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Total 6068 results found since Jan 2013.

Effectiveness and safety of Angong Niuhuang pill in treatment of acute stroke: a systematic review and Meta-analysis
CONCLUSIONS: Existing clinical research evidence shows that ANP has good efficacy and safety in the treatment of acute stroke, which can provide a basis for the treatment of integrated Traditional Chinese and Western Medicine. However, the quality of included research methodology needs to be improved, and the above conclusions need to be verified by more high-quality studies.PMID:37454249 | PMC:PMC10320440 | DOI:10.19852/j.cnki.jtcm.20230526.002
Source: Journal of Traditional Chinese Medicine - July 16, 2023 Category: Complementary Medicine Authors: Meng Xiangran Cao Xue Sun Minglin A I Yanke H E Liyun Liu Jia Source Type: research

Dengyinnaotong attenuates atherosclerotic lesions, gut dysbiosis and intestinal epithelial barrier impairment in the high fat diet-fed ApoE < sup > -/- < /sup > mice
CONCLUSIONS: Our work provides novel preclinical evidence that underpins the multifaceted effects of DYNT in the control of atherosclerosis.PMID:37453620 | DOI:10.1016/j.jep.2023.116916
Source: Atherosclerosis - July 15, 2023 Category: Cardiology Authors: Minqi Xiong Zilong Zhang Jingang Cui Xiaoye Du Yu Chen Teng Zhang Source Type: research

Locked-in syndrome responding to endovascular treatment
Conclusions This study found that EVT was associated with favorable functional outcomes and decreased mortality among patients with LiS. Baseline pc-ASPECTS and pneumonia were independent predictors of outcomes.
Source: Journal of NeuroInterventional Surgery - July 14, 2023 Category: Neurosurgery Authors: Song, J., Huang, J., Li, L., Yang, J., Yue, C., Liu, S., Kong, W., Luo, X., Liao, J., Du, J., Song, B., Liu, J., Tian, X., Tan, X., Li, F., Zi, W. Tags: Open access, Clinical neurology Source Type: research

The contribution of genotype-guided selection of P2Y12 inhibitor on prognosis in ACS /CCS patients undergoing percutaneous coronary intervention: a retrospective cohort study
ConclusionsGenotype-guided selection of P2Y12 inhibitor made a very positive contribution on the prognosis in Chinese ACS/CCS patients undergoing PCI. Instead of intensifying antiplatelet strategies, conventional-dose clopidogrel could be recommended as P2Y12 inhibitor after weighing MACEs and bleeding events in CYP2C19 IM patients.
Source: European Journal of Clinical Pharmacology - July 14, 2023 Category: Drugs & Pharmacology Source Type: research

Herbal medicine as adjunctive therapy with antidepressants for post-stroke depression: a systematic review and network meta-analysis of randomized controlled trials
This study summarizes the latest evidence regarding the harms and benefits of herbal antidepressants.Methods: The literature searched from the Cochrane Library (using the OVID platform), Embase, PubMed, the China National Knowledge Infrastructure (CNKI), the Wan Fang Data Knowledge Service Platform, and the China Scientific Journal Database (VIP) from their inception to 18 August 2021, for randomized controlled trials of herbal medicine in adults with post-stroke depression, were included in this systematic review and network meta-analysis. The search was updated on 1 December 2022. To summarize the evidence, the frequenti...
Source: Frontiers in Pharmacology - July 14, 2023 Category: Drugs & Pharmacology Source Type: research

Effect-enhancing and toxicity-reducing effects of Chaihu Jia Longgu Muli decoction in the treatment of multimorbidity with depression: a systematic review and meta-analysis
CONCLUSIONS: CLMD combined with antidepressants enhances the effect of antidepressants and reduces their adverse reactions, performing a synergistic effect; it may be considered as an effective option in the treatment of MMD.PMID:37439185 | DOI:10.1080/13880209.2023.2228356
Source: Pharmaceutical Biology - July 13, 2023 Category: Drugs & Pharmacology Authors: Xurui Jia Jie Chen Ruiou Huang Dawei Wang Xing Wang Source Type: research

Vulnerable Carotid Plaque is Associated with An Increased Risk of Intracerebral Hemorrhage in Individuals at High Risk of Stroke: A Chinese Population-based Cohort Study
CONCLUSION: In Chinese individuals at high risk of stroke, vulnerable carotid artery plaques are associated with an increased risk of intracerebral hemorrhage independent of classical vascular risk factors, especially in female individuals.PMID:37438901 | DOI:10.2174/1567202620666230712114927
Source: Current Neurovascular Research - July 13, 2023 Category: Neurology Authors: Jie Li Ping Zhang Hong Chen Ting Qing Yanfen Wang Ju Zhou Xingyang Yi Chun Wang Source Type: research

External validation and comparison of clinical scores for predicting late seizures after intracerebral hemorrhage in Chinese patients
CONCLUSION: Our study showed that the CAVE, CAVS and LANE scores had similar AUCs for the occurrence of late seizures, but the LANE score had a relatively high PPV at the optimal cutoff score. Due to low evidence for using prophylactic antiseizure medications (ASM) in patients with ICH and poor availability of specialist stroke care in China, the LANE score with a cutoff score of 3 could be an applicable prediction tool in Chinese patients with ICH.PMID:37441984 | DOI:10.1016/j.yebeh.2023.109349
Source: Epilepsy and Behaviour - July 13, 2023 Category: Neurology Authors: Jiahe Lin Xianxian Li Jiahe Ye Guo Li Shanshan Huang Suiqiang Zhu Source Type: research

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