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Total 8464 results found since Jan 2013.

CHADS2 score/CHA2DS2‐VASc score and major artery occlusion in cardioembolic stroke patients with nonvalvular atrial fibrillation
ConclusionAs the CHADS2 and CHA2DS2‐VASs scores increased, the incidence of concurrent major arterial occlusion, particularly internal carotid artery occlusion, increased in patients with cardioembolic stroke associated with nonvalvular atrial fibrillation.
Source: International Journal of Stroke - January 22, 2014 Category: Neurology Authors: Ichiro Deguchi, Takeshi Hayashi, Yasuko Ohe, Yuji Kato, Takuya Fukuoka, Hajime Maruyama, Yohsuke Horiuchi, Hiroyasu Sano, Yuito Nagamine, Norio Tanahashi Tags: Research Source Type: research

Fatal Multiple Systemic Emboli after Intravenous Thrombolysis for Cardioembolic Stroke
Our objective is to present a case of fatal multiple systemic emboli after intravenous thrombolysis for cardioembolic stroke. A 64-year-old woman with atrial fibrillation was admitted for evaluation of sudden consciousness disturbance, right hemiplegia, and aphasia. Diffusion-weighted imaging showed no early ischemic changes of the brain, and magnetic resonance angiography (MRA) showed occlusion of the left middle cerebral artery (MCA). One hour after initiation of 0.6 mg/kg of intravenous alteplase, the MCA was partially recanalized. Her symptoms disappeared the following day. We began intravenous heparin for secondary pr...
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2013 Category: Neurology Authors: Koji Tanaka, Tomoyuki Ohara, Akiko Ishigami, Yoshihiko Ikeda, Toshinori Matsushige, Tetsu Satow, Hatsue Ishibashi-Ueda, Koji Iihara, Kazunori Toyoda Tags: Case Reports Source Type: research

Iodinated Contrast Does Not Alter Clotting Dynamics in Acute Ischemic Stroke as Measured by Thromboelastography Clinical Sciences
Conclusions— Our data do not support an effect of iodinated contrast agents on clot formation or tPA activity.
Source: Stroke - January 27, 2014 Category: Neurology Authors: McDonald, M. M., Archeval-Lao, J. M., Cai, C., Peng, H., Sangha, N., Parker, S. A., Wetzel, J., Riney, S. A., Cherches, M. F., Guthrie, G. J., Roper, T. C., Kawano-Castillo, J. F., Pandurengan, R., Rahbar, M. H., Grotta, J. C. Tags: Computerized tomography and Magnetic Resonance Imaging, Thrombolysis Clinical Sciences Source Type: research

Collaterals at Angiography and Outcomes in the Interventional Management of Stroke (IMS) III Trial Clinical Sciences
Conclusions— More robust collateral grade was associated with better recanalization, reperfusion, and subsequent better clinical outcomes. These data, from the largest endovascular trial to date, suggest that collaterals are an important consideration in future trial design. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00359424.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Liebeskind, D. S., Tomsick, T. A., Foster, L. D., Yeatts, S. D., Carrozzella, J., Demchuk, A. M., Jovin, T. G., Khatri, P., von Kummer, R., Sugg, R. M., Zaidat, O. O., Hussain, S. I., Goyal, M., Menon, B. K., Al Ali, F., Yan, B., Palesch, Y. Y., Broderick Tags: Pathophysiology, Brain Circulation and Metabolism, Angiography Clinical Sciences Source Type: research

Increasing Use of Computed Tomographic Perfusion and Computed Tomographic Angiograms in Acute Ischemic Stroke From 2006 to 2010 Clinical Sciences
Conclusions— There was a marked increase in the rate of CTA and CTP studies in setting of acute ischemic stroke from 2006 to 2010, and both modalities were associated with increased reperfusion therapy use.
Source: Stroke - March 24, 2014 Category: Neurology Authors: Vagal, A., Meganathan, K., Kleindorfer, D. O., Adeoye, O., Hornung, R., Khatri, P. Tags: Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Interim Recanalization in Acute Ischemic Stroke Patients Selected for Endovascular Treatment by CT Angiography (P4.210)
Conclusions:A relatively high proportion of patients have interim recanalization between CT angiogram and cerebral angiogram in acute ischemic stroke patients selected for endovascular treatment.Disclosure: Dr. Qureshi has nothing to disclose. Dr. Siddiq has nothing to disclose. Dr. Kainth has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Qureshi, M., Siddiq, F., Kainth, D., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Endovascular Source Type: research

Intervention Stroke Assessment Scale for Eligibility in Endovascular Therapy (ISAS-ET) (P4.213)
Conclusion:In conclusion, the ISAS scoring system might help with the assessment of patient qualification for further endovascular treatment. Further prospective studies are warranted.Disclosure: Dr. Haitham has nothing to disclose. Dr. Bashir has nothing to disclose. Dr. Hussain has nothing to disclose. Dr. Misthal has nothing to disclose. Dr. Moussavi has nothing to disclose. Dr. Kirmani has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Haitham, D., Bashir, A., Hussain, M., Misthal, S., Moussavi, M., Kirmani, J. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Endovascular Source Type: research

"No Turn Back Approach" to Reduce Treatment Time for Endovascular Treatment of Acute Ischemic Stroke (P4.214)
Conclusions: The "no turn back approach" appeared to be feasible and reduced the time interval between ED arrival and microcatheter placement in acute ischemic stroke patients undergoing endovascular treatment.Disclosure: Dr. Egila has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Siddiqi has nothing to disclose. Dr. Mian has nothing to disclose. Dr. Hassan has nothing to disclose. Dr. Miley has nothing to disclose. Dr. Rodriguez has nothing to disclose. Dr. Suri has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Egila, H., Adil, M., Siddiqi, H., Mian, N., Hassan, A., Miley, J., Rodriguez, G., Suri, M., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Endovascular Source Type: research

