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Condition: Epilepsy

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Total 2623 results found since Jan 2013.

Hospital Revisits for Post-Ischemic Stroke Epilepsy after Acute Stroke Interventions
Improvements in acute stroke care, namely the use of intravenous alteplase (IV-tPA) and mechanical thrombectomy (MT), have led to a considerable increase in the proportion of patients who survive a first-time ischemic stroke.1 Despite demonstrated benefits of acute stroke interventions, their impact on long term complications is not yet clear. One such complication is post-ischemic stroke epilepsy (PISE). PISE is estimated to occur in 2 –6% of stroke survivors,2–4 and is associated with poor-quality of life and high mortality in young patients.
Source: Journal of Stroke and Cerebrovascular Diseases - October 21, 2021 Category: Neurology Authors: Lindsey R. Kuohn, Alison L. Herman, Alexandria L. Soto, Stacy C. Brown, Emily J. Gilmore, Lawrence J. Hirsch, Charles C. Matouk, Kevin N. Sheth, Jennifer A. Kim Source Type: research

Is the outpatient management of acute minor stroke feasible and safe?
Paul et al1 have assessed the clinical outcomes, early hospital admission rates and hospital care costs in clinic referred and hospital referred minor stroke patients in a prospective population based study. They did not find significant differences in the 30 day admission rate in clinic patients compared with the 30 day readmission rate after discharge in hospital treated patients (16/237 vs 9/150). The 30 day recurrent stroke risk in patients with minor ischaemic stroke was also similar in those discharged from clinic compared with hospital patients (3.8% vs 5.3%; p=0.61). The recurrent stroke risk remained similar in pa...
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 15, 2013 Category: Neurosurgery Authors: Csiba, L. Tags: Epilepsy and seizures, Stroke, Hypertension Editorial commentaries Source Type: research

Incidence and Associations of Poststroke Epilepsy: The Prospective South London Stroke Register Clinical Sciences
Conclusions— PSE is common, with risk continuing to increase outside the acute phase. Young age, cortical location, larger lesions, and hemorrhagic lesions are independent predictors.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Graham, N. S. N., Crichton, S., Koutroumanidis, M., Wolfe, C. D. A., Rudd, A. G. Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction Clinical Sciences Source Type: research

Seizures after decompressive hemicraniectomy for ischaemic stroke
Conclusions In this case series, patients were at high risk of developing seizures after malignant MCA stroke with DHC, especially after cranioplasty. Assuming these findings are replicated, means should be sought to reduce the occurrence of this complication.
Source: Journal of Neurology, Neurosurgery and Psychiatry - June 10, 2014 Category: Neurosurgery Authors: Creutzfeldt, C. J., Tirschwell, D. L., Kim, L. J., Schubert, G. B., Longstreth, W. T., Becker, K. J. Tags: Epilepsy and seizures, Stroke Cerebrovascular disease Source Type: research

Predictive factors for the development of epilepsy after ischemic stroke
In Argentina, each year approximately 50,000 people suffer an ischemic or hemorrhagic stroke1 and 340,000 people over 40 years old live with a history of stroke.2 The advent of therapies such as thrombolysis and thrombectomy achieved a substantial reduction in morbidity and mortality.3 In addition, stroke survivors have an increased risk of spontaneous seizures and the number of people who have survived a stroke but have motor, visual or cognitive sequelae is high.4 Post-stroke epilepsy (PSE) is a condition where seizures occur more than 7 days after stroke, with a high risk of recurrent unprovoked seizures over the subsequent 10-years.
Source: Journal of Stroke and Cerebrovascular Diseases - November 4, 2022 Category: Neurology Authors: Mat ías Alet, Fernando Márquez, Abril Marone, Maximiliano Darakdjian, Federico Sosa, Lucas Bonamico, Sebastián F. Ameriso Source Type: research

