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Abstract 221: National and Regional Trends in Hospitalizations for Ischemic Stroke after Acute Myocardial Infarction in the United States: 1999-2010 Poster Session II
Conclusions: From 1999 to 2010, the hospitalization rates of ischemic stroke after AMI decreased overall and for demographic subgroups and those undergoing PCI, CABG, or no revascularization. Declines were seen for all regions, but were consistently higher for stroke belt states. Post-AMI strokes 30-day mortality rates decreased over time.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Shi, R., Wang, Y., Lichtman, J. H., Krumholz, H. M., Dharmarajan, K., Masoudi, F. A., Dodson, J. A., Chen, J., Chaudhry, S. I., Spertus, J. A., Nallamothu, B. K. Tags: Poster Session II Source Type: research

Left Atrial Appendage Closure: Is the Strategy Enough to Lower Long-Term Stroke Risk?
AbstractPurpose of ReviewLeft atrial appendage closure (LAAC) emerged as a promising site-directed therapy to mitigate stroke risk in patients ineligible for long-term oral anticoagulation. We sought to summarize the current evidence regarding the role of LAAC on long-term risk of ischemic stroke and systemic thromboembolism.Recent FindingsData from EWOLUTION registry provides real world evidence on the 1-year outcomes of LAAC by WATCHMAN device. The annual ischemic stroke rate was 1.1 per 100 patient-years, as opposed to the CHADS2VASC score-predicted stroke rate of 7.2% (84% relative risk reduction). No differences in de...
Source: Current Cardiovascular Risk Reports - August 19, 2017 Category: Cardiology Source Type: research

Neurological Events Following Transcatheter Aortic Valve Replacement and Their Predictors: A Report From the CoreValve Trials Structural Heart Disease
Conclusions— Predictors of early stroke after TAVR included clinical and procedural factors; predictors of later stroke were limited to patient but not anatomic characteristics. These findings indicate that further refinement of imaging to identify anatomic factors predisposing to embolization may help improve stroke prediction in patients undergoing TAVR. Clinical Trial Registrations— URL: http://www.clinicaltrials.gov. Unique identifiers: NCT01240902, NCT01531374.
Source: Circulation: Cardiovascular Interventions - September 5, 2016 Category: Cardiology Authors: Kleiman, N. S., Maini, B. J., Reardon, M. J., Conte, J., Katz, S., Rajagopal, V., Kauten, J., Hartman, A., McKay, R., Hagberg, R., Huang, J., Popma, J., for the CoreValve Investigators Tags: Valvular Heart Disease, Cardiovascular Surgery, Catheter-Based Coronary and Valvular Interventions, Cerebrovascular Disease/Stroke Structural Heart Disease Source Type: research

Renal dysfunction and long-term risk of ischemic and hemorrhagic stroke following coronary artery bypass grafting
Conclusions: Renal dysfunction is associated with increased long-term risk of stroke after primary isolated CABG. The impact of renal dysfunction on risk of stroke appears to be similar for both men and women.
Source: International Journal of Cardiology - December 6, 2012 Category: Cardiology Authors: Martin J. Holzmann, Erik Ahlbäck, Anders Jeppsson, Ulrik Sartipy Tags: Original Articles Source Type: research

Long-Term Risk of Stroke in Patients With Type 1 and Type 2 Diabetes Following Coronary Artery Bypass Grafting Cardiovascular Surgery
Conclusions The long-term risk for stroke after coronary artery bypass grafting was increased in patients with type 1 and type 2 diabetes, compared to patients with no diabetes.
Source: JAHA:Journal of the American Heart Association - November 9, 2015 Category: Cardiology Authors: Nystrom, T., Holzmann, M. J., Sartipy, U. Tags: Cardiovascular Surgery Source Type: research

The increased risk of stroke/transient ischemic attack in women with a cardiac implantable electronic device is not associated with a higher atrial fibrillation burden
ConclusionsAmong patients implanted with a CIED, an AF burden of at least 5  min is a common finding, (44% of patients). Female patients have a risk of stroke and TIAs that is around two-fold that of male patients, but this increased risk cannot be ascribed to a higher burden of AF or to differences in the evolution to permanent AF.Clinical Trial RegistrationClinicalTrials.gov Identifier: NCT01007474
Source: Europace - December 22, 2016 Category: Cardiology Source Type: research

Impact of Left Atrial Appendage Closure During Cardiac Surgery on the Occurrence of Early Postoperative Atrial Fibrillation, Stroke, and Mortality: A Propensity Score Matched Analysis of 10,633 Patients.
CONCLUSIONS: -After adjustment for treatment allocation bias, LAA closure during routine cardiac surgery was significantly associated with an increased risk of early POAF, but did not influence the risk of stroke or mortality. It remains uncertain whether prophylactic exclusion of the LAA is warranted for stroke prevention during non-AF-related cardiac surgery. PMID: 27903589 [PubMed - as supplied by publisher]
Source: Circulation - November 29, 2016 Category: Cardiology Authors: Melduni RM, Schaff HV, Lee HC, Gersh BJ, Noseworthy PA, Bailey KR, Ammash NM, Cha SS, Fatema K, Wysokinski WE, Seward JB, Packer DL, Rihal CS, Asirvatham SJ Tags: Circulation Source Type: research

