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7 ways neurostimulation could make our lives better
  [Image from dierk schaefer on Flickr]Neurostimulation is being used for a lot of different things that go beyond motor disorders and diseases. Neurostimulation is used to stimulate certain parts of the brain’s nervous system. It can be invasive with implants or it can be non-invasive with electrode-filled caps and ear clips. The neurostimulation market was worth an estimated $1.9 billion in 2016 and expected to double to almost $4 billion by 2025, according to a ReportBuyer analysis. The continuously growing range of applications and updates in the technology are contributing to the fast growth. From devices to tr...
Source: Mass Device - July 27, 2017 Category: Medical Devices Authors: Danielle Kirsh Tags: Neurological Neuromodulation/Neurostimulation Pain Management Research & Development Cleveland Clinic Hartford Healthcare Massachusetts Institute of Technology Medtronic Northwestern University University of Washington Source Type: news

Randomized clinical trial of deep brain stimulation for post ‐stroke pain
This article is protected by copyright. All rights reserved.
Source: Annals of Neurology - April 5, 2017 Category: Neurology Authors: Scott F. Lempka, Donald A. Malone, Bo Hu, Kenneth B. Baker, Alexandria Wyant, John Ozinga, Ela B. Plow, Mayur Pandya, Cynthia S. Kubu, Paul J. Ford, Andre G. Machado Tags: Research Article Source Type: research

Hypercoagulability and Migraine
BackgroundA growing body of literature suggests that migraineurs, particularly those with aura, have an increased risk for ischemic stroke, but not via enhanced atherosclerosis. The theory that micro‐emboli induced ischemia provokes cortical spreading depression (ie, symptomatic aura) in migraineurs but transient ischemic attacks in others highlights a potential role for hypercoagulability as a link between migraine (with aura) and stroke. AimOur objective is to summarize the literature evaluating the association of migraine with various acquired or inheritable thrombophilic states, including those related to elevated es...
Source: Headache: The Journal of Head and Face Pain - February 8, 2017 Category: Neurology Authors: Gretchen E. Tietjen, Stuart A. Collins Tags: Headache Currents Source Type: research

Ketamine Therapy for Treatment-resistant Depression in a Patient with Multiple Sclerosis: A Case Report
Conclusion—Ketamine may be an alternative treatment for resistant depression and may have a special use in patients with multiple sclerosis. Introduction Depression is a frequent finding in patients with multiple sclerosis (MS), with the lifetime prevalence rates for major depressive disorder (MDD) ranging from 36 to 54 percent, more than twice of that in the general population.[1] Even with advances in pharmacological options for treating depression, an estimated 33 to 66 percent of patients with MDD in the general population do not respond to the first antidepressant, and a reported 15 to 33 percent of patients do not ...
Source: Innovations in Clinical Neuroscience - February 1, 2017 Category: Neuroscience Authors: ICN Online Editor Tags: Case Report Current Issue Depression Multiple Sclerosis Neurology Psychiatry Psychopharmacology Electroconvulsive therapy Ketamine major depressive disorder treatment-resistant depression Source Type: research

Dementia and co ‐occurring chronic conditions: a systematic literature review to identify what is known and where are the gaps in the evidence?
ConclusionsThis review summarizes that living with significant cognitive impairment or dementia negatively impacts mortality, institutionalization, and functional outcomes for people living with multiple chronic conditions. Our findings suggest that chronic‐disease management interventions will need to address co‐occurring cognitive impairment. Copyright © 2017 John Wiley & Sons, Ltd.
Source: International Journal of Geriatric Psychiatry - January 31, 2017 Category: Geriatrics Authors: Mark B. Snowden, Lesley E. Steinman, Lucinda L. Bryant, Monique M. Cherrier, Kurt J. Greenlund, Katherine H. Leith, Cari Levy, Rebecca G. Logsdon, Catherine Copeland, Mia Vogel, Lynda A. Anderson, David C. Atkins, Janice F. Bell, Annette L. Fitzpatrick Tags: Review Article Source Type: research

Editor ’ s Message: September –October 2016 Issue Highlights
Dear Colleagues: Welcome to the September-October 2016 issue of Innovations in Clinical Neuroscience (ICNS). As the official journal of the CNS Summit, the International Society for CNS Drug Development (ISCDD), and the International Society for CNS Clinical Trials and Methodology (ISCTM), an important part of our editorial mission is to accelerate and enhance of the development of cheaper, more effective treatments for our patients through technology, collaboration, and innovation—not just in neuroscience but in all disciplines of medicine and among all involved entities, including clinicians, researchers, and members o...
Source: Innovations in Clinical Neuroscience - October 9, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Current Issue Drug Development Editor's Message: Issue Highlights Neurology Psychiatry Trial Methodology Amir H. Kalali CNS Summit Innovations in Clinical Neuroscience ISCDD ISCTM Source Type: research

Usefulness and effectiveness of herbal medicines in stroke: Narrative review
ABSTRACT Stroke causes various disabilities, reducing the quality of life and motivation for life. It is also one of the major causes of death in the aging population. Therefore, prevention and treatment are crucial. In conventional medicine, thrombolysis and various surgical techniques have been developed and used to treat stroke, but, despite the advancements and benefits, many patients still experience various disabilities. In East Asian countries, herbal prescriptions have been widely used for the treatment and prevention of stroke. Recently, the efficacy of herbal complexes as an adjunct to conventional treatment has ...
Source: Traditional and Kampo Medicine - September 30, 2016 Category: Complementary Medicine Authors: Ki ‐Ho Cho, Seungwon Kwon Tags: REVIEW Source Type: research

