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Spectroscopy of reperfused tissue after stroke reveals heightened metabolism in patients with good clinical outcomes
& Mark W Parsons
Source: Journal of Cerebral Blood Flow and Metabolism - December 1, 2014 Category: Neuroscience Authors: Andrew BivardVenkatesh KrishnamurthyPeter StanwellNawaf YassiNeil J SprattMichael NilssonChristopher R LeviStephen DavisMark W Parsons Tags: acute stroke glutamate lactate MR spectroscopy perfusion-weighted MRI reperfusion regeneration and recovery Source Type: research

Postischemic hyperperfusion on arterial spin labeled perfusion MRI is linked to hemorrhagic transformation in stroke
Noriko Salamon & Danny JJ Wang
Source: Journal of Cerebral Blood Flow and Metabolism - March 31, 2015 Category: Neuroscience Authors: Songlin YuDavid S LiebeskindSumit DuaHolly WilhalmeDavid ElashoffXin J QiaoJeffry R AlgerNerses SanossianSidney StarkmanLatisha K AliFabien ScalzoXin LouBryan YooJeffrey L SaverNoriko SalamonDanny JJ Wang Tags: arterial spin labeling (ASL) acute ischemic stroke (AIS) hemorrhagic transformation (HT) hyperperfusion Source Type: research

Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke
chäfers, Lydia M Sorokin, Michael T Kuhlmann & Andreas H Jacobs
Source: Journal of Cerebral Blood Flow and Metabolism - October 30, 2015 Category: Neuroscience Authors: Bastian ZinnhardtThomas VielLydia WachsmuthAlexis VrachimisStefan WagnerHans-Jörg BreyholzAndreas FaustSven HermannKlaus KopkaCornelius FaberFrédéric DolléSabina PappataAnna M PlanasBertrand TavitianMichael SchäfersLydia M SorokinMichael T KuhlmannAn Tags: microglia matrix metalloproteases perfusion positron emission tomography stroke Source Type: research

Noninvasive cerebral oximetry during endovascular therapy for acute ischemic stroke: an observational study
Julian Bösel
Source: Journal of Cerebral Blood Flow and Metabolism - October 30, 2015 Category: Neuroscience Authors: Christian HametnerPredrag StanarcevicSibylle StampflStefan RohdeRoland VeltkampJulian Bösel Tags: acute ischemic stroke medial cerebral artery occlusion near-infrared spectroscopy perfusion regional oxygen saturation thrombectomy Source Type: research

Thrombectomy in stroke of unknown onset, wake up stroke and late presentations: Australian experience from 2 comprehensive stroke centres
This study shows good ‘real world’ outcomes, comparable to published RCTs, in patients with unknown-onset, or late presentation, stroke treated with EVT more than 6 h from stroke onset.
Source: Journal of Clinical Neuroscience - November 8, 2018 Category: Neuroscience Source Type: research

Changes in structure and perfusion of grey matter tissues during recovery from Ischaemic subcortical stroke: a longitudinal MRI study
This study provides the imaging evidence of structural and vascular plasticity after stroke and expands our understanding of neurobiology of stroke recovery.
Source: European Journal of Neuroscience - September 4, 2017 Category: Neuroscience Authors: Xinfeng Yu, Linglin Yang, Ruirui Song, Yerfan Jiaerken, Jun Yang, Min Lou, Quan Jiang, Minming Zhang Tags: Research Report Source Type: research

Identification of embolic stroke in patients with large vessel occlusion: The Chinese embolic stroke score, CHESS
CONCLUSION: CHESS could reliably and independently identify embolic stroke as the cause of large vessel occlusion.PMID:34559949 | DOI:10.1111/cns.13729
Source: CNS Neuroscience and Therapeutics - September 24, 2021 Category: Neuroscience Authors: Lan Hong Longting Lin Gang Li Jianhong Yang Yu Geng Min Lou Mark Parsons Xin Cheng Qiang Dong Source Type: research

Cerebral venous collaterals: a new fort for fighting ischemic stroke?
Publication date: Available online 2 December 2017 Source:Progress in Neurobiology Author(s): Lu-sha Tong, Zhen-ni Guo, Yi-bo Ou, Yan-nan Yu, Xiao-cheng Zhang, Jiping Tang, John H. Zhang, Min Lou Stroke therapy has entered a new era highlighted by the use of endovascular therapy in addition to intravenous thrombolysis. However, the efficacy of current therapeutic regimens might be reduced by their associated adverse events. For example, over-reperfusion and futile recanalization may lead to large infarct, brain swelling, hemorrhagic complication and neurological deterioration. The traditional pathophysiological understand...
Source: Progress in Neurobiology - December 2, 2017 Category: Neuroscience Source Type: research

Reply to “The effects of functional electrical stimulation on upper extremity function and cortical plasticity in chronic stroke patients”
I appreciate the very important and developed suggestions by Dr. Cecatto for our article (). The proposals on the reasons why EMG-controlled FES (EMG–FES) could shift the brain hemispheric-dominant perfusion in our study provided our study further development and progress. The motor output and corresponding muscle and joint proprioceptive feedback may be tightly coupled and coordinated with movement by EMG–FES. As Dr. Cecatto proposed, these neural reorganisation mechanisms should be explored. The sensory components of large afferent fibre activation, proprioceptive input and increased cognitive sensory attention are a...
Source: Clinical Neurophysiology - February 10, 2014 Category: Neuroscience Authors: Yukihiro Hara Tags: Letters to the Editor Source Type: research

Stroke Mechanisms.
Authors: Wong KS, Caplan LR, Kim JS Abstract Recent advances in neuroimaging technologies, such as diffusion weighted magnetic resonance imaging (MRI), perfusion weighted computed tomography (CT)/MRI, MR/CT angiography and Doppler ultrasonography allow us to determine the mechanisms of stroke and transient ischemic attack. In addition, high-resolution vessel wall MRI is nowadays increasingly used to understand the stroke mechanism in patients with intracranial atherosclerosis. Artery to artery embolism, hypoperfusion and the combination of the two are the important stroke mechanisms in patients with extracranial at...
Source: Frontiers of Neurology and Neuroscience - December 15, 2016 Category: Neuroscience Tags: Front Neurol Neurosci Source Type: research

Changes in Structure and Perfusion of Gray Matter Tissues during Recovery from Ischemic Subcortical Stroke: A Longitudinal MRI Study
This article is protected by copyright. All rights reserved.
Source: European Journal of Neuroscience - August 1, 2017 Category: Neuroscience Authors: Xinfeng Yu, Linglin Yang, Ruirui Song, Yerfan Jiaerken, Jun Yang, Min Lou, Quan Jiang, Minming Zhang Tags: Research Report Source Type: research

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