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Specialty: Neurology
Procedure: SPECT

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Total 97 results found since Jan 2013.

Teaching NeuroImages: Drug-induced parkinsonism with asymmetrical putaminal DaT binding
A 64-year-old patient developed shuffling gait and postural instability over 8 months, in parallel to risperidone intake. Examination showed symmetric parkinsonian syndrome and mild left hemiparesis with spasticity, related to right middle cerebral artery stroke 10 years before. Within 1 month of risperdone withdrawal, parkinsonism disappeared, confirming drug-induced etiology. While degenerative parkinsonism is associated with reduction in striatal dopamine transporters binding in absence of structural lesions to basal ganglia, binding in drug-induced parkinsonism is normal.1 In our case, SPECT anomaly was incidental, rel...
Source: Neurology - May 18, 2015 Category: Neurology Authors: Bridel, C., Garibotto, V. Tags: MRI, SPECT, Parkinson's disease/Parkinsonism, Basal ganglia RESIDENT AND FELLOW SECTION Source Type: research

White Matter Perivascular Spaces on Magnetic Resonance Imaging: Marker of Cerebrovascular Amyloid Burden? Brief Reports
Conclusions— This pilot study suggests a possible association between cerebrovascular amyloid deposition and CSO-PVS, with potential pathophysiological implications.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Charidimou, A., Hong, Y. T., Jager, H. R., Fox, Z., Aigbirhio, F. I., Fryer, T. D., Menon, D. K., Warburton, E. A., Werring, D. J., Baron, J.-C. Tags: PET and SPECT, Intracerebral Hemorrhage Brief Reports Source Type: research

Refractory status epilepticus due to SMART syndrome
Conclusions Taking into account clinical evolution and ictal neuroimaging studies, status epilepticus could explain the origin of these episodes in SMART syndrome. Although most patients have reversible symptoms, in some cases, aggressive treatment to avoid sequelae is needed. This article is part of a Special Issue entitled “Status Epilepticus”.
Source: Epilepsy and Behavior - June 12, 2015 Category: Neurology Source Type: research

Refractory status epilepticus due to SMART syndrome.
CONCLUSIONS: Taking into account clinical evolution and ictal neuroimaging studies, status epilepticus could explain the origin of these episodes in SMART syndrome. Although most patients have reversible symptoms, in some cases, aggressive treatment to avoid sequelae is needed. This article is part of a Special Issue entitled "Status Epilepticus". PMID: 26071996 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - June 11, 2015 Category: Neurology Authors: Jaraba S, Puig O, Miró J, Velasco R, Castañer S, Rodríguez L, Izquierdo C, Simó M, Veciana M, Falip M Tags: Epilepsy Behav Source Type: research

Increase in 18F-Fluoroacetate Uptake in Patients With Chronic Hemodynamic Cerebral Ischemia Brief Reports
Conclusions— In patients with atherosclerotic internal carotid artery or middle cerebral artery disease, 18F-FACE uptake is increased in the noninfarcted cerebral cortex with chronic hemodynamic ischemia characterized by misery perfusion with decreased oxygen metabolism. Increased 18F-FACE uptake may indicate the cortical regions that are at particular risk for ischemic damage.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Yamauchi, H., Kagawa, S., Kishibe, Y., Takahashi, M., Nishii, R., Mizuma, H., Takahashi, K., Onoe, H., Higashi, T. Tags: PET and SPECT Brief Reports Source Type: research

Arterial Spin Labeling Perfusion Magnetic Resonance Image with Dual Postlabeling Delay: A Correlative Study with Acetazolamide Loading I-Iodoamphetamine Single-Photon Emission Computed Tomography
Perfusion magnetic resonance image with arterial spin labeling (ASL) provides a completely noninvasive measurement of cerebral blood flow (CBF). However, arterial transient times can have a marked effect on the ASL signal. For example, a single postlabeling delay (PLD) of 1.5 seconds underestimates the slowly streaming collateral pathways that maintain the cerebrovascular reserve (CVR). To overcome this limitation, we developed a dual PLD method.
Source: Journal of Stroke and Cerebrovascular Diseases - September 16, 2015 Category: Neurology Authors: Sei Haga, Takato Morioka, Takafumi Shimogawa, Tomoaki Akiyama, Kei Murao, Yuka Kanazawa, Tetsuro Sayama, Shuji Arakawa Source Type: research

Imaging Inflammation in Cerebrovascular Disease Topical Reviews
Source: Stroke - September 28, 2015 Category: Neurology Authors: Gounis, M. J., van der Marel, K., Marosfoi, M., Mazzanti, M. L., Clarencon, F., Chueh, J.-Y., Puri, A. S., Bogdanov, A. A. Tags: Cardiovascular imaging agents/Techniques, Computerized tomography and Magnetic Resonance Imaging, PET and SPECT, Other imaging Topical Reviews Source Type: research