Haemorrhagic stroke in term and late preterm neonates
Conclusions In our cohort with acute HS, most presented with seizures, apnoea and/or poor feeding. Fetal distress and CHD were common. Nearly two-thirds had intraparenchymal with intraventricular haemorrhage. Over half were due to haemorrhagic transformation of infarction. Short-term neurologic deficits were present in 47% of survivors.
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - December 13, 2013 Category: Perinatology & Neonatology Authors: Bruno, C. J., Beslow, L. A., Witmer, C. M., Vossough, A., Jordan, L. C., Zelonis, S., Licht, D. J., Ichord, R. N., Smith, S. E. Tags: Epidemiologic studies, Congenital heart disease, Drugs: cardiovascular system, Drugs: CNS (not psychiatric), Epilepsy and seizures, Hydrocephalus, Stroke, Pregnancy, Child health Original articles Source Type: research

Stroke and nonstroke brain attacks in children
Conclusions: Brain attack etiologies differ from adults, with stroke being the fourth most common diagnosis. These findings will inform development of ED clinical pathways for pediatric brain attacks.
Source: Neurology - April 21, 2014 Category: Neurology Authors: Mackay, M. T., Chua, Z. K., Lee, M., Yock-Corrales, A., Churilov, L., Monagle, P., Donnan, G. A., Babl, F. E. Tags: Childhood stroke, All Cerebrovascular disease/Stroke, All Pediatric, Prevalence studies ARTICLE Source Type: research

Neuroimaging Markers of Cognitive Outcome in Children with Perinatal Stroke (I2.002)
Conclusions: As seen in other studies, prognosis of cognitive outcome is difficult and there was no correlation between site of lesion and areas of intellectual deficit. However, there was some indication that loss of more cortical volume, or involvement of the DLPF cortex may be risk factors for intellectual impairment in childhood.Disclosure: Dr. Murias has nothing to disclose. Dr. Kirton has nothing to disclose. Dr. Tariq has nothing to disclose. Dr. Moir has nothing to disclose. Dr. Iaria has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Murias, K., Kirton, A., Tariq, S., Moir, A., Iaria, G. Tags: Stroke in the Elderly and Young: Challenges for the Next Decade Data Blitz Presentations Source Type: research

Neuroimaging Markers of Cognitive Outcome in Children with Perinatal Stroke (P3.256)
Conclusions: As seen in other studies, prognosis of cognitive outcome is difficult and there was no correlation between site of lesion and areas of intellectual deficit. However, there was some indication that loss of more cortical volume, or involvement of the DLPF cortex may be risk factors for intellectual impairment in childhood.Disclosure: Dr. Murias has nothing to disclose. Dr. Kirton has nothing to disclose. Dr. Tariq has nothing to disclose. Dr. Moir has nothing to disclose. Dr. Iaria has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Murias, K., Kirton, A., Tariq, S., Moir, A., Iaria, G. Tags: Child Neurology and Developmental Neurology: Epilepsy, Hypoxia, and Stroke Source Type: research

Risk assessment of mechanic thrombectomy on post-stroke seizures: a systematical review and meta-analysis
Acute ischemic stroke is a leading cause of disability, with over a third of survivors developing new post-stroke disabilities around the world.1 Many post-stroke patients have a significant higher risk of developing post-stroke seizures of which the incidence has also been increasing over the past decades.2 Cerebrovascular disease is the leading cause of seizures in adults over 60-year-old, which has been shown to account for nearly 50% of newly diagnosed epilepsy in this age group.3
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2023 Category: Neurology Authors: Wen Jiang, Xiaoyan Zhu, Chunyan Lei, Guoliang Jiang, Linming Zhang, Song Mei, Lianmei Zhong Source Type: research

