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Total 8464 results found since Jan 2013.

Incidence and Risk Factors of Cerebrovascular Events Following Cardiac Catheterization Stroke
Conclusion In a single-center, retrospective assessment over nearly 20 years, cardiac catheterization-related CVEs were very rare and nearly exclusively ischemic. The independent predictors for these events were found to be the performance of an intervention and those associated with increased atherosclerotic burden, specifically older age, triple vessel disease, and prior stroke. The presence of intracoronary thrombus appears also to raise the risk of procedure-related CVE.
Source: JAHA:Journal of the American Heart Association - November 14, 2013 Category: Cardiology Authors: Korn-Lubetzki, I., Farkash, R., Pachino, R. M., Almagor, Y., Tzivoni, D., Meerkin, D. Tags: Stroke Source Type: research

Early and Continuous Neurologic Improvements after Intravenous Thrombolysis Are Strong Predictors of Favorable Long-term Outcomes in Acute Ischemic Stroke
Background: Intravenously administered tissue plasminogen activator (IV tPA) remains the only approved therapeutic agent for arterial recanalization in acute ischemic stroke (AIS). Considerable proportion of AIS patients demonstrate changes in their neurologic status within the first 24 hours of intravenous thrombolysis with IV tPA. However, there are little available data on the course of clinical recovery in subacute 2- to 24-hour window and its impact. We evaluated whether neurologic improvement at 2 and 24 hours after IV tPA bolus can predict functional outcomes in AIS patients at 3 months.Methods: Data for consecutive...
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2013 Category: Neurology Authors: Leonard LL. Yeo, Prakash Paliwal, Hock L. Teoh, Raymond C. Seet, Bernard PL. Chan, Benjamin Wakerley, Shen Liang, Rahul Rathakrishnan, Vincent F. Chong, Eric YS. Ting, Vijay K. Sharma Tags: Original Articles Source Type: research

Clinical Use of Computed Tomographic Perfusion for the Diagnosis and Prediction of Lesion Growth in Acute Ischemic Stroke
Conclusions: In real-world use, acute imaging with CTP did not predict stroke or DWI lesions with sufficient accuracy. Our findings argue against the use of CTP for screening AIS patients until real-world implementations match the accuracy reported from specialized research centers.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2012 Category: Neurology Authors: Branko N. Huisa, William P. Neil, Ronald Schrader, Marcel Maya, Benedict Pereira, Nhu T. Bruce, Patrick D. Lyden Tags: Original Articles Source Type: research

Addition of Hyperacute MRI Aids in Patient Selection, Decreasing the Use of Endovascular Stroke Therapy Clinical Sciences
Conclusions— Implementation of hyperacute MRI protocol decreases the number of endovascular stroke interventions by half. Further investigation of MRI use for patient selection is warranted.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Wisco, D., Uchino, K., Saqqur, M., Gebel, J. M., Aoki, J., Alam, S., George, P., Newey, C. R., Man, S., Tateishi, Y., McNeil, J., Winfield, M., Cheng-Ching, E., Hui, F. K., Toth, G., Bain, M., Rasmussen, P. A., Masaryk, T., Ruggieri, P., Hussain, M. S. Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Assessment of Arterial Collateralization and Its Relevance to Intra-arterial Therapy for Acute Ischemic Stroke
Evidence from recent randomized controlled studies comparing intra-arterial (IA) therapy with intravenous tissue plasminogen activator highlighted the mismatch between recanalization success and clinical outcomes in patients presenting with acute ischemic stroke. There is emerging interest in the impact of arterial collateralization, as determined by leptomeningeal anastomoses (LMAs), on the treatment outcomes of IA therapy. The system of LMA constitutes the secondary network of cerebral collateral circulation apart from the Circle of Willis. Both anatomic and angiographic studies confirmed significant interindividual vari...
Source: Journal of Stroke and Cerebrovascular Diseases - April 18, 2013 Category: Neurology Authors: Siva Seeta Ramaiah, Peter Mitchell, Richard Dowling, Bernard Yan Tags: Review Articles Source Type: research

Angiographic outcome of endovascular stroke therapy correlated with MR findings, infarct growth, and clinical outcome in the DEFUSE 2 trial
ConclusionThrombolysis in cerebral infarction reperfusion following endovascular therapy for ischemic stroke is highly correlated with magnetic resonance imaging reperfusion, infarct growth, and clinical outcome.
Source: International Journal of Stroke - March 31, 2014 Category: Neurology Authors: Michael P. Marks, Maarten G. Lansberg, Michael Mlynash, Stephanie Kemp, Ryan A. McTaggart, Greg Zaharchuk, Roland Bammer, Gregory W. Albers, Tags: Research Source Type: research

Intravenous Thrombolysis Resulting In Acute Ischemic Stroke Recanalization Can Lead To Cerebral Hyperperfusion Syndrome (P7.123)
Conclusion- Cerebral hyperperfusion syndrome after intravenous thrombolysis in acute ischemic stroke should be suspected in patients that achieve arterial recanalization and develop unexplained new neuropsychiatric manifestations.Disclosure: Dr. Ong has nothing to disclose. Dr. Yeo has nothing to disclose. Dr. Ting has nothing to disclose. Dr. Sinha has nothing to disclose. Dr. Teoh has nothing to disclose. Dr. Chan has nothing to disclose. Dr. Seet has nothing to disclose. Dr. Sharma has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ong, J., Yeo, L., Ting, E., Sinha, A., Teoh, H. L., Chan, B., Seet, C. S., Sharma, V. Tags: Cerebrovascular Disease and Interventional Neurology: Issues in Acute Stroke Treatment Source Type: research

