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Clinical Improvement Following Stroke Promptly Reverses Post-stroke Cellular Immune Alterations
Conclusions: SIIA are detectable on admission of acute stroke patients. While it was assumed that post-stroke immunosuppression is rapidly reversed with improvement this is the first data set that shows that improvement actually is associated with a rapid reversal of SIIA demonstrating that SIIA require a constant signal to persist. The observation that HMGB-1 serum concentrations were similar in improved and non-improved cohorts argues against a role for this pro-inflammatory mediator in the maintenance of SIIA. Serum miRNA observed to be regulated in stroke in other publications was counter regulated with improvement in ...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

Summary of evidence-based guideline: Periprocedural management of antithrombotic medications in patients with ischemic cerebrovascular disease: Report of the Guideline Development Subcommittee of the American Academy of Neurology
Objective: To assess evidence regarding periprocedural management of antithrombotic drugs in patients with ischemic cerebrovascular disease. The complete guideline on which this summary is based is available as an online data supplement to this article. Methods: Systematic literature review with practice recommendations. Results and recommendations: Clinicians managing antithrombotic medications periprocedurally must weigh bleeding risks from drug continuation against thromboembolic risks from discontinuation. Stroke patients undergoing dental procedures should routinely continue aspirin (Level A). Stroke patients underg...
Source: Neurology - May 27, 2013 Category: Neurology Authors: Armstrong, M. J., Gronseth, G., Anderson, D. C., Biller, J., Cucchiara, B., Dafer, R., Goldstein, L. B., Schneck, M., Messe, S. R. Tags: Ultrasound, All Medical/Systemic disease, All Neuro-ophthalmology, All Cerebrovascular disease/Stroke, All Trauma SPECIAL ARTICLE Source Type: research

Stroke Patients Likely Safe To Continue Blood Thinners Before Minor Surgery
A new guideline from the American Academy of Neurology advises that it is likely safe for patients to continue taking blood thinners like aspirin or warfarin before minor procedures such as a cataract operation, minor dental surgery or dermatological procedure. Developed with financial support from the American Academy of Neurology, the guideline appears in the 28 May issue of Neurology, the Academy's official journal...
Source: Health News from Medical News Today - May 30, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Factors influencing nonadministration of thrombolytic therapy in early arrival strokes in a university hospital in Hyderabad, India
Conclusion: One-fourth of early ischemic stroke patients in our study were not thrombolyzed even though they arrived within the window period. The majority of the reasons for nonadministration of thrombolysis were potentially preventable, such as nonaffordability, intrahospital delay, and nonavailability of newer endovascular interventions.
Source: Annals of Indian Academy of Neurology - July 24, 2016 Category: Neurology Authors: Lalitha Pidaparthi Anitha Kotha Venkat Reddy Aleti Abhijeet Kumar Kohat Mridula R Kandadai Suryaprabha Turaga Jabeen A Shaik Suvarna Alladi Meena A Kanikannan Borgohain Rupam Subhash Kaul Source Type: research

Statin use linked to small increase in cataracts risk
Conclusion This research using a large cohort of people from a military healthcare system finds that overall, use of statins for over 90 days was associated with a slight increase in a person’s risk of developing cataracts. Further analyses suggested that the risk was higher among people who did not have any additional diseases. From this the researchers suggest that risk may be higher when statins are given for what is called primary prevention, i.e. given to people with risk factors for cardiovascular disease but who have not yet suffered any cardiovascular disease events such as a heart attack or stroke. The study h...
Source: NHS News Feed - September 20, 2013 Category: Consumer Health News Tags: Medication Older people Heart/lungs Source Type: news

Is It Safe To Get A Massage? Dr. Mallika Marshall Answers Your Coronavirus Questions
BOSTON (CBS) – Dr. Mallika Marshall is answering your coronavirus-related medical questions. If you have a question for Dr. Mallika, email her or message her on Facebook or Twitter. Dr. Mallika is offering her best advice, but as always, consult your personal doctor before making any decisions about your personal health. “Is it safe to get a massage from a professional masseuse if both the masseuse and I are wearing a mask? Would getting a massage outdoor be safer?” – Harry It would be safer to get a massage outdoors. That would be amazing, but probably not an option for most people. I would hold off if yo...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 24, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Covid-19 Boston, MA Health Healthcare Status Healthwatch Seen On WBZ-TV Syndicated Local Uncategorized Coronavirus Source Type: news

Coordinating care for people with long term conditions and dementia: room for improvement
New evidence shows that almost one fifth of people with dementia also have other serious conditions such as stroke, diabetes and visual impairment. Services are not currently designed to provide adequate integrated care for people with dementia plus other conditions. For instance, people with dementia are less likely to get diabetes checks or cataract surgery than those without dementia. Carers are not routinely contacted, and there is a lack of guidance for health professionals covering more than one condition. Implications for practice include incorporating the impact of a diagnosis of dementia on pre-existing conditions...
Source: Current Awareness Service for Health (CASH) - July 12, 2016 Category: Consumer Health News Source Type: news

