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Abstract 166: Developing the Veterans Affairs Cardiac Risk Score Session Title: Poster Session I
Conclusion: We demonstrated that an EHR in a specific population could risk-stratify patients as well those from as organized cohort studies and greatly improve calibration. Further, our finding that the ASCVD score greatly underpredicted in our population, while previous work have reported the ASCVD over-predictind in other cohorts, suggests that rather than arguing about which risk tool is best, our patients may be better served by us focusing on calibrating CV risk tools for our specific patient population using their EHR data.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Sussman, J. B., Wiitala, W., Hofer, T., Zawitowski, M., Vijan, S., Hayward, R. Tags: Session Title: Poster Session I Source Type: research

Does renin‐angiotensin system blockade protect lupus nephritis patients from atherosclerotic cardiovascular events? A case‐control study
Conclusions: Our data do not support the hypothesis that ACEIs/ARBs may be protective against atherosclerotic CVEs in LN patients. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - February 11, 2016 Category: Rheumatology Authors: Konstantinos Tselios, Dafna D Gladman, Jiandong Su, Murray B Urowitz Tags: Original Article Source Type: research

Does Renin ‐Angiotensin System Blockade Protect Lupus Nephritis Patients From Atherosclerotic Cardiovascular Events? A Case–Control Study
ConclusionOur data do not support the hypothesis that ACE inhibitors/ARBs may be protective against atherosclerotic CVEs in LN patients.
Source: Arthritis Care and Research - August 18, 2016 Category: Rheumatology Authors: Konstantinos Tselios, Dafna D. Gladman, Jiandong Su, Murray B. Urowitz Tags: Original Article Source Type: research

Development and Validation of a Cardiovascular Risk Assessment Model in Patients With Established Coronary Artery Disease
In conclusion, in patients with established coronary artery disease, the risk of cardiovascular mortality during longer term follow-up can be adequately predicted using the clinical characteristics available at baseline. However, the prediction of nonfatal outcomes, both separately and combined with fatal outcomes, poses major challenges for clinicians and model developers.
Source: The American Journal of Cardiology - April 3, 2013 Category: Cardiology Authors: Linda Battes, Rogier Barendse, Ewout W. Steyerberg, Maarten L. Simoons, Jaap W. Deckers, Daan Nieboer, Michel Bertrand, Roberto Ferrari, Willem J. Remme, Kim Fox, Johanna J.M. Takkenberg, Eric Boersma, Isabella Kardys Tags: Coronary Artery Disease Source Type: research

Contrast-induced acute kidney injury after primary percutaneous coronary intervention: results from the HORIZONS-AMI substudy
Conclusion Contrast-induced acute kidney injury is associated with poor short- and long-term outcomes after primary percutaneous coronary intervention in STEMI.
Source: European Heart Journal - June 14, 2014 Category: Cardiology Authors: Narula, A., Mehran, R., Weisz, G., Dangas, G. D., Yu, J., Genereux, P., Nikolsky, E., Brener, S. J., Witzenbichler, B., Guagliumi, G., Clark, A. E., Fahy, M., Xu, K., Brodie, B. R., Stone, G. W. Tags: Interventional cardiology Source Type: research

Blood Transfusion and the Risk of Atrial Fibrillation after Cardiac Surgery
ConclusionsPerioperative Tx may be associated with excess AF following CABG. This risk increases with increasing number of Tx.
Source: Journal of Cardiac Surgery - May 1, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Abdallah K. Alameddine, Paul Visintainer, Victor K. Alimov, John A. Rousou Tags: Original Article Source Type: research

Who might benefit from early aspirin after coronary artery surgery?
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether early administration of aspirin might optimize vein graft patency. More than 250 papers were found using the reported search, of which 4 new papers in addition to the previous 7 represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated. Early postoperative aspirin administered within 6 h following coronary artery bypass grafting (CABG) has been show...
Source: Interactive CardioVascular and Thoracic Surgery - August 14, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Gukop, P., Gutman, N., Bilkhu, R., Karapanagiotidis, G. T. Tags: Cardiac - physiology, Education, Congestive Heart Failure, Molecular biology Adult Cardiac Source Type: research

Postoperative Atrial Fibrillation After Thoracic Aortic Surgery
Conclusions Several risk factors contribute to the incidence of POAF after thoracic aortic surgery. We found that POAF significantly increased 30-day operative mortality (p < 0.0001). Our findings can be used to develop a risk stratification system for the prediction of POAF.
Source: The Annals of Thoracic Surgery - December 30, 2014 Category: Cardiovascular & Thoracic Surgery Source Type: research

