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AHA News: After Diabetes, Stroke and Heart Attack, She ' s Learning to ' Fight Smart '
THURSDAY, May 21, 2020 (American Heart Association News) -- Hyvelle Ferguson-Davis was reviewing paperwork at her office in Fort Lauderdale, Florida, when the headache started. It grew stronger and stronger and her eyes blurred, making it difficult...
Source: Drugs.com - Daily MedNews - May 21, 2020 Category: General Medicine Source Type: news

Detection of Asymptomatic Carotid Artery Stenosis in High-Risk Individuals of Stroke Using a Machine-Learning Algorithm
Publication date: December 2020Source: Chinese Medical Sciences Journal, Volume 35, Issue 4Author(s): Junxiong Yin, Cheng Yu, Lixia Wei, Chuanyong Yu, Hongxing Liu, Mingyang Du, Feng Sun, Chongjun Wang, Xiaoshan Wang
Source: Chinese Medical Sciences Journal - January 12, 2021 Category: General Medicine Source Type: research

Automatic Classification of the Korean Triage Acuity Scale in Simulated Emergency Rooms Using Speech Recognition and Natural Language Processing: a Proof of Concept Study
CONCLUSION: We demonstrated the potential of an automatic KTAS classification system using speech recognition models, machine learning and BERT-based classifiers.PMID:34254471 | DOI:10.3346/jkms.2021.36.e175
Source: J Korean Med Sci - July 13, 2021 Category: General Medicine Authors: Dongkyun Kim Jaehoon Oh Heeju Im Myeongseong Yoon Jiwoo Park Joohyun Lee Source Type: research

Interventions in outside-school hours childcare settings for promoting physical activity amongst schoolchildren aged 4 to 12 years
CONCLUSIONS: Although the review included nine trials, the evidence for how to increase children's physical activity in outside-school hours care settings remains limited, both in terms of certainty of evidence and magnitude of the effect. Of the types of interventions identified, when assessed using GRADE there was low-certainty evidence that multi-component interventions, with a specific physical activity goal may have a small increase in daily moderate-to-vigorous physical activity and a slight reduction in BMI. There was very low-certainty evidence that interventions increase cardiovascular fitness. By contrast there w...
Source: Cochrane Database of Systematic Reviews - October 25, 2021 Category: General Medicine Authors: Rosa Virgara Anna Phillips Lucy K Lewis Katherine Baldock Luke Wolfenden Ty Ferguson Mandy Richardson Anthony Okely Michael Beets Carol Maher Source Type: research

Subclinical Atrial Fibrillation: A Silent Threat with Uncertain Implications
Annu Rev Med. 2021 Nov 17. doi: 10.1146/annurev-med-042420-105906. Online ahead of print.ABSTRACTAtrial fibrillation (AF) is one of the most common cardiac arrhythmias. Implantable and wearable cardiac devices have enabled the detection of asymptomatic AF episodes-termed subclinical AF (SCAF). SCAF, the prevalence of which is likely significantly underestimated, is associated with increased cardiovascular and all-cause mortality and a significant stroke risk. Recent advances in machine learning, namely artificial intelligence-enabled ECG (AI-ECG), have enabled identification of patients at higher likelihood of SCAF. Levera...
Source: Annual Review of Medicine - November 17, 2021 Category: General Medicine Authors: Anthony H Kashou Demilade A Adedinsewo Peter A Noseworthy Source Type: research

AlzEye: longitudinal record-level linkage of ophthalmic imaging and hospital admissions of 353 157 patients in London, UK
Purpose Retinal signatures of systemic disease (‘oculomics’) are increasingly being revealed through a combination of high-resolution ophthalmic imaging and sophisticated modelling strategies. Progress is currently limited not mainly by technical issues, but by the lack of large labelled datasets, a sine qua non for deep learning. Such data are derived from prospective epidemiological studies, in which retinal imaging is typically unimodal, cross-sectional, of modest number and relates to cohorts, which are not enriched with subpopulations of interest, such as those with systemic disease. We thus linked longitu...
Source: BMJ Open - March 16, 2022 Category: General Medicine Authors: Wagner, S. K., Hughes, F., Cortina-Borja, M., Pontikos, N., Struyven, R., Liu, X., Montgomery, H., Alexander, D. C., Topol, E., Petersen, S. E., Balaskas, K., Hindley, J., Petzold, A., Rahi, J. S., Denniston, A. K., Keane, P. A. Tags: Open access, Ophthalmology Source Type: research

Dl-3-n-butylphthalide alleviates cognitive impairment in amyloid precursor protein/presenilin 1 transgenic mice by regulating the striatal-enriched protein tyrosine phosphatase/ERK/cAMP-response element-binding protein signaling pathway
In conclusion, the present study provided evidence to suggest that the new drug NBP improved amyloid-induced learning and memory deficits, likely through the regulation of the STEP/ERK/CREB pathway. The results revealed that NBP, as a multi-target drug, may exert a neuroprotective effect. Therefore, NBP may serve as an effective treatment for AD.PMID:35350668 | PMC:PMC8943801 | DOI:10.3892/etm.2022.11248
Source: Experimental and Therapeutic Medicine - March 30, 2022 Category: General Medicine Authors: Yan Zhao Wen-Qiang Yang Lu Yu Jing Yang Hai-Rong Zhu Lin Zhang Source Type: research

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