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Therapy: Palliative
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Total 267 results found since Jan 2013.
Tackling Ischemic Reperfusion Injury With the Aid of Stem Cells and Tissue Engineering
Ischemia is a severe condition in which blood supply, including oxygen (O), to organs and tissues is interrupted and reduced. This is usually due to a clog or blockage in the arteries that feed the affected organ. Reinstatement of blood flow is essential to salvage ischemic tissues, restoring O, and nutrient supply. However, reperfusion itself may lead to major adverse consequences. Ischemia-reperfusion injury is often prompted by the local and systemic inflammatory reaction, as well as oxidative stress, and contributes to organ and tissue damage. In addition, the duration and consecutive ischemia-reperfusion cycles are re...
Source: Frontiers in Physiology - September 17, 2021 Category: Physiology Source Type: research
End of Life Neuropsychological Impairments and Psychological Care of Persons With Advanced Parkinsonism
Am J Hosp Palliat Care. 2021 Oct 4:10499091211049798. doi: 10.1177/10499091211049798. Online ahead of print.ABSTRACTDecline in executive functioning, before frank dementia occurs, has been reported in patients with a history of stroke and malignant brain tumors. This may also be true in patients with advanced Parkinson's disease (PD). In this paper, we summarize the limited research on the motor and cognitive predictors of mortality in advanced PD. We then provide 2 case vignettes of patients with end of life advanced PD who demonstrated a substantial decline in working memory and speech festination. We contrast these pati...
Source: The American Journal of Hospice and Palliative Care - October 5, 2021 Category: Palliative Care Authors: George P Prigatano Naomi Salins Source Type: research
Using the vignette methodology to measure access
ConclusionsThe vignette approach has the potential to identify gaps in coverage and access as well as differences in treatment and quality. Four detailed pilots have provided valuable insights in the challenges and limitations of the method that can be addressed in future applications. These include suggestions to improve user friendliness, scope, expert selection and complementing the survey with more specific and quantitative questions.
Source: The European Journal of Public Health - October 20, 2021 Category: General Medicine Source Type: research
1.I. Workshop: Capturing access challenges in health care: can the vignette methodology help?
Abstract Access to health care is a key performance dimension for health systems. Around 3% of the EU27 population experienced unmet need for health services in 2019 (Eurostat 2021). However, this average hides significant differences across and within countries, between income groups, levels of education and socio-economic categories. While some of the reasons for unmet need are more personal (no time, fear of doctor, etc.), the most common factors are health system-related. Although self-reported unmet need and other existing indicators, including catastrophic spending and impoverishing out-of-pocket spending, provide ...
Source: The European Journal of Public Health - October 20, 2021 Category: General Medicine Source Type: research
Clinical and Imaging Features Associated with the Utilization of Comfort Measures Only in Acute Ischemic Stroke
Journal of Palliative Medicine, Ahead of Print.
Source: Journal of Palliative Medicine - October 26, 2021 Category: Palliative Care Authors: Varun Jain Amreen Farooqui Yoram A. Roman Casul Nandakumar Nagaraja Source Type: research
13 The shock team approach: the rationale and evidence
Cardiogenic shock (CS) is defined as a state of ineffective cardiac output caused by a cardiac disorder that results in both clinical and biochemical manifestations of inadequate tissue perfusion.1 Among patients presenting with CS, there is a spectrum of disease whereby some patients can be stabilised with pharmacologic interventions alone, while others require escalation to mechanical circulatory support (MCS).2 As patients and treatment options both become increasingly complex, comprehensive critical care may be best delivered in disease-specific service line ICUs.2 The model of the cardiac ICU has transitioned over tim...
Source: Heart Asia - April 24, 2019 Category: Cardiology Authors: Kiernan, M. S. Tags: Keynote Lecture Source Type: research
Tube feeding in patients with dementia is associated with a longer palliative care unit stay
CONCLUSION: The present study showed that, in patients with an established diagnosis of dementia, TF is common and independently associated with a longer length of PCU stay. Nevertheless, the study was underpowered and the results deserve confirmation in larger studies.PMID:34971282 | DOI:10.1002/alz.052919
Source: The Journal of Alzheimers Association - December 31, 2021 Category: Psychiatry Authors: Hilal Zengin Ilker Tasci Source Type: research
Multiscale modelling of Potts shunt as a potential palliative treatment for suprasystemic idiopathic pulmonary artery hypertension: a paediatric case study
In conclusion, this model reasonably represents patient-specific haemodynamics pre- and post-creation of the PS, providing insights into physiology of this complex condition, and presents a predictive tool that could be useful for clinical decision-making regarding suitability for PS in PAH patients with drug-resistant suprasystemic PAH.PMID:35000016 | DOI:10.1007/s10237-021-01545-2
Source: Biomechanics and Modeling in Mechanobiology - January 9, 2022 Category: Biomedical Science Authors: Sanjay Pant Aleksander Sizarov Angela Knepper Ga ëtan Gossard Alberto Noferi Younes Boudjemline Irene Vignon-Clementel Source Type: research
Impact of obesity on acute complications of catheter ablation for cardiac arrhythmia.
ConclusionIn this study, obesity did not have a significant impact on the incidence of periprocedural complications after CA for cardiac arrhythmia.This article is protected by copyright. All rights reserved.
Source: Journal of Cardiovascular Electrophysiology - February 4, 2022 Category: Cardiology Authors: Niklas Schenker, Flurina Blumenthal, Samer Hakmi, Christine Lemes, Shibu Mathew, Laura Rottner, Peter Wohlmuth, Bruno Rei ßmann, Andreas Rillig, Andreas Metzner, Stephan Willems, Feifan Ouyang, Karl‐Heinz Kuck, Tilman Maurer Tags: ORIGINAL ARTICLE Source Type: research
A novel nomogram to predict overall survival in head and neck cancer survivors with radiation-induced brain necrosis
CONCLUSION: In this LASSO-Cox model-based nomogram study, we developed and validated an easily applied model to predict overall survival in head and neck cancer survivors following an RN diagnosis.PMID:35121029 | DOI:10.1016/j.radonc.2022.01.033
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - February 5, 2022 Category: Radiology Authors: Dong Pan Xiaoming Rong Yingying Zhu Wai Tong Ng Dongping Chen Honghong Li Yongteng Xu Yamei Tang Radiation Oncology Palliative Care Collaborative Group Source Type: research
