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Percutaneous Endocardial Occlusion of Incompletely Surgically Ligated Left Atrial Appendage
ConclusionPercutaneous endocardial occlusion of ISLL is feasible using an Amplatzer Septal Occluder device. Additional studies are required to evaluate the long‐term safety and efficacy of this therapeutic treatment strategy in patients with ISLL.
Source: Journal of Cardiovascular Electrophysiology - June 10, 2013 Category: Cardiology Authors: ARASH ARYANA, DIOGO CAVACO, ARVIN ARTHUR, PADRAIG GEAROID O'NEILL, PEDRO ADRAGÃO, ANDRÉ D'AVILA Tags: Original Article Source Type: research

Urgent surgery compared with fibrinolytic therapy for the treatment of left-sided prosthetic heart valve thrombosis: a systematic review and meta-analysis of observational studies
Conclusion Urgent surgery was not superior to FT at restoring valve function, but substantially reduced the occurrence of thrombo-embolic events, major bleeding, and recurrent PVT. In experienced centres, urgent surgery should probably be preferred over FT for treating left-sided PVT, pending the results of randomized controlled trials.
Source: European Heart Journal - June 1, 2013 Category: Cardiology Authors: Karthikeyan, G., Senguttuvan, N. B., Joseph, J., Devasenapathy, N., Bahl, V. K., Airan, B. Tags: Valvular heart disease Source Type: research

Percutaneous Endocardial Occlusion of Incompletely Surgically‐Ligated Left Atrial Appendage
ConclusionPercutaneous endocardial occlusion of ISLL is feasible using an Amplatzer Septal Occluder device. Additional studies are required to evaluate the long term safety and efficacy of this therapeutic treatment strategy in patients with ISLL.This article is protected by copyright. All rights reserved.
Source: Journal of Cardiovascular Electrophysiology - May 1, 2013 Category: Cardiology Authors: ARASH ARYANA, DIOGO CAVACO, ARVIN ARTHUR, PADRAIG GEAROID O'NEILL, PEDRO ADRAGÃO, ANDRÉ D'AVILA Tags: Original Clinical Source Type: research

Anticoagulation management in patients with mechanical heart valves having pacemaker or defibrillator insertion
Conclusion: We found a low risk for stroke in the absence of postoperative bridging. For patients with device replacement surgery reversal of the anticoagulant effect at the time of procedure might reduce the risk for pocket hematoma, but this requires prospective evaluation including the risk of thromboembolism.
Source: Thrombosis Research - January 31, 2013 Category: Hematology Authors: S. Schulman, J. Schoenberg, S. Divakara Menon, A.C. Spyropoulos, J.S. Healey, J.W. Eikelboom Tags: Clinical Studies Source Type: research

Contribution of Three-Dimensional Transesophageal Echocardiography to Diagnosis and Management of Thrombosis of a St. Jude Mechanical Prosthesis in the Aortic Valve Position
Prosthetic valve thrombosis (PVT) is a serious complication after cardiac valve replacement and usually requires urgent management with either thrombolysis or surgery. A 38-year-old woman with history of ischemic stroke and multiple valvular surgeries including aortic St. Jude mechanical valve replacement (St. Jude Medical, St. Paul, Minnesota) presented with new-onset dyspnea on exertion. Transthoracic echocardiography and 2-dimensional transesophageal echocardiography (TEE) suggested an abnormally high gradient across the aortic valve () but could not determine the cause of the stenosis (, ). Three-dimensional (3D) TEE...
Source: The American Journal of Cardiology - January 4, 2013 Category: Cardiology Authors: Kan Liu Tags: Readers' Comments Source Type: research

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