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Total 394 results found since Jan 2013.

Diabetes mellitus and functional limitations among older adults: Evidence from a large, representative Ghanaian aging study
CONCLUSIONS: In this representative study, older adults with DM showed higher odds for FL, and this association was partially explained by physical activity and health variables. Investing in a holistic management approach might be helpful for public health planning efforts to address DM-induced FL in old age.PMID:37677886 | DOI:10.1016/j.jpsychores.2023.111481
Source: Pain Physician - September 7, 2023 Category: Anesthesiology Authors: Razak M Gyasi Julius Odei Mohammed Gazali Hambali Nelson Gyasi-Boadu Bernard Obeng Moses Asori Andr é Hajek Louis Jacob Yvonne Ami Dodzi Adjakloe Jones Opoku-Ware Lee Smith Ai Koyanagi Source Type: research

Signal detection of adverse events associated with gabapentinoid use for chronic pain
CONCLUSIONS: Our study identified expected and unexpected ADE signals in GABA users. Neurological signals likely related to indications for GABA use. Signals for immunity, mental/behavior, and skin disorders were found in the FDA adverse event reporting system database. Unexpected signals of stroke and cancer require further confirmatory analyses to verify.PMID:37640024 | DOI:10.1002/pds.5685
Source: Cancer Control - August 28, 2023 Category: Cancer & Oncology Authors: Yong-Fang Kuo Efstathia Polychronopoulou Mukaila A Raji Source Type: research

End-of-Life Symptoms in Adult Patients With Stroke in the Last Two Years of Life: An Integrative Review
CONCLUSIONS: There is a need for better assessment and management of EOL symptoms in patients with stroke. Established palliative and EOL care guidelines need to be incorporated into clinical practice to ensure access to high-quality care.PMID:37615127 | DOI:10.1177/10499091231197657
Source: The American Journal of Hospice and Palliative Care - August 24, 2023 Category: Palliative Care Authors: Hanna Ramsburg Helene J Moriarty Meredith MacKenzie Greenle Source Type: research

Methemoglobin as a marker of acute anemic stress in cardiac surgery
iScience. 2023 Jul 20;26(8):107429. doi: 10.1016/j.isci.2023.107429. eCollection 2023 Aug 18.ABSTRACTBiological evidence supports plasma methemoglobin as a biomarker for anemia-induced tissue hypoxia. In this translational planned substudy of the multinational randomized controlled transfusion thresholds in cardiac surgery (TRICS-III) trial, which included adults undergoing cardiac surgery requiring cardiopulmonary bypass with a moderate-to-high risk of death, we investigated the relationship between perioperative hemoglobin concentration (Hb) and methemoglobin; and evaluated its association with postoperative outcomes. Th...
Source: Pain Physician - August 14, 2023 Category: Anesthesiology Authors: Nikhil Mistry Gregory M T Hare Nadine Shehata Robert S Kramer Hosam F Fawzy Robert A Baker Paula Carmona Richard Saczkowski Daniela Filipescu Christella S Alphonsus Antoine Rochon Alexander J Gregory Boris Khanykin Jonathan D Leff Eva Mateo Dimos Karangel Source Type: research

How do patients with Type 2 Diabetes Mellitus value the importance of outcomes? An overview of reviews
CONCLUSION: We provide standardised, reliable utility values (or associated disutilities) for T2DM, acute, microvascular and macrovascular complications, related comorbidities and treatments that may support judgements when making clinical recommendations, designing decision support tools, and developing interventions and economic analysis.PMID:37516195 | DOI:10.1016/j.jval.2023.07.003
Source: Cancer Control - July 29, 2023 Category: Cancer & Oncology Authors: Ena Nino-de-Guzman Javier Bracchiglione Adrian Vasquez-Mejia Gimon de Graaf Claudio Rocha Calderon Pablo Alonso-Coello Source Type: research

Pediatric Moyamoya Revascularization Perioperative Care: A Modified Delphi Study
ConclusionsIn the absence of data supporting specific care practices before and after indirect revascularization surgery in children with moyamoya, this Delphi process defined areas of consensus among neurosurgeons, neurologists, and intensivists with moyamoya expertise. Research priorities identified include determining the role of continuous electroencephalography in postoperative moyamoya care, optimal perioperative blood pressure and hemoglobin targets, and the role of supplemental oxygen for treatment of suspected postoperative ischemia.
Source: Neurocritical Care - July 20, 2023 Category: Neurology Source Type: research

Early versus late injections of Botulinumtoxin type A in post-stroke spastic movement disorder: A literature review
Toxicon. 2023 May 3:107150. doi: 10.1016/j.toxicon.2023.107150. Online ahead of print.ABSTRACTPost-stroke spastic movement disorder (PS-SMD) is one of the main causes of severe disability in the chronic phase after stroke. The prevalence of SMD rises up with time after stroke to more than 28% in the chronic phase, and its secondary complications such as contracture, abnormal postures and/or movement patterns, spasticity-associated pain, also increases with time after stroke when physical and medical management of PS-SMD had been delayed in the early stroke phase. It has been published by several controlled studies that the...
Source: Toxicon - May 5, 2023 Category: Toxicology Authors: J örg Wissel Songjin Ri Anatol Kivi Source Type: research

Measuring Pain in Aphasia: Validity and Reliability of the PACSLAC-D
Post-stroke pain in patients with an inability to communicate is not systematically assessed and therefore not sufficiently treated. This stresses the need to study pain assessment instruments that do not require good communication skills.
Source: Pain Management Nursing - April 24, 2023 Category: Nursing Authors: Neeltje J. de Vries, Jenny T. van der Steen, Wilco P. Achterberg, Hanneke J.A. Smaling Tags: Original Article Source Type: research

Top 20 Research Studies of 2022 for Primary Care Physicians
This article summarizes the top 20 research studies of 2022 identified as POEMs (patient-oriented evidence that matters), excluding COVID-19. Statins for primary prevention of cardiovascular disease produce only a small absolute reduction in a person's likelihood of dying (0.6%), having a myocardial infarction (0.7%), or having a stroke (0.3%) over three to six years. Supplemental vitamin D does not reduce the risk of a fragility fracture, even in people with low baseline vitamin D levels or a previous fracture. Selective serotonin reuptake inhibitors are preferred medical therapy for panic disorder, and patients who disco...
Source: American Family Physician - April 13, 2023 Category: Primary Care Authors: Roland Grad Mark H Ebell Source Type: research