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STEPS-T Program Improves Endovascular Treatment Outcomes of Acute Ischemic Stroke; A 6-Year Study
Conclusions: Significant improvements were observed following the deployment of a quality initiative enabling iterative evidence-based process improvements, thereby sustaining significant reductions in time-to-treat and improved clinical outcomes for AIS patients.
Source: Frontiers in Neurology - February 11, 2020 Category: Neurology Source Type: research

Complete lingual palsy from bilateral Dejerine syndrome (bilateral medial medullary stroke)
A 63-year-old man with several vascular risk factors presented with sudden left hemiplegia rapidly evolving to quadriparesis, dysarthria, bilateral hypoglossal palsy (video 1 on the Neurology® Web site at Neurology.org), and respiratory failure. IV thrombolysis with recombinant tissue plasminogen activator was administered. MRI confirmed bilateral medial medullary infarction (figure, A), and CT and magnetic resonance angiography showed right vertebral artery V4 occlusion, presumably atherosclerotic (figure, B). Tongue mobility recovered completely after 3 months (video 2).
Source: Neurology - July 31, 2016 Category: Neurology Authors: Tsetsou, S., Beuchat, I., Laginha, I., Michel, P. Tags: MRI, Other cerebrovascular disease/ Stroke, Clinical neurology examination, Other Education VIDEO NEUROIMAGES Source Type: research

Stenosis Length and Degree Interact With the Risk of Cerebrovascular Events Related to Internal Carotid Artery Stenosis
Conclusion: We found a statistically insignificant tendency for the ultrasound-measured length of sICAS<70% to be longer than that of sICAS≥70%. Moreover, the ultrasound-measured length of sICAS<90% was significantly longer than that of sICAS 90%. Among patients with sICAS≥70%, the degree and length of stenosis were inversely correlated. Larger studies are needed before a clinical implication can be drawn from these results. Introduction Internal carotid artery stenosis (ICAS) causes around one-fifth of ischemic cerebrovascular stroke and has the highest risk of early stroke recurrence...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research

Correlation Between Intracranial Arterial Calcification and Imaging of Cerebral Small Vessel Disease
Conclusion: Intracranial artery calcification is common in patients with ischemic cerebrovascular disease and the intracranial carotid artery is most frequently affected. Intracranial arterial calcifications might be associated with imaging markers of SVD and are highly correlated with WMHs, lacunes, and CMBs. Quantification of calcification on CT provides additional information on the pathophysiology of SVD. Intracranial arterial calcification could act as a potential marker of SVD. Introduction Atherosclerosis is a systemic vascular process that is considered a major cause of cerebrovascular and cardiovascular di...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Could testing grip strength predict heart disease risk?
Conclusion These are interesting results from a range of very different countries, showing that people with low muscle strength may be at higher risk of dying prematurely than other people. Earlier studies in high-income countries had already suggested that this was the case, but this is the first study to show it holds true across countries from high to low incomes. The study also shows that Europeans, and men from high-income countries, on average, have higher grip strength than people from lower-income countries. Interestingly, women from middle-income regions, such as China and Latin America, had slightly higher muscl...
Source: NHS News Feed - May 14, 2015 Category: Consumer Health News Tags: Heart/lungs Medical practice Source Type: news

E-071 Organization of a Neurointerventional Fellowship Curriculum
The objective of this report is to present a comprehensive three -tier model for a Neurointerventional didactics program. Methods The model divides an annual Neurointerventional didactic curriculum in to three tiers: Introduction to Neurointervention Series: Basic concepts of Neurointervention. Implemented during the first two months of the academic year. Faculty/speaker driven. Total 20 sessions. See Table 1. Neurointervention Core Curriculum: Implemented during months 3 to 12 of the academic year. Faculty/speaker moderated; more interactive. Total 30 sessions. See. Table 2. Neurointervention Advanced Didactics: Period...
Source: Journal of NeuroInterventional Surgery - July 26, 2014 Category: Neurosurgery Authors: Garg, A. Tags: Electronic poster abstracts Source Type: research

Plasma Metal Concentrations and Incident Coronary Heart Disease in Chinese Adults: The Dongfeng-Tongji Cohort
Conclusions: Our study suggested that incident CHD was positively associated with plasma levels of titanium and arsenic, and inversely associated with selenium. Additional research is needed to confirm these findings in other populations. https://doi.org/10.1289/EHP1521 Received: 22 December 2016 Revised: 17 September 2017 Accepted: 19 September 2017 Published: 19 October 2017 Address correspondence to T. Wu, or A. Pan, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hongkong Rd., Wuhan 430030, Hubei, China. Telephone: +86-27-83692347. Email: wut@mails.tjmu.edu.cn or p...
Source: EHP Research - October 20, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Growth, not just size, boosts brain aneurysms' risk of bursting
Brain aneurysms of all sizes — even small ones the size of a pea — are up to 12 times more likely to rupture if they are growing, according to a new UCLA study.   Published July 2 in the online edition of the journal Radiology, the discovery counters current guidelines suggesting that small aneurysms pose a low risk for rupture, and it emphasizes the need for regular monitoring and earlier treatment.   "Until now, we believed that large aneurysms presented the highest risk for rupture and that smaller aneurysms may not require monitoring," said lead author Dr. J. Pablo Villablanca, chief of diagn...
Source: UCLA Newsroom: Health Sciences - July 2, 2013 Category: Universities & Medical Training Source Type: news