Epidemiology of Moyamoya Disease in Taiwan: A Nationwide Population-Based Study Clinical Sciences
Conclusions— The incidence of moyamoya disease has increased in adults but not in children from 2000 to 2011 in Taiwan. Sex ratio and comorbid conditions differed by age and study period.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Chen, P.-C., Yang, S.-H., Chien, K.-L., Tsai, I.-J., Kuo, M.-F. Tags: Cerebrovascular disease/stroke, Epidemiology Clinical Sciences Source Type: research

Relationship Between Magnetic Resonance Angiography–Diffusion-weighted Imaging Mismatch and Clinical Outcome in Endovascular Treatment for Acute Ischemic Stroke: Subgroup Analysis of the Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism–Japan Registry
Background: The presence or absence of the penumbra area is important when performing reperfusion therapy in patients with acute ischemic stroke. As a predictor of this penumbra area, magnetic resonance angiography (MRA)–diffusion-weighted imaging (DWI) mismatch is attracting attention. The usefulness of MRA–DWI mismatch (MDM) using the DWI–Alberta Stroke Program Early Computed Tomography Score (ASPECTS) in endovascular treatment (EVT) of patients with cerebral large vessel occlusion was evaluated.Methods: Of 1442 patients registered in the Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism–Japan Re...
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2014 Category: Neurology Authors: Ichiro Deguchi, Tomohisa Dembo, Shinichi Yoshimura, Nobuyuki Sakai, Yasushi Okada, Kazuo Kitagawa, Kazumi Kimura, Toshio Hyogo, Hiroshi Yamagami, Yusuke Egashira, Norio Tanahashi Tags: Original Articles Source Type: research

Prediction of recanalization in acute stroke patients receiving intravenous and endovascular revascularization therapy
ConclusionThe overall likelihood of recanalization was the highest in the endovascular group, and higher for intravenous thrombolysis compared with no revascularization therapy. However, our statistical models of recanalization for each individual patient indicate significant variability between treatment options, suggesting the need to include this prediction in the personalized treatment selection.
Source: International Journal of Stroke - June 30, 2014 Category: Neurology Authors: Guangming Zhu, Patrik Michel, Tudor Jovin, James T. Patrie, Wenjun Xin, Ashraf Eskandari, Weiwei Zhang, Max Wintermark Tags: Research Source Type: research

Length of Occlusion Predicts Recanalization and Outcome After Intravenous Thrombolysis in Middle Cerebral Artery Stroke Clinical Sciences
Conclusions— The length of middle cerebral artery occlusion is an independent predictor of successful IV-tPA treatment.
Source: Stroke - June 23, 2014 Category: Neurology Authors: Rohan, V., Baxa, J., Tupy, R., Cerna, L., Sevcik, P., Friesl, M., Polivka, J., Polivka, J., Ferda, J. Tags: Computerized tomography and Magnetic Resonance Imaging, Thrombolysis Clinical Sciences Source Type: research

Routine Clinical Evaluation of Cerebrovascular Reserve Capacity Using Carbogen in Patients With Intracranial Stenosis Clinical Sciences
Conclusions— Carbogen-induced CVR elicited no added adverse events and provided a surrogate marker of cerebrovascular reserve consistent with intracranial vasculopathy.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Donahue, M. J., Dethrage, L. M., Faraco, C. C., Jordan, L. C., Clemmons, P., Singer, R., Mocco, J., Shyr, Y., Desai, A., O'Duffy, A., Riebau, D., Hermann, L., Connors, J., Kirshner, H., Strother, M. K. Tags: Brain Circulation and Metabolism, Other imaging, Risk Factors for Stroke Clinical Sciences Source Type: research

Noncardiogenic Stroke Patients with Metabolic Syndrome Have More Border-zone Infarction and Intracranial Artery Stenosis
Little is known about the clinical character of stroke patients with metabolic syndrome (MetS) in Chinese population. In this hospital-based cross-sectional study, we elucidated the prevalence of MetS among patients with acute noncardiogenic cerebral infarction from south China, the topographic infarction patterns in magnetic resonance imaging, and vascular angiography findings of stroke patients with MetS.
Source: Journal of Stroke and Cerebrovascular Diseases - January 2, 2015 Category: Neurology Authors: Zheng Zhang, Meijuan Xiao, Zusen Ye, Wanli Zhang, Bin Han, Youcheng Li Source Type: research

Endovascular treatment of tandem vascular occlusions in acute ischemic stroke
Conclusions Our study shows preliminary data from three centers on recanalization of tandem occlusions in patients presenting with AIS. There was a preference to revascularize the proximal occlusion using a stent followed by distal recanalization with mechanical thrombectomy, intra-arterial thrombolysis or a combination of these. This approach has low periprocedural complications and can achieve an excellent angiographic and clinical outcome.
Source: Journal of NeuroInterventional Surgery - February 12, 2015 Category: Neurosurgery Authors: Puri, A. S., Kuhn, A. L., Kwon, H.-J., Khan, M., Hou, S. Y., Lin, E., Chueh, J., van der Bom, I. M., Dabus, G., Linfante, I., Gounis, M. J., Wakhloo, A. K. Tags: Ischemic stroke Source Type: research

Carotid stenting and intracranial thrombectomy for treatment of acute stroke due to tandem occlusions with aggressive antiplatelet therapy may be associated with a high incidence of intracranial hemorrhage
Conclusions Primary stenting of the extracranial carotid artery combined with intracranial mechanical thrombectomy can be an effective treatment for tandem occlusions, can be performed with a high rate of technical success, and can achieve good clinical outcomes in selected patients. However, the incidence of SICH may be higher than in other patient populations and may be associated with the use of abciximab and advanced patient age.
Source: Journal of NeuroInterventional Surgery - February 12, 2015 Category: Neurosurgery Authors: Heck, D. V., Brown, M. D. Tags: Ischemic stroke Source Type: research