Outcome of Early Revascularization Surgery in Patients with ST‐Elevation Myocardial Infarction
ConclusionsIn patients with ST‐elevation myocardial infarction who required emergency coronary artery bypass surgery, there was no difference in procedure complications or mortality between early (within 24 hours) or later (more than 24 hours). That was noted at one month and one year after the index myocardial infarction.
Source: Journal of Interventional Cardiology - December 1, 2014 Category: Cardiology Authors: Atif N. Khan, Salah Sabbagh, Sunitha Ittaman, Victor Abrich, Aarti Narayan, Bryan Austin, Shereif H. Rezkalla Tags: Original Investigation Source Type: research

Predictors of Long-term Clinical Endpoints in Patients With Refractory Angina Coronary Heart Disease
Conclusions Clinically stable patients with RA who are medically managed have a modest mortality, but a high incidence of hospitalization and resource use over 3 years. These findings point to the need for novel therapies aimed at symptom mitigation in this population and their potential impact on health care utilization and costs.
Source: JAHA:Journal of the American Heart Association - January 30, 2015 Category: Cardiology Authors: Povsic, T. J., Broderick, S., Anstrom, K. J., Shaw, L. K., Ohman, E. M., Eisenstein, E. L., Smith, P. K., Alexander, J. H. Tags: Coronary Heart Disease Source Type: research

Impact of Ultrafiltration on Kidney Injury After Cardiac Surgery: The Michigan Experience
Conclusions Patients exposed to CUF had a higher adjusted risk of AKI. Clinical teams should consider lower volumes of CUF among patients with low creatinine clearance to minimize the risk of AKI.
Source: The Annals of Thoracic Surgery - July 22, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Impact of Ultrafiltration on Kidney Injury After Cardiac Surgery: The Michigan Experience.
CONCLUSIONS: Patients exposed to CUF had a higher adjusted risk of AKI. Clinical teams should consider lower volumes of CUF among patients with low creatinine clearance to minimize the risk of AKI. PMID: 26209495 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - July 22, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Paugh TA, Dickinson TA, Martin JR, Hanson EC, Fuller J, Heung M, Zhang M, Shann KG, Prager RL, Likosky DS, Michigan Society of Thoracic and Cardiovascular Surgeons and the Perfusion Measures and Outcomes (PERForm) Registry Tags: Ann Thorac Surg Source Type: research

Safety and efficacy of glucose-insulin-potassium treatment in coronary artery bypass graft surgery and percutaneous coronary intervention
The purpose of this meta-analysis was to evaluate protective effects of glucose–insulin–potassium (GIK) on outcomes after coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI). We systematically searched Medline/Pubmed, Elsevier, Embase, Web of Knowledge and Google Scholar. A total of 1206 studies were retrieved during the extensive literature search of all major databases; however, 38 trials reporting the end-point of interest were selected. We performed a pooled analysis of outcomes following PCI: incidence of cardiac arrest [odds ratio (OR) of 0.91; 95% confidence interval (CI): ...
Source: Interactive CardioVascular and Thoracic Surgery - October 19, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Ali-Hassan-Sayegh, S., Mirhosseini, S. J., Zeriouh, M., Dehghan, A. M., Shahidzadeh, A., Karimi-Bondarabadi, A. A., Sabashnikov, A., Popov, A.-F. Tags: Congestive Heart Failure Adult Cardiac Source Type: research

Clinical characteristics, management and 1-year outcomes of patients with acute coronary syndrome in Iran: the Iranian Project for Assessment of Coronary Events 2 (IPACE2)
Conclusions Our study showed that the composition of Iranian patients with ACS regarding the type of ACS is similar to that in developed European countries and is unlike that in developing countries of the Middle East and Africa. We found that our patients with ACS are treated with high levels of adherence to guideline-recommended in-hospital medications.
Source: BMJ Open - December 15, 2015 Category: Journals (General) Authors: Kassaian, S. E., Masoudkabir, F., Sezavar, H., Mohammadi, M., Pourmoghaddas, A., Kojouri, J., Ghaffari, S., Sanaati, H., Alaeddini, F., Pourmirza, B., Mir, E., on-behalf of the IPACE2 registry investigators Tags: Open access, Cardiovascular medicine, Evidence based practice, Medical management Research Source Type: research

Age-dependent trends in postoperative mortality and preoperative comorbidity in isolated coronary artery bypass surgery: a nationwide study ADULT CARDIAC
CONCLUSION Patients are getting older at the time of surgery and have a heavier burden of comorbidities than before. The proportion of patients undergoing urgent or emergency surgery increased with age and over time. Despite this, the 30-day mortality decreased over time and long-term survival increased, except in octogenarians where it was stable. Octogenarians had substantially higher 30-day mortality compared with younger patients but surgery can be performed with acceptable risks and good long-term outcomes.
Source: European Journal of Cardio-Thoracic Surgery - January 13, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Thorsteinsson, K., Fonager, K., Merie, C., Gislason, G., Kober, L., Torp-Pedersen, C., Mortensen, R. N., Andreasen, J. J. Tags: Molecular biology ADULT CARDIAC Source Type: research

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