Apraxic agraphia following thalamic damage: Three new cases.
Abstract Apraxic agraphia (AA) is a so-called peripheral writing disorder following disruption of the skilled movement plans of writing while the central processes that subserve spelling are intact. It has been observed in a variety of etiologically heterogeneous neurological disorders typically associated with lesions located in the language dominant parietal and frontal region. The condition is characterized by a hesitant, incomplete, imprecise or even illegible graphomotor output. Letter formation cannot be attributed to sensorimotor, extrapyramidal or cerebellar dysfunction affecting the writing limb. Detailed...
Source: Brain and Language - October 10, 2015 Category: Neurology Authors: Vandenborre D, van Dun K, Engelborghs S, Mariën P Tags: Brain Lang Source Type: research

Hyperbaric oxygen can induce neuroplasticity and improve cognitive functions of patients suffering from anoxic brain damage.
CONCLUSIONS: Although further research is needed, the results demonstrate the beneficial effects of HBO2 on CCI in patients after cardiac arrest, even months to years after the acute event. PMID: 26409406 [PubMed - in process]
Source: Restorative Neurology and Neuroscience - January 25, 2016 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

Changes in Binding of 123 ICLINDE, a High-Affinity Translocator Protein 18 kDa (TSPO) Selective Radioligand in a Rat Model of Traumatic Brain Injury
This study demonstrates the applicability of [123I]CLINDE for detailed regional and quantitative assessment of glial activity in experimental models of TBI.
Source: NeuroMolecular Medicine - March 11, 2016 Category: Neurology Source Type: research

Changes in Binding of 123 ICLINDE, a High-Affinity Translocator Protein 18  kDa (TSPO) Selective Radioligand in a Rat Model of Traumatic Brain Injury
This study demonstrates the applicability of [ 123 I]CLINDE for detailed regional and quantitative assessment of glial activity in experimental models of TBI.
Source: NeuroMolecular Medicine - May 31, 2016 Category: Neurology Source Type: research

Assessment of Hemodynamic Compromise Using Computed Tomography Perfusion in Combination with 123I-IMP Single-Photon Emission Computed Tomography without Acetazolamide Challenge Test
In this study, we investigated whether CT perfusion in combination with resting state 123I-IMP SPECT could be used instead of the acetazolamide challenge test to evaluate hemodynamic compromise in patients with atherosclerotic occlusive disease.
Source: Journal of Stroke and Cerebrovascular Diseases - December 5, 2016 Category: Neurology Authors: Atsumu Hashimoto, Takeshi Mikami, Katsuya Komatsu, Shouhei Noshiro, Tohru Hirano, Masahiko Wanibuchi, Nobuhiro Mikuni Source Type: research

Abnormal neurovascular coupling during status epilepticus migrainosus in Sturge-Weber syndrome
Sturge-Weber syndrome is a rare, sporadic, neurocutaneous disorder classically characterized by a facial nevus in the trigeminal distribution (port wine stain), leptomeningeal angiomatosis, and glaucoma, although intracranial changes can be present without cutaneous involvement.1 Seizures occur in up to 75% of individuals, are often associated with headache, and stroke-like episodes causing prolonged neurologic deficits are also described.1,2
Source: Neurology - January 8, 2017 Category: Neurology Authors: Sethi, M., Kowalczyk, M. A., Dalic, L. J., Archer, J. S., Jackson, G. D. Tags: Migraine, Status epilepticus, Functional neuroimaging, PET in epilepsy, SPECT in epilepsy CLINICAL/SCIENTIFIC NOTES Source Type: research

Cortical Venous Redness Represents Tissue Circulation Status in Patients With Moyamoya Disease Brief Report
Conclusions—Cortical venous redness represented impaired CBF and could be a useful parameter for assessing hemodynamic changes during revascularization surgery.
Source: Stroke - May 22, 2017 Category: Neurology Authors: Toshio Machida, Yoshinori Higuchi, Shigeki Nakano, Satoshi Ishige, Atsushi Fujikawa, Yuichi Akaogi, Junichiro Shimada, Yoichi Yoshida, Sigenori Maru, Junichi Ono Tags: Revascularization, Moyamoya Brief Reports Source Type: research

Accelerated atherosclerosis in ANCA ‐associated vasculitis
ConclusionsOur study adds weight to the presence of increased atherosclerosis in AAV‐patients. The association observed between CIMT and PI‐ICA with small vessel cerebral disease, points the possible association of easy to use carotid US in predicting microvascular brain injury.
Source: Acta Neurologica Scandinavica - June 13, 2017 Category: Neurology Authors: I. Gonz ález‐Suárez, J. J. Ríos‐Blanco, J. Arpa Tags: ORIGINAL ARTICLE Source Type: research