heart Failure Reviews - April 4, 2023 Category: Cardiology Source Type: research

Platelets at the Vessel Wall in Non-Thrombotic Disease
Circ Res. 2023 Mar 17;132(6):775-790. doi: 10.1161/CIRCRESAHA.122.321566. Epub 2023 Mar 16.ABSTRACTPlatelets are small, anucleate entities that bud from megakaryocytes in the bone marrow. Among circulating cells, platelets are the most abundant cell, traditionally involved in regulating the balance between thrombosis (the terminal event of platelet activation) and hemostasis (a protective response to tissue injury). Although platelets lack the precise cellular control offered by nucleate cells, they are in fact very dynamic cells, enriched in preformed RNA that allows them the capability of de novo protein synthesis which ...
Source: Circulation Research - March 17, 2023 Category: Cardiology Authors: Anu Aggarwal Courtney L Jennings Emily Manning Scott J Cameron Source Type: research

Impact of occurrence of cardiac arrest in the donor on long ‐term outcomes of pediatric heart transplantation
ConclusionThe occurrence of donor cardiac arrest has no impact on long-term survival in pediatric heart transplant recipients.
Source: Journal of Cardiac Surgery - November 8, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Sandeep Sainathan, Sameh Said, Tamy Tsujimoto, Feng ‐Chang Lin, Leonardo Mullinari, Mahesh Sharma Tags: ORIGINAL ARTICLE Source Type: research

FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation
Autophagy. 2022 Sep 28:1-20. doi: 10.1080/15548627.2022.2116833. Online ahead of print.ABSTRACTProper termination of cell-death-induced neural inflammation is the premise of tissue repair in acute ischemic stroke (AIS). Macrophages scavenge cell corpses/debris and produce inflammatory mediators that orchestrate immune responses. Here, we report that FOXP3, the key immune-repressive transcription factor of Tregs, is conditionally expressed in macrophages in stroke lesion. FOXP3 ablation in macrophages results in detrimental stroke outcomes, emphasizing the beneficial role of FOXP3+ macrophages. FOXP3+ macrophages are distin...
Source: Autophagy - September 28, 2022 Category: Cytology Authors: Wei Cai Mengyan Hu Chunyi Li Ruizhen Wu Danli Lu Chichu Xie Wei Zhang Tiemei Li Shishi Shen Huipeng Huang Wei Qiu Quentin Liu Yan Lu Zhengqi Lu Source Type: research

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