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Specialty: Geriatrics

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Total 1481 results found since Jan 2013.

Older people's attitudes towards resuming driving in the first four months post‐stroke
ConclusionsFor the most part, driving was not a key consideration for participants during this phase of their recovery. Physical restrictions and confidence were seen as the main deterrent to driving post‐stroke; however, this varied according to gender. Driving information is generally not retained in the first four weeks of recovery post‐stroke. This has implications for the content and timing of driving information given post‐stroke.
Source: Australasian Journal on Ageing: - March 1, 2014 Category: Geriatrics Authors: Annabel McNamara, Stacey George, Julie Ratcliffe, Ruth Walker Tags: Research Article Source Type: research

Design considerations for a theory-driven exergame-based rehabilitation program to improve walking of persons with stroke
Abstract Virtual rehabilitation approaches for promoting motor recovery has attracted considerable attention in recent years. It appears to be a useful tool to provide beneficial and motivational rehabilitation conditions. Following a stroke, hemiparesis is one of the most disabling impairments and, therefore, many affected people often show substantial deficits in walking abilities. Hence, one of the major goals of stroke rehabilitation is to improve patients' gait characteristics and hence to regain their highest possible level of walking ability. Because previous studies indicate a relationship between walking ...
Source: European Review of Aging and Physical Activity - December 7, 2013 Category: Geriatrics Source Type: research

Intravenous Thrombolysis for Acute Ischemic Stroke in the Elderly: An Italian Cohort Study in a “Real World” Setting
Conclusion Thrombolysis in patients aged >80 years was not associated with significantly increased intracranial hemorrhage. The higher 3-month disability rate observed in octogenarians may be explained by the more severe stroke and higher poststroke disability. Based on the current, “real world setting” study, we advocate the need for a randomized clinical trial to better clarify the efficacy and safety of intravenous thrombolysis for acute ischemic stroke in the elderly.
Source: International Journal of Gerontology - March 10, 2015 Category: Geriatrics Source Type: research

Can Blood Pressure Be Lowered Safely in Older Adults with Lacunar Stroke? The Secondary Prevention of Small Subcortical Strokes Study Experience
ConclusionExcept for unsteadiness when standing, there was no difference according to age in individuals with lacunar stroke with respect to side effects potentially related to lowering blood pressure. Although the lower SBP target was not associated with lower likelihood of recurrent stroke, these exploratory analyses suggested a possible benefit related to vascular death.
Source: Journal of the American Geriatrics Society - April 6, 2015 Category: Geriatrics Authors: Carole L. White, Jeff M. Szychowski, Pablo E. Pergola, Thalia S. Field, Robert Talbert, Helena Lau, Kalyani Peri, Oscar R. Benavente, Tags: Clinical Investigations Source Type: research

Rehabilitation Outcomes of Patients With Stroke: Effect of Age on Functional Outcome and Discharge Destination
Conclusions: Although functional outcomes of younger patients with stroke were better as compared to the older patients with stroke, at the end of rehabilitation most of our patients regarding age were able to return home independently.
Source: Topics in Geriatric Rehabilitation - April 1, 2015 Category: Geriatrics Tags: Original Articles Source Type: research

Partial loss of the DNA repair scaffolding protein, Xrcc1, results in increased brain damage and reduced recovery from ischemic stroke in mice.
Abstract Oxidative DNA damage is mainly repaired by base excision repair (BER). Previously, our laboratory showed that mice lacking the BER glycosylases 8-oxoguanine glycosylase 1 (Ogg1) or nei endonuclease VIII-like 1 (Neil1) recover more poorly from focal ischemic stroke than wild-type mice. Here, a mouse model was used to investigate whether loss of 1 of the 2 alleles of X-ray repair cross-complementing protein 1 (Xrcc1), which encodes a nonenzymatic scaffold protein required for BER, alters recovery from stroke. Ischemia and reperfusion caused higher brain damage and lower functional recovery in Xrcc1(+/-) mi...
Source: Neurobiology of Aging - April 17, 2015 Category: Geriatrics Authors: Ghosh S, Canugovi C, Yoon JS, Wilson DM, Croteau DL, Mattson MP, Bohr VA Tags: Neurobiol Aging Source Type: research

Ischaemic stroke or TIA in older subjects associated with impaired dynamic blood pressure control in the absence of severe large artery stenosis
Conclusion: subjects reporting hypotensive symptoms at stroke onset have a higher prevalence of borderzone infarction, despite being normotensive or hypertensive at baseline.
Source: Age and Ageing - June 22, 2015 Category: Geriatrics Authors: Ryan, D. J., Kenny, R. A., Christensen, S., Meaney, J. F. M., Fagan, A. J., Harbison, J. Tags: Research Papers Source Type: research

