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Total 271 results found since Jan 2013.

PET scans may improve brain injury diagnosis
ConclusionThis is a valuable diagnostic study that tested how accurate PET and fMRI imaging are at distinguishing between different levels of conscious state and helping to predict recovery. Diagnostic assessments are traditionally made using bedside clinical tests – but as the researchers say, judging the level of awareness in people with severe brain damage can be difficult.In particular, the researchers wanted to see whether the scans could accurately distinguish between people with “unresponsive wakefulness syndrome” and “minimally conscious state”, as distinguishing between these two states can have impor...
Source: NHS News Feed - April 16, 2014 Category: Consumer Health News Tags: Medical practice Neurology Source Type: news

Intensive virtual reality-based training for upper limb motor function in chronic stroke: a feasibility study using a single case experimental design and fMRI.
Conclusion: The VR-based intervention was feasible, safe, and intense. Adjustable application settings maintained training challenge and patient motivation. ADL-relevant UL functional improvements persisted at FU and were related to changed cortical activation patterns. Implications for Rehabilitation YouGrabber trains uni- and bimanual upper motor function. Its application is feasible, safe, and intense. The control of the virtual arms can be done in three main ways: (a) normal (b) virtual mirror therapy, or (c) virtual following. The mirroring feature provides an illusion of affected limb movements during the period when...
Source: Disability and Rehabilitation. Assistive Technology. - April 14, 2014 Category: Rehabilitation Authors: Schuster-Amft C, Henneke A, Hartog-Keisker B, Holper L, Siekierka E, Chevrier E, Pyk P, Kollias S, Kiper D, Eng K Tags: Disabil Rehabil Assist Technol Source Type: research

Comparing Semi-quantitative and Volumetric Measurements of MRI White Matter Hyperintensities: The Northern Manhattan Study (S62.007)
CONCLUSIONS: Our volumetric and visual rating measures of WMH were strongly correlated, but the volumetric measure was associated with more risk factors in this community-based sample. User-friendly WMH scales that capture vascular risk are needed to develop risk-prediction scores for WMH lesion burden.Study Supported by:Evelyn F. McKnight Brain Institute and NINDS (R37 NS 29993; K02 NS 059729)Disclosure: Dr. Oboudiyat has nothing to disclose. Dr. Gardener has nothing to disclose. Dr. Marquez has nothing to disclose. Dr. Sacco has nothing to disclose. Dr. DeCarli has received personal compensation in an editorial capacity ...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Oboudiyat, C., Gardener, H., Marquez, C., Elkind, M., Sacco, R., DeCarli, C., Wright, C. Tags: Cerebrovascular Disease and Interventional Neurology: Cognitive and Behavioral Source Type: research

Phenotypic Differences In The Distribution Of Gray Matter Lesions In Multiple Sclerosis And Their Relevance To Cognition (P5.013)
CONCLUSIONS:There is a fronto-temporal dominance and occipital paucity, of cortical lesions. Cognitive deficits commonly ascribed to frontal and temporal lobe functions are associated with cortical or juxtacortical lesion load in the corresponding lobe independent of any effect of white matter lesion load.Study Supported by:MS Society of Great Britain and Northern Ireland, and the UCLH Comprehensive Biomedical Research Centre.Disclosure: Dr. Sethi has received personal compensation for activities with Biogen Idec and Novartis. Dr. Sethi has received research support from the Multiple Sclerosis Society of Great Britain and ...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Sethi, V., Yousry, T., Muhlert, N., Tozer, D., Altmann, D., Ron, M., Wheeler-Kingshott, C., Miller, D., Chard, D. Tags: MS and CNS Inflammatory Disease II Source Type: research

Stroke Risk Factors, Subtypes, and 30-Day Case Fatality in Abuja, Nigeria (P1.121)
CONCLUSIONS: Although hypertension, obesity, diabetes mellitus, and atrial fibrillation were important stroke risk factors, in many patients, these were detected only after a stroke. While the commonest stroke subtype was cerebral infarction, observed in almost two-third of patients, SAH was associated with the highest case-fatality rate at 30 days of 44.4%. Larger population-based studies are planned.Study Supported by: nilDisclosure: Dr. Bwala has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Bwala, S. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Subtype Source Type: research

Treating Neglect by Body Movements: A Case Report and Follow-Up Study (P3.043)
DISCUSSION: Our initial neglect patient named left-sided objects better when cued to move midline structures to the left. If midline structures are represented more bilaterally in the brain, they may be less affected by body-centered "aiming" bias. Future research would examine whether cueing with the nose/tongue is selectively helpful for patients with more severe neglect or with "aiming" bias and limb akinesia.STUDY SUPPORTED BY: National Institutes of Health and Kessler Foundation.Disclosure: Dr. Chaudhari has nothing to disclose. Dr. Pigott has nothing to disclose. Dr. Chen has nothing to disclose. Dr. Barrett has rece...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Chaudhari, A., Pigott, K., Chen, P., Barrett, A. Tags: Neural Repair and Neuro-rehabilitation: Clinical Source Type: research

