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Safety and Effect of Metoclopramide to Prevent Pneumonia in Patients With Stroke Fed via Nasogastric Tubes Trial Clinical Sciences
Conclusions— This study suggests that metoclopramide may reduce the rate of pneumonia and may improve other clinical outcomes in patients with subacute stroke fed via nasogastric tube. These findings need to be confirmed in larger randomized and blinded trials. Clinical Trial Registration— URL: https://www.clinicaltrialsregister.eu. EudraCT no: 2006-002570-22, URL: http://www.controlled-trials.com/ISRCTN18034911/18034911.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Warusevitane, A., Karunatilake, D., Sim, J., Lally, F., Roffe, C. Tags: Nutrition, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Association between nasogastric tubes, pneumonia, and clinical outcomes in acute stroke patients
Conclusions: Early NGT does not increase PSP incidence, mortality, or poor functional outcomes and can be used safely in acute stroke patients.
Source: Neurology - September 25, 2016 Category: Neurology Authors: Kalra, L., Hodsoll, J., Irshad, S., Smithard, D., Manawadu, D., On behalf of the STROKE-INF Investigators Tags: Outcome research, Medical care, All Cerebrovascular disease/Stroke, Clinical trials Observational study (Cohort, Case control), Class III ARTICLE Source Type: research

Failing a Dysphagia Screening Test after Acute Ischemic Stroke: Baseline Patient Factors and Outcomes (P6.037)
CONCLUSIONS: Patients with ischemic stroke who failed a dysphagia screening test had worse pre-admission function and more severe strokes, and developed much higher rates of complications and death than those who passed. Multivariable analyses are pending to control for stroke severity and determine the strength of these associations.Disclosure: Dr. Joundi has nothing to disclose. Dr. Martino has nothing to disclose. Dr. Saposnik has nothing to disclose. Dr. Fang has nothing to disclose. Dr. Giannakeas has nothing to disclose. Dr. Kapral has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Joundi, R., Martino, R., Saposnik, G., Fang, J., Giannakeas, V., Kapral, M. Tags: In-Hospital Stroke and Stroke Complications Source Type: research

Gastroesophageal Reflux during Enteral Feeding in Stroke Patients: A 24-hour Esophageal pH-monitoring Study
Conclusions: GER is associated with aspiration pneumonia and occurs more often in patients with stroke lesions in the left hemisphere.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2011 Category: Neurology Authors: Yukie Satou, Hiroaki Oguro, Yo Murakami, Keiichi Onoda, Shingo Mitaki, Chizuko Hamada, Ryo Mizuhara, Shuhei Yamaguchi Tags: Original Articles Source Type: research

A Comparative Study of Two Tube Feeding Methods in Patients with Dysphagia After Stroke: A Randomized Controlled Trial
Background: Dysphagia is a common symptom seen in stroke patients, it not only affects patients' nutrition supply, but also causes aspiration pneumonia. To solve the problem of nutritional support for patients with dysphagia after stroke, nasogastric tubes are routinely indwelling to provide nutrition in China. However, this feeding method sometimes causes food reflux, aspiration, pneumonia, and often affects the patients ’ comfort and self-image acceptance. Aim: The aim of this study was to determine whether a new feeding method called intermittent oroesophageal (IOE) tube feeding compared with continuous nasogastric tu...
Source: Journal of Stroke and Cerebrovascular Diseases - January 12, 2020 Category: Neurology Authors: Wei Juan, Huang Zhen, Feng Yan-Ying, Yang Hui-Xian, Zhong Tao, Guo Pei-Fen, Huo Jian-Tian Source Type: research

Oral Health, Oral Microbiota, and Incidence of Stroke-Associated Pneumonia —A Prospective Observational Study
This study involved three investigation timepoints. The baseline investigation (within 24 h of admission) involved collection of demographic, neurological, and immunological data; dental examinations; and microbiological sampling (saliva and subgingival plaque). Further investigation timepoints at 48 or 120 h after baseline included collection of immunological data and microbiological sampling. Microbiological samples were analyzed by culture technique and by 16S rRNA amplicon sequencing. From the 99 patients included in this study, 57 were diagnosed with stroke and 42 were so-called stroke mimics. From 57 stroke patients,...
Source: Frontiers in Neurology - November 6, 2020 Category: Neurology Source Type: research