Intracranial artery stenosis and progression from mild cognitive impairment to Alzheimer disease
Conclusions: Intracranial arterial stenosis increased the risk of developing AD dementia after MCI.
Source: Neurology - March 10, 2014 Category: Neurology Authors: Zhu, J., Wang, Y., Li, J., Deng, J., Zhou, H. Tags: All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia, Alzheimer's disease, MCI (mild cognitive impairment) ARTICLE Source Type: research

Current procedural terminology; a primer
In 1966, The American Medical Association (AMA) working with multiple major medical specialty societies developed an iterative coding system for describing medical procedures and services using uniform language, the Current Procedural Terminology (CPT) system. The current code set, CPT IV, forms the basis of reporting most of the services performed by healthcare providers, physicians and non-physicians as well as facilities allowing effective, reliable communication among physician and other providers, third parties and patients. This coding system and its maintenance has evolved significantly since its inception, and now ...
Source: Journal of NeuroInterventional Surgery - March 12, 2015 Category: Neurosurgery Authors: Hirsch, J. A., Leslie-Mazwi, T. M., Nicola, G. N., Barr, R. M., Bello, J. A., Donovan, W. D., Tu, R., Alson, M. D., Manchikanti, L. Tags: Socioeconomics Source Type: research

Abstract 323: Standardized Triggers for Catheterization Laboratory Morbidity and Mortality Case Review Session Title: Poster Session III
Conclusions: We present a 10-year experience with the use of objective triggers to identify cases for M&M review. This method identifies challenging cases of educational value and could be immediately implemented to strengthen national catheterization laboratory quality improvement programs.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Doll, J. A., Patel, M. R., Sketch, M. H., Harrison, J. K., Tcheng, J. E. Tags: Session Title: Poster Session III Source Type: research

Answers to Epilogue questions
AnswersQuestion 1: C Unenhanced CT examination of the brain revealed extensive thrombosis in the superior sagittal, straight and left transverse sinuses (figure 1). The CT angiogram (figure 2) confirmed venous thrombosis and an arterial infarct. It revealed complete occlusion of left internal carotid artery and segmental vasculopathy, affecting multiple intracranial and extracranial vessels of both the anterior and posterior circulation along with an aneurysmal ascending aorta. The contrast-enhanced CT scan demonstrated a filling defect of the superior sagittal sinus with minimal peripheral contrast enhancement, known as t...
Source: Archives of Disease in Childhood - Education and Practice - May 17, 2016 Category: Pediatrics Authors: Mundada, V., Krishnakumar, D., Chitre, M., Das, T. Tags: Journalology, Eye Diseases, Stroke, Diet, Ophthalmology, Child and adolescent psychiatry (paedatrics), Radiology, Disability, Rheumatology, Dermatology, Clinical diagnostic tests, Radiology (diagnostics), Competing interests (ethics), Metabolic disorders Source Type: research

Rupture of vertebral artery dissection aneurysm during 3D DSA
A 60-year-old man with a history of headache and vomiting had a subarachnoid hemorrhage on CT scan. On 2-dimensional (2D) digital subtraction angiography (DSA), a possible dissection aneurysm of the vertebral artery was seen (video 1 on the Neurology® Web site at Neurology.org). During 3D DSA, the aneurysm suddenly ruptured (video 2), with intracranial hemorrhage. The pressure of contrast was 200 psi, the rate was 2 mL/s, with a total volume of 12 mL. The patient was transferred to the intensive care unit but died of brain herniation and vasospasm. Few dissection aneurysms rupture during 3D DSA, but the risk is likely ...
Source: Neurology - July 10, 2016 Category: Neurology Authors: Xu, D., Wang, C., Zhang, C., Xiang, S., Xie, X. Tags: All Imaging, All Clinical Neurology, All Cerebrovascular disease/Stroke, Critical care, All Education VIDEO NEUROIMAGES Source Type: research

Three-dimensional modeling of Eagle syndrome
A 63-year-old man presented with transient episodes of left-hand weakness and right-eye vision loss following a lengthy airplane trip. The patient had reported right neck pain after sleeping awkwardly on the flight. Carotid dissection, paradoxical embolism, atherosclerotic occlusion, and thrombotic occlusion were considered possible etiologies of the associated carotid occlusion. Following a period of anticoagulation, a subsequent CT angiography (figure 1, A–C) revealed findings consistent with the styloid-carotid artery, or Eagle, syndrome.1 A 3-dimensional model was subsequently created (figure 2, A and B) utilizin...
Source: Neurology - November 20, 2016 Category: Neurology Authors: Shah, K., Miller, D. J. Tags: All Headache, All Clinical Neurology, All Cerebrovascular disease/Stroke, All Education NEUROIMAGES Source Type: research

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