Hemiplegic Shoulder Pain Reduces Quality of Life After Acute Stroke: A Prospective Population-Based Study
Conclusion: Hemiplegic shoulder pain reduces health-related quality of life at 12 months. More effort should be directed towards screening and management of this frequent complication of stroke.
Source: American Journal of Physical Medicine and Rehabilitation - September 20, 2016 Category: Rehabilitation Tags: Original Research Articles Source Type: research

Patterns and consequences of multimorbidity in the general population: There is no chronic disease management without rheumatic disease management
Conclusion: Our study emphasizes RMDs as a major presence in multimorbidity in the general population. All multimorbidity patterns were associated with a wide set of adverse health outcomes. Management strategies for the patient with chronic cardiometabolic, respiratory or depressive conditions should also target RMDs. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - August 1, 2016 Category: Rheumatology Authors: Daniela Sim ões, Fábio A. Araújo, Milton Severo, Teresa Monjardino, Ivo Cruz, Loreto Carmona, Raquel Lucas Tags: Original Article Source Type: research

Skew Deviation: Case Report and Review of the Literature.
CONCLUSION: Skew deviation, a not uncommon clinical condition, should be promptly recognized when binocular vertical diplopia cannot be interpreted by trochlearis and oculomotor nerve lesion, myasthenia gravis, or orbital pathology. Maddox rod, cover test, Parks-Bielschowsky three-step, and other tests should help to establish the diagnosis. The prognosis depends on etiology, but it is commonly favorable; the majority of patients recover spontaneously after less than a year. More invasive management options should be discussed thereafter. PMID: 27471949 [PubMed - as supplied by publisher]
Source: Seminars in Ophthalmology - July 31, 2016 Category: Opthalmology Tags: Semin Ophthalmol Source Type: research

MassDevice.com +5 | The top 5 medtech stories for July 8, 2016
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. Nexstim wins CE Mark for brain therapy treatment for chronic neuropathic pain Brain therapy system developer Nexstim said late last month it won expanded CE Mark approval in the European Union for its Navigated Brain Therapy sy...
Source: Mass Device - July 8, 2016 Category: Medical Equipment Authors: MassDevice Tags: News Well Plus 5 Source Type: news

Nexstim wins CE Mark for brain therapy treatment for chronic neuropathic pain
Brain therapy system developer Nexstim said late last month it won expanded CE Mark approval in the European Union for its Navigated Brain Therapy system, now cleared for the relief of chronic neuropathic pain. The NBT system uses navigated transcranial magnetic stimulation to treat exact areas in the brain using a 3D image rendered from a patients MRI scan, and has existing clearances for treating major depression and for use in stroke rehabilitation therapy. “Chronic neuropathic pain is a debilitating condition worldwide with few effective therapeutic options. With our NBT technology we have the potential to make a...
Source: Mass Device - July 8, 2016 Category: Medical Equipment Authors: Fink Densford Tags: Neurological Neuromodulation/Neurostimulation Pain Management Regulatory/Compliance Nexstim Source Type: news

Fatigue in rheumatoid arthritis 'may need to be treated separately'
This study highlights the need for better treatments for fatigue, which can be used alongside existing medication. We need to ensure fatigue has recognition from medical professionals so people can get the care they require."Along with pain, fatigue is one of the things that people with arthritis tell us has the biggest impact on their lives, which is why Arthritis Research UK is funding research into coping with the effects of fatigue on a day-to-day basis."
Source: Arthritis Research UK - June 23, 2016 Category: Rheumatology Source Type: news

Decrease the Symptoms of Sleep Apnea
by Phil Hardesty New research is showing that exercise not only helps the quality of our sleep, but it can improve conditions such as obstructive sleep apnea, or OSA. What is OSA? Obstructive sleep apnea is a condition where a person's breathing frequently pauses during sleep. One of the most noticeable sign of OSA is snoring. Other signs and symptoms of OSA are: Excessive daytime fatigue and sleepiness Observed episodes of breathing cessation during sleep Abrupt awakenings accompanied by shortness of breath Awakening with a dry mouth or sore throat Awakening with chest pain Sudden waking with gasping for breath Mornin...
Source: Healthy Living - The Huffington Post - June 6, 2016 Category: Consumer Health News Source Type: news

Musculoskeletal and central pain at 1 year post‐stroke: associated factors and impact on quality of life
ConclusionsPain is common 12 months post‐stroke. The factors associated with CPSP and MSP differ, but are both closely associated with fatigue rather than depression. QOL is the poorest in patients with combined pain. Management of pain and fatigue may be important for improving the QOL in stroke patients.
Source: Acta Neurologica Scandinavica - June 6, 2016 Category: Neurology Authors: S. Choi‐Kwon, S. H. Choi, M. Suh, S. Choi, K.‐H. Cho, H.‐W. Nah, H. Song, J. S. Kim Tags: Original Article Source Type: research