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Morphometrical features of left atrial appendage in the AF patients subjected to left atrial appendage closure
CONCLUSIONS: Important morphometrical differences in LAA orifice have been found, which was significantly larger and more oval in patients with atrial fibrillation compared to healthy controls. Although no difference in LAA body type and size was observed; the LAA ejection fraction was significantly lower in atrial fibrillation rhythm patients.PMID:36165901 | DOI:10.5603/FM.a2022.0080
Source: Folia Morphologica - September 27, 2022 Category: Anatomy Authors: K M Slodowska J Batko J P Holda D Dudkiewicz M Koziej R Litwinowicz K Bartus M K Holda Source Type: research

A Morphological Study of Left Atrial Appendage in Egyptian patients Using multidetector computed tomography (MDCT)
ConclusionEgyptian patients had predominantly windsock morphology in males and cactus morphology in females.
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

Relations between left atrial appendage contrast retention and thromboembolic risk in patients with atrial fibrillation
This study was designed to assess the relations between LAA contrast retention and thrombogenesis risk of the LAA in patients with non-valvular atrial fibrillation. A total of 132 consecutive patients who underwent LAAO were enrolled. The data collected from computed tomography (CT), transthoracic echocardiography (TTE), transesophageal echocardiography (TEE) and blood samples were analyzed. Univariate and multivariate logistic regression models were constructed to assess the association between CR, left atrial appendage thrombus (LAAT) and other factors. Contrast retention was observed in 33 patients, accounting for 25% o...
Source: Journal of Thrombosis and Thrombolysis - June 15, 2021 Category: Hematology Source Type: research

Left atrial appendage morphology and cardiac function in patients with sinus rhythm
ConclusionsThese findings suggest that impaired LA and LAA functions are related to changes of the LAA in patients with sinus rhythm.
Source: Journal of Echocardiography - January 15, 2020 Category: Cardiology Source Type: research

The left atrial appendage morphology is associated with embolic stroke subtypes using a simple classification system: A proof of concept study
The current left atrial appendage (LAA) classification system (cLAA-CS) categorizes it into 4 morphologies: chicken wing (CW), windsock, cactus, and cauliflower, though there is limited data on either reliability or associations between different morphologies and stroke risk. We aimed to develop a simplified LAA classification system and to determine its relationship to embolic stroke subtypes.
Source: Journal of Cardiovascular Computed Tomography - April 15, 2019 Category: Radiology Authors: Shadi Yaghi, Andrew Chang, Ronald Akiki, Scott Collins, Tracy Novack, Morgan Hemendinger, Ashley Schomer, Brain Mac Grory, Shawna Cutting, Tina Burton, Christopher Song, Athena Poppas, Ryan McTaggart, Mahesh Jayaraman, Alexander Merkler, Hooman Kamel, Mit Tags: Research paper Source Type: research

Correlation between left atrial appendage morphology and flow velocity in patients with paroxysmal atrial fibrillation
Conclusion LAA morphology is a significant determinant of LAAFV, suggesting an underlying mechanism for the association between LAA morphology and embolic events.
Source: European Journal of Echocardiography - December 18, 2015 Category: Cardiology Authors: Fukushima, K., Fukushima, N., Kato, K., Ejima, K., Sato, H., Fukushima, K., Saito, C., Hayashi, K., Arai, K., Manaka, T., Ashihara, K., Shoda, M., Hagiwara, N. Tags: ORIGINAL ARTICLES Source Type: research

Safety and effectiveness of compassionate use of LARIAT® device for epicardial ligation of anatomically complex left atrial appendages
Conclusions Despite a high preclusion rate, percutaneous LAA ligation may be safely and effectively performed on compassionate grounds using the first-generation LARIAT® device with surgical standby in patients with large and complex LAA.
Source: Journal of Interventional Cardiac Electrophysiology - January 17, 2015 Category: Cardiology Source Type: research

Left atrial appendage morphology in patients with atrial fibrillation in China: implications for stroke risk assessment from a single center study.
CONCLUSION: LAA analysis can potentially be used to inform guidance on the implication for stroke risk assessment. PMID: 25533823 [PubMed - in process]
Source: Chinese Medical Journal - December 1, 2014 Category: Journals (General) Authors: Kong B, Liu Y, Hu H, Wang L, Fan Y, Mei Y, Liu W, Liao J, Liu D, Xing D, Huang H Tags: Chin Med J (Engl) Source Type: research

Relationship between left atrial appendage morphology and stroke in patients with atrial fibrillation
Background: Atrial fibrillation (AF) is an important cause of stroke. Given the morbidity and mortality associated with stroke, the risk stratification of patients based on left atrial appendage (LAA) characteristics is of great interest.Objective: To explore the association between LAA morphology and LAA characteristics including the extent of trabeculations, orifice diameter, and length with prevalent stroke in a large cohort of patients with drug refractory AF who underwent AF ablation to develop mechanistic insight regarding the risk of stroke.Methods: An institutional cohort of 1063 patients referred for AF ablation f...
Source: Heart Rhythm - September 27, 2013 Category: Cardiology Authors: Irfan M. Khurram, Jane Dewire, Michael Mager, Farhan Maqbool, Stefan L. Zimmerman, Vadim Zipunnikov, Roy Beinart, Joseph E. Marine, David D. Spragg, Ronald D. Berger, Hiroshi Ashikaga, Saman Nazarian, Hugh Calkins Tags: Atrial Fibrillation Source Type: research

Anatomical characteristics of the left atrial appendage in cardiogenic stroke with low CHADS2 scores
Conclusions: The LAA anatomy might be useful for predicting strokes in patients with nonvalvular AF who have low CHADS2 scores.
Source: Heart Rhythm - February 4, 2013 Category: Cardiology Authors: Takehiro Kimura, Seiji Takatsuki, Kohei Inagawa, Yoshinori Katsumata, Takahiko Nishiyama, Nobuhiro Nishiyama, Kotaro Fukumoto, Yoshiyasu Aizawa, Yoko Tanimoto, Kojiro Tanimoto, Masahiro Jinzaki, Keiichi Fukuda Tags: Creative Concepts Source Type: research