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Procedure: Heart Transplant

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Total 1298 results found since Jan 2013.

Slope in preload recruitable stroke work relationship predicts survival after left ventriculoplasty and mitral repair in patients with idiopathic cardiomyopathy.
CONCLUSIONS: Mw, the slope in the PRSW relationship, may predict survival after LVP and MVP in patients with idiopathic DCM. PMID: 24954287 [PubMed - as supplied by publisher]
Source: Journal of Cardiology - June 18, 2014 Category: Cardiology Authors: Shingu Y, Kubota S, Wakasa S, Ooka T, Kato H, Tachibana T, Matsui Y Tags: J Cardiol Source Type: research

Anticoagulation Reversal With 4-Factor Prothrombin Complex Concentrate in Left Ventricular Assist Device Patients With Acute Hemorrhagic Stroke
Anticoagulation reversal in patients with left ventricular assist devices (LVAD) after acute hemorrhagic stroke must occur rapidly to prevent hemorrhage expansion and limit neurologic sequelae, keeping in mind the risk of thrombotic complications. The purpose of this study was to report a case series of our initial experience using a recently FDA approved (April 2013) 4-factor prothrombin complex concentrate (4F-PCC) for INR normalization after acute hemorrhagic stroke in LVAD patients, and compare the results with traditional INR reversal agents.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: P. Chen, J. Falvey, L. Lowenstein, A. Miranpuri, W. Hallinan, T. Massey Source Type: research

Impact of a Modified Anti-Thrombotic Protocol on the Risk of Stroke and Thromboembolism in Children Supported With the Berlin Heart Excor Pediatric Ventricular Assist Device
Stroke is the most recognized complication associated with the Berlin Heart EXCOR® Pediatric ventricular assist device (VAD). We sought to determine whether a modified anti-thrombotic protocol, involving more intense platelet inhibition and less reliance on Thromboelastrography/ Platelet Mapping™ (TEG/PM), is associated with a lower incidence of stroke.
Source: The Journal of Heart and Lung Transplantation - April 1, 2015 Category: Transplant Surgery Authors: C.A. Lancaster, C.S. Almond, S.A. Hollander, M.L. Stein, A. Lin, L. Doan, J. Murray, D.N. Rosenthal Source Type: research

Gender differences in the risk of stroke during support with continuous flow left ventricular assist device
There is increasing recognition that the risk of stroke after left ventricular assist device (LVAD) varies based on gender, with a higher risk in female patients. We reviewed our own data to determine gender differences in the risk of stroke.
Source: The Journal of Heart and Lung Transplantation - September 3, 2015 Category: Transplant Surgery Authors: Alanna A. Morris, Ann Pekarek, Kris Wittersheim, Robert T. Cole, Divya Gupta, Duc Nguyen, S. Raja Laskar, Javed Butler, Andrew Smith, J. David Vega Source Type: research

Gender differences in the risk of stroke during support with continuous-flow left ventricular assist device
There is increasing recognition that the risk of stroke after left ventricular assist device (LVAD) implantation varies based on gender, with a higher risk in female patients. We reviewed our own data to determine gender differences in the risk of stroke.
Source: The Journal of Heart and Lung Transplantation - September 3, 2015 Category: Transplant Surgery Authors: Alanna A. Morris, Ann Pekarek, Kris Wittersheim, Robert T. Cole, Divya Gupta, Duc Nguyen, S. Raja Laskar, Javed Butler, Andrew Smith, J. David Vega Tags: Original Clinical Science Source Type: research

Relationship Between Anticoagulation Intensity and Thrombotic or Bleeding Outcomes Among Outpatients With Continuous-Flow Left Ventricular Assist Devices Original Articles
Conclusions— INR is inversely related to thrombotic events occurring outside of the hospital among patients supported with CF-LVADs. INR values <2.0 increase the rate of thrombotic events occurring outside of the hospital among patients supported with CF-LVADs.
Source: Circulation: Heart Failure - May 5, 2016 Category: Cardiology Authors: Nassif, M. E., LaRue, S. J., Raymer, D. S., Novak, E., Vader, J. M., Ewald, G. A., Gage, B. F. Tags: Heart Failure, Anticoagulants, Transplantation, Intracranial Hemorrhage, Ischemic Stroke Original Articles Source Type: research

New Cell Adhesion Molecules in Human Ischemic Cardiomyopathy. < i > PCDHGA3 < /i > Implications in Decreased Stroke Volume and Ventricular Dysfunction
Conclusions Our results support the importance of intercalated disks molecular alterations, closely involved in the contractile function, highlighting its crucial significance and showing gene expression changes not previously described. Specifically, altered PCDHGA3 gene expression was strongly associated with reduced stroke volume and ventricular dysfunction in ICM, suggesting a relevant role in hemodynamic perturbations and cardiac performance for this unexplored protocadherin.
Source: PLoS One - July 28, 2016 Category: Biomedical Science Authors: Ana Ortega Source Type: research