Incidence of stroke and seizure in Alzheimer's disease dementia
Background: the objective of the study was to estimate and compare the incidence rates of ischaemic and haemorrhagic stroke and seizure among cohorts with and without Alzheimer's disease (AD) dementia. Methods: we conducted a retrospective cohort study using electronic medical records (EMRs) from primary care practices that participated in The Health Improvement Network (THIN) in the United Kingdom from 1 January 1990 to 31 July 2009. For each AD-dementia patient, we selected one general population control patient without AD-dementia matched to one AD-dementia patient on year of birth, sex and physician practice. Findings:...
Source: Age and Ageing - June 22, 2015 Category: Geriatrics Authors: Cook, M., Baker, N., Lanes, S., Bullock, R., Wentworth, C., Arrighi, H. M. Tags: Short Reports Source Type: research

Influence of cerebral white matter lesions on the activities of daily living of older patients with mild stroke
ConclusionSevere white matter lesions are a prognostic factor for poor ADL at discharge in older patients with stroke who have mild neurological symptoms. Geriatr Gerontol Int ●●; ●●: ●●–●●.
Source: Geriatrics and Gerontology International - September 1, 2015 Category: Geriatrics Authors: Yutaka Yamashita, Ikuo Wada, Mitsuya Horiba, Kento Sahashi Tags: Original Article: Epidemiology, Clinical Practice and Health Source Type: research

Explanatory factors for the association between depression and long-term physical disability after stroke
Conclusion: the association between depression and physical disability appears to be multifactorial. The use of SSRIs after stroke requires further research.
Source: Age and Ageing - October 26, 2015 Category: Geriatrics Authors: Ayerbe, L., Ayis, S. A., Crichton, S., Rudd, A. G., Wolfe, C. D. A. Tags: Short Reports Source Type: research

Clinical and pathogenic features of ischemic stroke among representatives of different gender and age groups
Abstract A total of 1410 patients with ischemic stroke (IS) of four main clinical and pathogenic subtypes, viz., atherothrombotic, cardioembolic, hemodynamic, and lacunar strokes, were studied. We analyzed the dependence of the pathogenic subtype of the stroke, its background pathologies, and stroke risk factors on the age and gender of the patients. It was found that senior patients were more susceptible to atherothrombotic ischemic strokes and patients of working age more frequently suffered from lacunar and hemodynamic strokes, although cases of atherothrombotic strokes in this age cohort were more often obser...
Source: Advances in Gerontology - December 31, 2015 Category: Geriatrics Source Type: research

Clinical Effectiveness of Board-certificated Physiatrists on Functional Recovery in Elderly Stroke Patients During Convalescence: A Retrospective Cohort Study
Conclusions Our results suggest that clinical management provided to elderly stroke patients by board-certificated physiatrists is associated with good functional improvement. Board certification should be encouraged to improve the quality of rehabilitative management of post-stroke patients.
Source: International Journal of Gerontology - February 16, 2017 Category: Geriatrics Source Type: research

The association of a heart attack or stroke with depressive symptoms stratified by the presence of a close social contact: findings from the National Health and Aging Trends Study Cohort
ConclusionsOlder adults have increased odds of having depressive symptoms following a self‐reported stroke, but only those with no close social contacts had increased odds of depressive symptoms following a heart attack. Social networks may play a role in the mechanisms underlying depression among older adults experiencing certain acute health events. Future work exploring the potential causal relationships suggested here, if confirmed, could inform interventions to alleviate or prevent depression among at risk older adults. Copyright © 2017 John Wiley & Sons, Ltd.
Source: International Journal of Geriatric Psychiatry - February 21, 2017 Category: Geriatrics Authors: Adam Simning, Christopher L. Seplaki, Yeates Conwell Tags: Research Article Source Type: research

Population-based stroke and dementia incidence trends: Age and sex variations
This study explores these trends within demographic subgroups. Methods We analyzed administrative data sources using validated algorithms to calculate stroke and dementia incidence rates from 2002 to 2013. Results For more than 12 years, stroke incidence remained unchanged among those aged 20 to 49 years and decreased for those aged 50 to 64, 65 to 79, and 80+ years by 22.7%, 36.9%, and 37.9%, respectively. Dementia incidence increased by 17.3% and 23.5% in those aged 20 to 49 and 50 to 64 years, respectively, and remained unchanged in those aged 65 to 79 years and decreased by 15.4% in those aged 80+ years. Discussion T...
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 30, 2017 Category: Geriatrics Source Type: research

Potential Value of Impaired Cognition in Stroke Prediction: A U.K. Population ‐Based Study
ConclusionCriteria for MCI, defined using MMSE scores or clinical criteria, can capture individuals at greater stroke risk. The results highlight the need to focus on stroke risk in individuals even with MCI.
Source: Journal of the American Geriatrics Society - April 3, 2017 Category: Geriatrics Authors: Blossom C. M. Stephan, Kathryn Richardson, George M. Savva, Fiona E. Matthews, Carol Brayne, Vladimir Hachinski Tags: Clinical Investigation Source Type: research