The impact of aspiration pneumonia and nasogastric feeding on clinical outcomes in stroke patients: a retrospective cohort study
ConclusionHigh prevalence and cost of complications associated with stroke highlights the complexity of providing nursing and allied health care to this patient population. This provides a snap shot of dysphagia related complications experienced by stroke patients.This article is protected by copyright. All rights reserved.
Source: Journal of Clinical Nursing - June 15, 2017 Category: Nursing Authors: Maria Schwarz, Anne Coccetti, Allison Murdoch, Elizabeth Cardell Tags: Original Article Source Type: research

Dysphagia and Factors Associated with Respiratory Infections in the First Week Post Stroke
Conclusion: This study of a large cohort of acute stroke patients supports research indicating aspiration pneumonia is multifactorial in nature. NGT were associated with increased risk of respiratory infections and may contribute to infections by promoting oropharyngeal colonisation. Patients with severely impaired mobility were also at very high risk of respiratory infection.Neuroepidemiology 2014;43:140-144
Source: Neuroepidemiology - November 7, 2014 Category: Epidemiology Source Type: research

E-048 Factors Associated with Early Tracheostomy and Percutaneous Gastrostomy and Their Effects on Hospitalization in Hemorrhagic Stroke Patients
ConclusionsHemorrhagic stroke is a devastating neurovascular event that requires prompt intervention and vigilant management. Our study identified patient risk factors that may suggest candidacy for tracheotomy and PEG. Additionally, we found that timing of PEG may shape a patient’s hospital course. Complication rates related to tracheostomy and PEG in this population were minimal. In conclusion, this retrospective data set supports some benefit to early PEG placement in this population, and justifies the need for further prospective study.DisclosuresM. McCann: None. J. Fraser: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: McCann, M., Fraser, J. Tags: Electronic poster abstracts Source Type: research

Disability and mortality after permanent feeding tube placement in patients with acute stroke (P3.107)
Conclusions:In our large cohort of patients with acute stroke and PEG tubes, nearly 9/10 had severe disability at discharge. From discharge to 1 year, there was no difference in mortality between PEG and NG patient cohorts. These results suggest that PEG tubes serve mainly to prolong survival in patients discharged with severe disability. Our study may help support guideline creation and facilitate discussions with patients and families regarding PEG tube placement after acute stroke.Disclosure: Dr. Joundi has nothing to disclose. Dr. Saposnik has nothing to disclose. Dr. Martino has nothing to disclose. Dr. Fang has nothi...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Joundi, R., Saposnik, G., Martino, R., Fang, J., Giannakeas, V., Porter, J., Kapral, M. Tags: Cerebrovascular Disease and Interventional Neurology Poster Discussion Session Source Type: research

Are Differences in Dysphagia Assessment, Oral Care Provision, or Nasogastric Tube Insertion Associated with Stroke-Associated Pneumonia? A Nationwide Survey Linked to National Stroke Registry Data
Conclusion: Variation exists in dysphagia screening and management, but there was no evidence of an association between clinical practice patterns and incidence of SAP. Further research with larger sample sizes is needed to examine association with SAP.Cerebrovasc Dis
Source: Cerebrovascular Diseases - December 16, 2021 Category: Neurology Source Type: research

Dysphagia Screening Using High-resolution Impedance Manometry in Acute Stroke
Conclusions Our assessment program was safe and effective for assessing swallowing function and for determining the appropriate diet plan.
Source: International Journal of Gerontology - August 9, 2017 Category: Geriatrics Source Type: research

Hochuekkito can Prevent the Colonization of Methicillin-Resistant Staphylococcus aureus in Upper Respiratory Tract of Acute Stroke Patients
Conclusion: Our results indicate that the administration of HET may contribute to the prevention of MRSA colonization and promote rehabilitation in stroke patients.
Source: Frontiers in Pharmacology - June 28, 2021 Category: Drugs & Pharmacology Source Type: research

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