Changing clinical patterns and increasing prevalence in CADASIL
ConclusionsCADASIL prevalence is at least 4.6 per 100,000 adults. Median age of first stroke may be older than previously thought. Clinicians should consider CADASIL in the differential diagnosis even in older patients with stroke.
Source: Acta Neurologica Scandinavica - April 1, 2014 Category: Neurology Authors: F. C. Moreton, S. S. M. Razvi, R. Davidson, K. W. Muir Tags: Original Article Source Type: research

Eating Fruits and Veggies Equals Healthy Arteries in Later Years
Previous studies have found that middle-aged adults whose diet consists of a high proportion of fruits and vegetables are less likely to have a heart attack or stroke, but the relationship between fruit and vegetable consumption during young adulthood and heart disease later in life was less clear. To study this concept, researchers evaluated the association between dietary intake of fruits and vegetables in young adults and the presence of coronary artery calcification (CAC) 20 years later. CAC scores, which were obtained using a CT scan, provide a direct estimate of the amount of plaque in the coronary arteries.
Source: Disabled World - March 29, 2014 Category: Disability Tags: Fruits and Vegetables Source Type: news

Eating Fruits and Vegies Equals Healthy Arteries in Later Years
Previous studies have found that middle-aged adults whose diet consists of a high proportion of fruits and vegetables are less likely to have a heart attack or stroke, but the relationship between fruit and vegetable consumption during young adulthood and heart disease later in life was less clear. To study this concept, researchers evaluated the association between dietary intake of fruits and vegetables in young adults and the presence of coronary artery calcification (CAC) 20 years later. CAC scores, which were obtained using a CT scan, provide a direct estimate of the amount of plaque in the coronary arteries.
Source: Disabled World - March 28, 2014 Category: Disability Tags: Fruits and Vegetables Source Type: news

Do No Harm: Stories of Life, Death and Brain Surgery review
Patients see neurosurgeons as gods, but what is the reality? Henry Marsh has written a memoir of startling candourWe go to doctors for help and healing; we don't expect them to make us worse. Most people know the aphorism taught to medical students, attributed to the ancient Greek Hippocrates but timeless in its quiet sanity: "First, do no harm." But many medical treatments do cause harm: learning how to navigate the risks of drug therapies, as well as the catastrophic consequences of botched or inadvised surgical operations, is a big part of why training doctors takes so long. Even the simplest of therapies carries the ri...
Source: Guardian Unlimited Science - March 19, 2014 Category: Science Authors: Gavin Francis Tags: The Guardian Private healthcare Culture Society Reviews Books Neuroscience UK news Hospitals NHS Source Type: news

Routine serum C‐reactive protein and stroke outcome after intravenous thrombolysis
ConclusionsAccording to our findings, elevated routine serum CRP measured within 24 h after admission does not seem to independently affect the outcome in patients receiving intravenous thrombolysis for stroke. However, further studies of blood samples taken directly before the treatment are needed.
Source: Acta Neurologica Scandinavica - February 20, 2014 Category: Neurology Authors: M. Karlinski, J. Bembenek, K. Grabska, A. Kobayashi, A. Baranowska, T. Litwin, A. Czlonkowska Tags: Original Article Source Type: research

Quick magnesium treatment fails to improve stroke outcomes, but study has silver lining
In the first study of its kind, a consortium led by UCLA physicians found that giving stroke patients intravenous magnesium within an hour of the onset of symptoms does not improve stroke outcomes.   However, the 8-year trial did find that with the help of paramedics in the field, intravenous medications can frequently be administered to stroke victims within that so-called "golden hour," during which they have the best chance to survive and avoid debilitating, long-term neurological damage.   The latter finding is a "game-changer," said Dr. Jeffrey Saver, director of the UCLA Stroke Center and a professor of ...
Source: UCLA Newsroom: Health Sciences - February 13, 2014 Category: Universities & Medical Training Source Type: news

Association between neurological disorders, functioning, and mortality in the elderly
ConclusionsWe found that not only specific neurological disorders, but also earlier symptoms are related to impaired functioning and predict mortality in the elderly. These findings have potential clinical relevance for screening and early detection of individuals at risk.
Source: Acta Neurologica Scandinavica - February 3, 2014 Category: Neurology Authors: M. E. Czira, B. T. Baune, A. Roesler, K. Pfadenhauer, C. Trenkwalder, K. Berger Tags: Original Article Source Type: research

Quality indicators in acute stroke care: a prospective observational survey in 13 Italian regions.
CONCLUSIONS: Our data confirm the need of quality monitoring in stroke care. Although SU patients showed a better adherence to quality indicators, overall compliance was unsatisfactory. PMID: 24293350 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - November 29, 2013 Category: Geriatrics Authors: Di Carlo A, Accetta G, Bellan M, Terni G, Lamassa M, Facchini R, Biggeri A, Inzitari D, Ferro S, For the National Stroke Care Group Tags: Aging Clin Exp Res Source Type: research