Aspirin Instead of Oral Anticoagulant Prescription in Atrial Fibrillation Patients at Risk for Stroke
ConclusionsIn a large, real-world cardiac outpatient population of AF patients with a moderate to high risk of stroke, more than 1 in 3 were treated with aspirin alone without OAC. Specific patient characteristics predicted prescription of aspirin therapy over OAC.
Source: Journal of the American College of Cardiology - June 21, 2016 Category: Cardiology Source Type: research

Epicardial left atrial appendage AtriClip occlusion reduces the incidence of stroke in patients with atrial fibrillation undergoing cardiac surgery
ConclusionThe long-term results from our first-in-man prospective human trial plus our institutional registry of epicardial LAA occlusion with the AtriClip in patients with AF undergoing cardiac surgery demonstrate the safety and durability of the procedure. In addition, our data are suggestive for the potential efficacy of LAA occlusion in reducing the incidence of stroke. If validated in future large randomized trials, routine LAA occlusion in patients undergoing cardiac surgery (with contraindications to treatment with oral anticoagulants) may represent a reasonable adjunct procedure to reduce the risk of future stroke....
Source: Europace - July 18, 2017 Category: Cardiology Source Type: research

Stroke Rates Following Surgical Versus Percutaneous Revascularization for Ischemic Heart Disease
AbstractPurpose of ReviewCoronary revascularization is a commonly performed major procedure in the hospitals. Stroke is one of the dreaded complications after coronary revascularization procedures. The focus of this review is to understand the stroke risk in percutaneous cutaneous intervention (PCI) and coronary artery bypass grafting (CABG) procedures.Recent FindingsAvailable data show that PCI offers less procedural stroke risk compared to CABG although the survival benefits of CABG are better in certain scenarios. Innovative advancements in techniques, pre-procedural optimum medical therapy (OMT), intraoperative neuro-m...
Source: Current Cardiology Reports - March 15, 2021 Category: Cardiology Source Type: research

Influencing Factors for Early Acute Cerebrovascular Accidents in Patients with Stroke History following Off-pump Coronary Artery Bypass Grafting
Conclusions: This study indicated that patients with severe bilateral carotid stenosis, the left ventricular ejection fraction ≤35%, the postoperative acute myocardial infarction, postoperative atrial fibrillation and postoperative hypotension were more likely to suffer from early acute cerebrovascular accidents when they received OPCAB. Application of Enclose® II proximal anastomotic device may decrease the incidence of early acute cerebrovascular accidents during OPCAB.
Source: Heart, Lung and Circulation - February 10, 2014 Category: Cardiology Authors: Bin Wang, Ming Jia, Shijie Jia, Jiuhe Wan, Xiao Zhou, Zhimin Luo, Ye Zhou, Jianqun Zhang Tags: Original Articles Source Type: research

Cerebrovascular Events After a Primary Percutaneous Coronary Intervention Strategy for Acute ST-Segment- Elevation Myocardial Infarction: Analysis From the HORIZONS-AMI Trial Coronary Interventions
Conclusions— In HORIZONS-AMI, cerebrovascular events within 3 years after ST-segment–elevation myocardial infarction in patients undergoing a primary percutaneous coronary intervention management strategy occurred in 2.0% of patients and were most frequent after coronary artery bypass grafting. Cerebrovascular events were often disabling and were strongly associated with high rates of death, reinfarction, recurrent ischemia, and major bleeding. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00433966.
Source: Circulation: Cardiovascular Interventions - April 9, 2015 Category: Cardiology Authors: Nikolsky, E., Mehran, R., Dangas, G. D., Xu, K., Parvataneni, R., Witzenbichler, B., Guagliumi, G., Kornowski, R., Genereux, P., Brener, S. J., Stone, G. W. Tags: Catheter-based coronary interventions: stents, Acute myocardial infarction, Acute Stroke Syndromes Source Type: research

Consequence of Ischemic Stroke after Coronary Surgery with Cardiopulmonary Bypass According to Stroke Subtypes
Introduction: The aim of this study was to determine the outcomes of patients developing ischemic stroke after coronary artery bypass grafting (CABG).Methods: From March 2012 to January 2017, 5380 consecutive patients undergoing elective coronary surgery were analyzed. Ninety-five patients who developed ischemic strokes after on-pump coronary surgery were included in the study, retrospectively. The cohort was divided into four subgroups [total anterior circulation infarction (TACI), partial anterior circulation infarction (PACI), posterior circulation infarction (POCI), and lacunar...
Source: Brazilian Journal of Cardiovascular Surgery - November 22, 2018 Category: Cardiology Source Type: research

Compared with matched controls, patients with postoperative atrial fibrillation (POAF) have increased long-term AF after CABG, and POAF is further associated with increased ischemic stroke, heart failure and mortality even after adjustment for AF
ConclusionsPatients with POAF after CABG had three times the incidence of long-term AF compared with both non-POAF patients and matched controls. POAF was associated with long-term ischemic stroke, heart failure, and corresponding mortality even after adjustment for AF during follow-up. The increased overall mortality was partly explained by morbidities associated with POAF.Graphic abstract
Source: Clinical Research in Cardiology - February 7, 2020 Category: Cardiology Source Type: research

Postoperative ischemic stroke and death prediction with CHA2DS2-VASc score in patients having coronary artery bypass grafting surgery: A nationwide cohort study
This nationwide cohort study was attempted to address the predictive role of CHA2DS2-VASc score in both ischemic stroke and death in patients undergoing coronary artery bypass grafting (CABG) surgery.
Source: International Journal of Cardiology - February 11, 2017 Category: Cardiology Authors: Wei-Syun Hu, Cheng-Li Lin Source Type: research

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