Filtered By:
Specialty: Drugs & Pharmacology
This page shows you your search results in order of date. This is page number 18.
Order by Relevance | Date
Total 5519 results found since Jan 2013.
Effectiveness and safety of Dabigatran 110 mg versus 150 mg for Stroke Prevention in Patients with Atrial Fibrillation at High Bleeding Risk
Clin Ther. 2023 Jun 26:S0149-2918(23)00192-3. doi: 10.1016/j.clinthera.2023.05.007. Online ahead of print.ABSTRACTPURPOSE: The effectiveness and tolerability of a reduced dose (110 mg) of dabigatran versus the standard dose (150 mg) were evaluated in subgroups of patients with atrial fibrillation (AF) at high bleeding risk.METHODS: Eligible patients were adults with AF and a creatinine clearance rate ≥30 mL/min who were initiated on treatment with dabigatran (index) between 2016 and 2018. High-bleeding-risk subgroups were identified: (1) age ≥80 years; (2) moderate renal impairment (creatinine clearance rate 30-<50 ...
Source: Clinical Therapeutics - June 28, 2023 Category: Drugs & Pharmacology Authors: Jaejin An T Craig Cheetham Tiffany Luong Daniel T Lang Ming-Sum Lee Kristi Reynolds Source Type: research
Predicting treatment effects of a new-to-market drug in clinical practice based on phase III randomized trial results
Clin Pharmacol Ther. 2023 Jun 26. doi: 10.1002/cpt.2983. Online ahead of print.ABSTRACTTrial results may not be generalizable to target populations treated in clinical practice with different distributions of baseline characteristics that modify the treatment effect. We used outcome models developed with trial data to predict treatment effects in Medicare populations. We used data from the Randomized Evaluation of Long-Term Anticoagulation Therapy trial (RE-LY), which investigated the effect of dabigatran vs. warfarin on stroke or systemic embolism (stroke/SE) among patients with atrial fibrillation. We developed outcome m...
Source: Clinical Pharmacology and Therapeutics - June 27, 2023 Category: Drugs & Pharmacology Authors: HoJin Shin Shirley V Wang Dae Hyun Kim Ethan Alt Mufaddal Mahesri Lily G Bessette Sebastian Schneeweiss Mehdi Najafzadeh Source Type: research
Current Landscape of Therapeutics for the Management of Hypertension - A Review
Curr Drug Deliv. 2023 Jun 23. doi: 10.2174/1567201820666230623121433. Online ahead of print.ABSTRACTHypertension is a critical health problem. It is also the primary cause of coronary heart disease, stroke, and renal vascular disease. The use of herbal drugs in the management of any disease is increasing. They are considered the best immune booster to fight against several types of diseases. To date, the demand for herbal drugs has been increasing because of their excellent properties. This review highlights antihypertensive drugs, polyphenols, and synbiotics for managing hypertension. Evidence is mounting in favour of mor...
Source: Current Drug Delivery - June 26, 2023 Category: Drugs & Pharmacology Authors: Neda Fatima Sumel Ashique Aakash Upadhyay Shubneesh Kumar Himanshu Kumar Nitish Kumar Prashant Kumar Source Type: research
Prescriptive behavior of non-vitamin K oral anticoagulants in patients affected by atrial fibrillation in general practice
Biomed Pharmacother. 2023 Jun 21;165:115020. doi: 10.1016/j.biopha.2023.115020. Online ahead of print.ABSTRACTAtrial fibrillation (AF) is the most common cardiac arrhythmia worldwide and in recent years the pharmacological approach has been strongly implemented; in Italy, the prescription of the non-vitamin K oral anticoagulants (NOAC) was also extended to General Practitioners (GPs) since 2020. The aim of the present study was to investigate the GPs prescribing behaviour of NOACs. An observational study was performed by using the computerized medical record of 14 GPs in Sicily: patients affected by AF were selected and st...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - June 23, 2023 Category: Drugs & Pharmacology Authors: M Rottura S F A Drago A Molonia N Irrera S Marino R Scoglio L Orlando M Gigliotti De Fazio F Squadrito V Arcoraci E Imbalzano on the behalf of Audit & Research Messina Primary Care Group Source Type: research
Clinical Efficacy of the Huo Xue Hua Yu Method Combined with Aspirin in the Treatment of Acute Cerebral Infarction: A systematic evaluation and Meta-Analysis
CONCLUSION: The combination of the Huo Xue Hua Yu method and aspirin represents a beneficial adjunctive therapy for ACI.PMID:37349997 | DOI:10.2174/1381612829666230622110753
Source: Current Pharmaceutical Design - June 23, 2023 Category: Drugs & Pharmacology Authors: Chu Chen Fang Ma Xinli Wen Xing Liu Qing Tang Yilun Wu Source Type: research
Prescriptive behavior of non-vitamin K oral anticoagulants in patients affected by atrial fibrillation in general practice
Biomed Pharmacother. 2023 Jun 21;165:115020. doi: 10.1016/j.biopha.2023.115020. Online ahead of print.ABSTRACTAtrial fibrillation (AF) is the most common cardiac arrhythmia worldwide and in recent years the pharmacological approach has been strongly implemented; in Italy, the prescription of the non-vitamin K oral anticoagulants (NOAC) was also extended to General Practitioners (GPs) since 2020. The aim of the present study was to investigate the GPs prescribing behaviour of NOACs. An observational study was performed by using the computerized medical record of 14 GPs in Sicily: patients affected by AF were selected and st...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - June 23, 2023 Category: Drugs & Pharmacology Authors: M Rottura S F A Drago A Molonia N Irrera S Marino R Scoglio L Orlando M Gigliotti De Fazio F Squadrito V Arcoraci E Imbalzano on the behalf of Audit & Research Messina Primary Care Group Source Type: research
Clinical Efficacy of the Huo Xue Hua Yu Method Combined with Aspirin in the Treatment of Acute Cerebral Infarction: A systematic evaluation and Meta-Analysis
CONCLUSION: The combination of the Huo Xue Hua Yu method and aspirin represents a beneficial adjunctive therapy for ACI.PMID:37349997 | DOI:10.2174/1381612829666230622110753
Source: Current Pharmaceutical Design - June 23, 2023 Category: Drugs & Pharmacology Authors: Chu Chen Fang Ma Xinli Wen Xing Liu Qing Tang Yilun Wu Source Type: research