Survivors Of Stroke In Infancy Prone To Seizures, Epilepsy
About one-third of American infants and children who suffer bleeding into brain tissue, may later have seizures and as many as 13 percent will develop epilepsy within two years, according to new research reported at the American Stroke Association's International Stroke Conference 2013. Bleeding into brain tissue is a type of stroke called intracerebral hemorrhage (ICH). Each year, an estimated 6.4 newborns and children per every 100,000 in the United States suffer strokes. About half of the strokes are hemorrhagic, typically caused by rupturing of weakened or malformed blood vessels...
Source: Health News from Medical News Today - February 11, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Diagnosis and acute management of perinatal arterial ischemic stroke
Perinatal arterial ischemic stroke (PAIS) can be an unrecognized cause of short- and long-term neurologic disability. Focal clonic seizure in the newborn period is the most common clinical presentation of PAIS. MRI is optimal in diagnosing PAIS; negative cranial ultrasound or CT does not rule out PAIS. Given the low rate of recurrence in combination with risk factors thought to be isolated to the maternal-fetal unit, anticoagulation or antiplatelet treatment is usually not recommended. The majority of newborns with PAIS do not go on to develop epilepsy, although further research is warranted in this area. Long-term morbidi...
Source: Nature Clinical Practice - October 13, 2014 Category: Neurology Authors: Armstrong-Wells, J., Ferriero, D. M. Tags: Childhood stroke, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke, Neonatal Clinical and Ethical Challenges Source Type: research

Anti-Seizure Medication Management Associated with Electroencephalography in Patients with Acute Ischemic Stroke Suspected of Seizure (P6.039)
CONCLUSIONS: In our sample population, the absence of epileptiform discharges on EEG did not routinely lead to a discontinuation of anti-seizure medications. More than one third of patients who had EEG without epileptiform discharges were started on an anti-seizure medication and more than half of these patients were continued on anti-seizure medication(s) through discharge, raising concern for unnecessary exposure to medications with negative implications for neurological recovery.Disclosure: Dr. Rao has nothing to disclose. Dr. Monlezun, Jr has nothing to disclose. Dr. Kimbrough has nothing to disclose. Dr. Samai has not...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Rao, R., Monlezun, Jr, D., Kimbrough, T., Samai, A., Burkett, B., El Khoury, R., Martin-Schild, S. Tags: In-Hospital Stroke and Stroke Complications Source Type: research

Risk Factors of Post-Stroke Epilepsy in Children; Experience from a Tertiary Center and a Brief Review of the Literature
Arterial ischemic stroke (AII) is a significant cause of acute seizures, and survivors frequently develop post-stroke epilepsy (PSE).1 The frequency of PSE has been widely studied in adults. Post-stroke seizures have been reported in 5 –20% of elderly individuals, whereas the development of epilepsy is rare and ranges from 2% to 15%.2–4 Few studies have investigated risk factors for PSE in children. Due to variations in study population characteristics, sample size, and age range, PSE frequencies vary in children.
Source: Journal of Stroke and Cerebrovascular Diseases - November 13, 2020 Category: Neurology Authors: İpek Polat, Uluç Yiş, Müge Ayanoğlu, Derya Okur, Pınar Edem, Cem Paketçi, Erhan Bayram, Semra Hız Kurul Source Type: research

Acute seizures in the acute ischemic stroke setting: A step forward in their description
Although the incidence of acute seizures after ischemic strokes is small, about 1.2%–4.2%,1,2 they still represent a substantial clinical challenge. There are no clear management guidelines, and the effect on stroke outcome is a matter of debate.3 Moreover, experiencing a seizure at the stroke onset may represent a relative contraindication for thrombolysis.4 Despite all of these clinical pitfalls and multiple published studies, there remains a lack of knowledge regarding acute seizures after acute ischemic strokes. In this issue of Neurology®, Huang et al.5 add information to this field.
Source: Neurology - March 3, 2014 Category: Neurology Authors: Alvarez, V. Tags: All Cerebrovascular disease/Stroke, All Practice Management, All Epilepsy/Seizures EDITORIALS Source Type: research