Ischemic Stroke in Evolution: Predictive Value of Perfusion Computed Tomography
Background: Various perfusion computed tomography (PCT) parameters have been used to identify tissue at risk of infarction in the setting of acute stroke. The purpose of this study was to examine predictive value of the PCT parameters commonly used in clinical practice to define ischemic penumbra. The patient selection criterion aimed to exclude the effect of thrombolysis from the imaging data.Methods: Consecutive acute stroke patients were screened and a total of 18 patients who initially underwent PCT and CT angiogram (CTA) on presentation but did not qualify to receive thrombolytic therapy were selected. The PCT images ...
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2013 Category: Neurology Authors: Amir Kheradmand, Marc Fisher, David Paydarfar Tags: Original Articles Source Type: research

“No Turn Back Approach” to Reduce Treatment Time for Endovascular Treatment of Acute Ischemic Stroke
Conclusions: The no turn back approach appeared to be feasible and reduced the time interval between ED arrival and microcatheter placement in acute ischemic stroke patients undergoing endovascular treatment.
Source: Journal of Stroke and Cerebrovascular Diseases - February 21, 2014 Category: Neurology Authors: Adnan I. Qureshi, Hossam Egila, Malik M. Adil, Harris Siddiqi, Nidaullah Mian, Ameer E. Hassan, Jefferson T. Miley, Gustavo J. Rodriguez, M. Fareed K. Suri Tags: Original Articles Source Type: research

Impact of Collaterals on Successful Revascularization in Solitaire FR With the Intention for Thrombectomy Clinical Sciences
Conclusions— Better collaterals were associated with lower glucose, lower blood pressure, smaller baseline infarcts in SWIFT, and greater likelihood of successful revascularization without hemorrhage and good clinical outcomes. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01054560.
Source: Stroke - June 23, 2014 Category: Neurology Authors: Liebeskind, D. S., Jahan, R., Nogueira, R. G., Zaidat, O. O., Saver, J. L., for the SWIFT Investigators Tags: Cerebrovascular disease/stroke, Brain Circulation and Metabolism, Angiography Clinical Sciences Source Type: research

Advantages of susceptibility‐weighted magnetic resonance sequences in the visualization of intravascular thrombi in acute ischemic stroke
ConclusionsSWAN was more sensitive than T2* in the visualization of SVS in the intracranial arteries during the acute phase of ischemic stroke. Our study shows that the low number of SVS visualized using T2* in previous studies is probably related to a lack of sensitivity of the sequence, rather than to the nature or age of the thrombus. The greater sensitivity of SWAN seems to be linked to the visualization of SVS in cases of small thrombi.
Source: International Journal of Stroke - October 1, 2014 Category: Neurology Authors: R. Allibert, C. Billon Grand, F. Vuillier, F. Cattin, E. Muzard, A. Biondi, T. Moulin, E. Medeiros Tags: Short Report Source Type: research

North American Solitaire Stent Retriever Acute Stroke registry: post-marketing revascularization and clinical outcome results
Conclusions The NASA registry demonstrated that the Solitaire FR device performance in clinical practice is comparable with the SWIFT and TREVO 2 trial results.
Source: Journal of NeuroInterventional Surgery - September 5, 2014 Category: Neurosurgery Authors: Zaidat, O. O., Castonguay, A. C., Gupta, R., Sun, C.-H. J., Martin, C., Holloway, W. E., Mueller-Kronast, N., English, J. D., Linfante, I., Dabus, G., Malisch, T. W., Marden, F. A., Bozorgchami, H., Xavier, A., Rai, A. T., Froehler, M. T., Badruddin, A., Tags: Ischemic stroke Source Type: research

Imaging of occlusive thrombi in acute ischemic stroke
Thrombi, or clots, often occlude proximal segments of the cerebral arterial circulation in acute ischemic stroke. Thromboembolic occlusion or thrombi superimposed on atherosclerotic plaque are the principal focus of acute stroke therapies such as thrombolysis or thrombectomy. We review the imaging characteristics of thrombi on multimodal computed tomography and magnetic resonance imaging, angiography, and ultrasonography, summarizing recent studies that facilitate therapeutic decision‐making from these noninvasive studies. Information about the location, size, and imaging characteristics can be ascertained using these te...
Source: International Journal of Stroke - December 26, 2014 Category: Neurology Authors: Gregory G. Gasparian, Nerses Sanossian, Mark S. Shiroishi, David S. Liebeskind Tags: Review Source Type: research

Bright Vessel Appearance on Arterial Spin Labeling MRI for Localizing Arterial Occlusion in Acute Ischemic Stroke Brief Reports
Conclusions— The bright vessel appearance on ASL imaging can provide an important diagnostic clue for the detection and localization of arterial occlusion sites in patients with acute ischemic stroke.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Yoo, R.-E., Yun, T. J., Rhim, J. H., Yoon, B.-W., Kang, K. M., Choi, S. H., Kim, J.-H., Kim, J. E., Kang, H.-S., Sohn, C.-H., Han, M. H. Tags: CT and MRI, Acute Cerebral Infarction, Brain Circulation and Metabolism, Computerized tomography and Magnetic Resonance Imaging Brief Reports Source Type: research