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Total 7365 results found since Jan 2013.

Global and national burden of atherosclerosis from 1990 to 2019: trend analysis based on the Global Burden of Disease Study 2019
CONCLUSIONS: From 1990 to 2019, there was an overall increasing trend in the global incidence of all three clinical manifestations of atherosclerosis. Between 1990 and 2019, both the mortality rate and DALYs for IHD and ischemic stroke declined across all age groups. Overall, the burden of atherosclerosis-related diseases has not significantly decreased and even shows signs of trending upward. These findings strongly suggest that despite some progress made, efforts to control atherosclerosis diseases globally need to be intensified.PMID:37677929 | DOI:10.1097/CM9.0000000000002839
Source: Chinese Medical Journal - September 7, 2023 Category: General Medicine Authors: Weihua Chen Zeya Li Yu Zhao Yitian Chen Rongchong Huang Source Type: research

Disparities in ethnicity and metabolic disease burden in referrals to nephrology
CONCLUSION: A disproportionately large number of Malay patients are referred for kidney disease. These patients have higher metabolic disease burden, tend to miss appointments and are referred at lower eGFR. Reasons underpinning these associations should be identified to facilitate efforts for targeting this at-risk population, ensuring kidney health for all.PMID:37675684 | DOI:10.4103/singaporemedj.SMJ-2022-193
Source: Singapore Medical Journal - September 7, 2023 Category: General Medicine Authors: Yan Ting Chua Cheang Han Leo Horng Ruey Chua Weng Kin Wong Gek Cher Chan Anantharaman Vathsala Ye Lu Mavis Gan Boon Wee Teo Source Type: research

Statins may Decrease Aneurysm wall Enhancement of Unruptured Fusiform Intracranial Aneurysms: A high-resolution 3T MRI Study
AbstractInflammation plays an integral role in the formation, growth, and progression to rupture of unruptured intracranial aneurysms. Aneurysm wall enhancement (AWE) in high-resolution magnetic resonance imaging (HR-MRI) has emerged as a surrogate biomarker of vessel wall inflammation and unruptured intracranial aneurysm instability. We investigated the correlation between anti-inflammatory drug use and three-dimensional AWE of fusiform intracranial aneurysms (FIAs). We retrospectively analyzed consecutive patients with FIAs in our database who underwent 3T HR-MRI at three Chinese centers. FIAs were classified as fusiform...
Source: Translational Stroke Research - September 7, 2023 Category: Neurology Source Type: research

Total saponins from Trillium tschonoskii Maxim promote neurological recovery in model rats with post-stroke cognitive impairment
Total saponins from Trillium tschonoskii Maxim (TSTT), a bioactive component of local natural herbs in the Enshi area, China, have been demonstrated to have functions of restoring cognitive capacity and promoting axonal regeneration post-stroke, but the mechanism of this process remains unclear. The hippocampus is a critical tissue for controlling learning and memory capacity, and the sonic hedgehog (Shh) signaling pathway plays a major role in the patterning and synaptic plasticity of hippocampal neural circuits. Therefore, we aimed to investigate whether TSTT could restore learning and cognitive functions by modulating t...
Source: Frontiers in Pharmacology - September 7, 2023 Category: Drugs & Pharmacology Source Type: research

Chemical composition, pharmacology and pharmacokinetic studies of GuHong injection in the treatment of ischemic stroke
This article represents a comprehensive and systematic review of existing studies on GuHong injection, including chemical composition, pharmacological mechanism, and pharmacokinetics, which provides reference significance for the clinical treatment of ischemic stroke with GuHong, as well as provides guidance for further study.
Source: Frontiers in Pharmacology - September 7, 2023 Category: Drugs & Pharmacology Source Type: research

Potentially Inappropriate Medication Use Among Older Patients with Diabetes in a Chinese Community
Conclusions Given the higher rate of PIM use among older adults with diabetes, strategies and interventions targeting this population are needed to minimize PIM use. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text
Source: Experimental and Clinical Endocrinology and Diabetes - September 6, 2023 Category: Endocrinology Authors: Zhao, Xingxing Li, Lei Guo, Xiujun Wang, Jianqiang Yan, Yingying Le, Yunyi Tags: Article Source Type: research

Association of baseline fasting plasma glucose with 1-year mortality in non-diabetic patients with acute cerebral infarction: a multicentre observational cohort study
Conclusion In non-diabetic patients with ACI, elevated baseline FPG is an independent risk factor for 1-year all-cause mortality, and the two are positively and non-linearly associated. These results suggest that high FPG should be seen as a concern in non-diabetic patients with ACI.
Source: BMJ Open - September 6, 2023 Category: General Medicine Authors: Zhang, D., Liu, Z., Liu, P., Zhang, H., Guo, W., Lu, Q., Huang, C., Wang, J., Chang, Q., Zhang, M., Huo, Y., Wang, Y., Lin, X., Wang, F., Wu, S. Tags: Open access, Neurology Source Type: research

Effect of Qigong exercise on non ‐motor function and life quality in stroke patients: A systematic review and meta‐analysis
ConclusionsPooled results suggested that Qigong had beneficial effects on ADL, neurological function, and life quality in stroke patients, which may provide an option for their rehabilitation.
Source: Brain and Behavior - September 5, 2023 Category: Neurology Authors: Yi Lan, Qiqi You, Qingqing Jiang, Xiaoxiang Peng, Shiyi Cao, Jian Sun Tags: REVIEW Source Type: research

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