Ischemic Optic Neuropathy in Cardiac Surgery Incidence and Risk Factors in the United States from the National Inpatient Sample 1998 to 2013
Conclusions The incidence of ischemic optic neuropathy in cardiac surgery did not change during the study period. Development of ischemic optic neuropathy after cardiac surgery is associated with carotid artery stenosis, stroke, and degenerative eye conditions.
Source: Anesthesiology - April 18, 2017 Category: Anesthesiology Source Type: research

Novel protein constituents of pathological ocular pseudoexfoliation syndrome deposits identified with mass spectrometry.
Conclusions: This study expands the understanding of the protein composition of pathological PEX material deposited on the ocular lens in patients with PEX syndrome and provides useful insights into the pathophysiology of this disease. This study together with the previous study by our group (Sharma et al. Experimental Eye Research 2009;89(4):479-85) demonstrate that using neat PEX material, devoid of the underlying lens capsule, for proteomics analysis is an effective approach for deciphering the protein composition of complex and highly insoluble extracellular pathological ocular deposits present in patients with PEX syn...
Source: Molecular Vision - February 6, 2019 Category: Molecular Biology Tags: Mol Vis Source Type: research

A Case of Diagnosis of Occipital Lobe Epilepsy Complicated by Right Hemianopsia Associated with Left Occipital Lobe Cerebral Infarction
We report a case of occipital lobe epilepsy (OLE) in a patient with occipital lobe stroke whose diagnosis was complicated by homonymous hemianopsia. An 81-year-old woman presented with a complaint of “blurred vision” on the right side and was kept under outpatient observation at the Hirabayashi Eye Clinic for homonymous lower right hemianopsia, glaucoma, and post-cataract surgery. Her past medical history included hypertension, angina pectoris, atrial fibrillation, diabetes mellitus, and lef t occipital lobe cerebral infarction. The corrected visual acuity and intraocular pressure were 20/16 and 12 mm Hg and 20/20 and ...
Source: Case Reports in Ophthalmology - March 17, 2022 Category: Opthalmology Source Type: research

Extreme face-to-face positioning for cataract surgery with patient seated upright in motorized wheelchair
We present a case of extreme positioning for cataract surgery. The 68-year-old man was unable to lie flat and found it difficult to transfer from his motorized wheelchair. He had poor mobility due to a stroke, slept upright because of orthopnea, and his neck extension was poor. After the options and risks were discussed, surgery was performed under topical intracameral anesthesia using face-to-face positioning with the patient seated upright in his wheelchair. The operating microscope was rotated toward the horizontal, and the surgeon stood at the patient's side with the patient's face almost upright. The right-handed sur...
Source: Journal of Cataract and Refractive Surgery - March 4, 2013 Category: Opthalmology Authors: Mykolas Pajaujis, Anas Injarie, Tom Eke Tags: Case Reports Source Type: research

Safe for stroke patients to continue blood thinners before minor surgical procedures
(Loyola University Health System) It is is likely safe to continue taking blood thinners before minor procedures such as dental procedures, cataract surgery or dermatologic procedures, according to a new guideline from the American Academy of Neurology.
Source: EurekAlert! - Medicine and Health - May 29, 2013 Category: Global & Universal Source Type: news

Prevalence and risk factors of dry eye disease in a British female cohort.
CONCLUSIONS: DED is common and increases with age within this cohort of female twins. We confirmed established risk factors for the first time in a British population, and found important risk factors that might relate to an underlying aetiology involving chronic pain predisposition or somatisation. PMID: 25185440 [PubMed - as supplied by publisher]
Source: The British Journal of Ophthalmology - September 3, 2014 Category: Opthalmology Authors: Vehof J, Kozareva D, Hysi PG, Hammond CJ Tags: Br J Ophthalmol Source Type: research

Self-reported cataracts in older adults in Ghana: sociodemographic and health related factors
Conclusions: Cataract is prevalent in older people in Ghana with approximately 1 in 20 people aged 50 years or older reporting a previous diagnosis of cataract. As cataract surgery is restorative, a public health approach on behavioural modification, well structured national outreach eye care services (for rural residents), inclusion of basic eye health services at sub-district levels, increased family support and national health insurance for older persons is indicated.
Source: Epidemiologic Perspectives and Innovations - September 12, 2014 Category: Epidemiology Authors: Alfred E YawsonEdith M Ackuaku-DogbeNana A SeneadzaGeorge MensahNadia MinicuciNirmala NaidooSomnath ChatterjiPaul KowalRichard B Biritwum Source Type: research

Prevalence and risk factors of dry eye disease in a British female cohort
Conclusions DED is common and increases with age within this cohort of female twins. We confirmed established risk factors for the first time in a British population, and found important risk factors that might relate to an underlying aetiology involving chronic pain predisposition or somatisation.
Source: British Journal of Ophthalmology - November 14, 2014 Category: Opthalmology Authors: Vehof, J., Kozareva, D., Hysi, P. G., Hammond, C. J. Tags: Lens and zonules, Press releases, Neurology Original articles - Clinical science Source Type: research

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