Does Type of Mechanical Circulatory Support Influence Stroke Risk in the Perioperative Post Transplant Period?
This study was undertaken to assess if the type of circulatory support device used has an impact on stroke risk in this population.
Source: The Journal of Heart and Lung Transplantation - March 25, 2017 Category: Transplant Surgery Authors: N. Nair, S. Yang, E. Gongora Source Type: research

(1205) Does Stroke in the Perioperative Post Cardiac Transplant Period Impact Survival?
This study addresses the effect of stroke on overall survival in this population.
Source: The Journal of Heart and Lung Transplantation - March 25, 2017 Category: Transplant Surgery Authors: N. Nair, S. Yang, E. Gongora Source Type: research

Five-Year Follow-Up on Transplanted Organs From Donors After Brain Death After Acute Stroke.
CONCLUSIONS: The 5-year follow-up showed that organs from 14 brain-dead donors improved and saved 19 lives, with 17 patients receiving kidney transplants and 2 patients receiving liver transplants. Another 7 patients had only partially improved quality of life. PMID: 28447929 [PubMed - as supplied by publisher]
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 27, 2017 Category: Transplant Surgery Authors: Spatenkova V, Pokorna E, Suchomel P Tags: Exp Clin Transplant Source Type: research

Impact of a Modified Anti-Thrombotic Guideline On Stroke In Children Supported with A Pediatric Ventricular Assist Device
Stroke is the most feared complication associated with the Berlin Heart EXCOR ® Pediatric ventricular assist device (VAD), the most commonly used VAD in children, and affects one in three children. We sought to determine whether a modified anti-thrombotic guideline, involving more intense platelet inhibition and less reliance on platelet function testing, is associated with a lower incidence of stroke.
Source: The Journal of Heart and Lung Transplantation - May 20, 2017 Category: Transplant Surgery Authors: David N. Rosenthal, Chacy A. Lancaster, Doff B. McElhinney, Sharon Chen, MaryLyn Stein, Aileen Lin, Lan Doan, Jenna M. Murray, Mary Alice Gowan, Katsuhide Maeda, Olaf Reinhartz, Christopher S. Almond Source Type: research

ESRD After Heart Failure, Myocardial Infarction, or Stroke in Type  2 Diabetic Patients With CKD
Conclusions Most ESRD cases occurred in individuals without intercurrent CV events who had lower eGFRs than individuals with intercurrent CV events, but similar post-ESRD mortality. Nevertheless, intercurrent CV events, particularly heart failure, are strongly associated with risk for ESRD. These findings underscore the need for kidney-specific therapies in addition to treatment of CV risk factors to lower ESRD incidence in diabetes.
Source: American Journal of Kidney Diseases - June 7, 2017 Category: Urology & Nephrology Source Type: research

Early stroke post –heart transplant is associated with decreased survival in children
In this study we aimed to characterize early MNEs (stroke, isolated seizures not from stroke and posterior reversible leukoencephalopathy [PRES] within 1 year after primary pediatric HTx) and evaluate their impact on 1-year post-HTx survival. We hypothesized that early an MNE after HTx is associated with decreased 1-year patient survival.
Source: The Journal of Heart and Lung Transplantation - January 8, 2018 Category: Transplant Surgery Authors: Cheryl Cammock, Swati Choudhry, Chesney M. Castleberry, Noor Al-Hammadi, Pirooz Eghtesady, Charles E. Canter, Kathleen E. Simpson Tags: Original Clinical Science Source Type: research

Stroke Patterns and Implications for Ventricular Functional Remodeling in Left Ventricular Assist Systems
Ischemic stroke-related complications (particularly in the right hemisphere) are frequently encountered with Left Ventricular Assist Systems (LVAS). The neuro-cardiac axis may influence ventricular remodeling. However it remains unknown if stroke patterns are related to ventricular remodeling after facilitated hemodynamic support with LVAS. We hypothesized that strokes occurring in the right hemisphere, within the insula region, may enhance left ventricular remodeling through unopposed activation of the left insular region.
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: D.F. Snipelisky, P. Ivak, G. Stewart, M. Givertz, M. Pfeffer, J. Groarke, S. Singh, I. Netuka, M. Mehra Source Type: research

Clinical Profile of Patients with Late Stroke after Left Ventricular Assist Device Implantation
Despite advances in left ventricular assist device (LVAD) therapy, stroke remains a relatively frequent complication and is associated with significant morbidity and mortality. In the early postoperative period, stroke may be related to patient demographics, operative factors and comorbid conditions. Less is known about strokes that occur greater than six months after LVAD implantation. The aim of this study was to describe the clinical profile of patients with late strokes.
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: J. Nnanabu, D. Rodgers, N. Sarswat, J. Raikhelkar, G. Kim, S. Kalantari, T. Ota, T. Song, C. Juricek, V. Jeevanandam, G. Sayer, N. Uriel Source Type: research