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Total 273 results found since Jan 2013.
What is Ondine ’ s Curse?
Discussion
Congenital central hypoventilation syndrome (CCHS) is an autosomal dominant with variable inheritance genetic disease caused by mutation in the Paired Like Homeobox B2 (PHOX2B) gene on chromosome 4. There are two other genes which may also cause CCHS. CCHS affects the chemoreceptor afferent ventilation pathways and is a neural crest migration problem of the autonomic nervous system. The incidence is unknown but a prevalence of 1 in 200,000 live births has been reported. Obviously it is a rarer phenomenon because of the general lethality of the syndrome.
Patients usually present at birth or soon afterwards, but o...
Source: PediatricEducation.org - August 15, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
050 Feasibility of an automated assessment to measure cognition and mood in the acute stroke setting
Discussion
Screening was adapted due to Covid pandemic and utilising remote consent and participa- tion allowed the project to continue.
Source: Journal of Neurology, Neurosurgery and Psychiatry - August 12, 2022 Category: Neurosurgery Authors: Bell, S., Harkness, K., Roman, M., Gardner, J., Richards, E., Howe, J., Sikaonga, M., Mirheidari, B., Christensen, H., Blackburn, D. Tags: Poster presentations Source Type: research
Using convolutional neural network to analyze brain MRI images for predicting functional outcomes of stroke
AbstractNowadays, the physicians usually predict functional outcomes of stroke based on clinical experiences and big data, so we wish to develop a model to accurately identify imaging features for predicting functional outcomes of stroke patients. Using magnetic resonance imaging of ischemic and hemorrhagic stroke patients, we developed and trained a VGG-16 convolutional neural network (CNN) to predict functional outcomes after 28-day hospitalization. A total of 44 individuals (24 men and 20 women) were recruited from Taoyuan General Hospital and China Medical University Hsinchu Hospital to enroll in the study. Based on â€...
Source: Medical and Biological Engineering and Computing - August 2, 2022 Category: Biomedical Engineering Source Type: research
IJERPH, Vol. 19, Pages 8995: Bridging the Gap between Clinical Service and Academic Education of Hand-Splinting Practice: Perspectives and Experiences of Thai Occupational Therapists
ch Thichanpiang
A gap in knowledge about current splinting practice exists between the educational program and clinical service. To bridge this gap, we investigated the perspectives and experiences of Thai occupational therapists regarding contemporary hand splinting practices in clinical use. A mixed-method study was designed. An explanatory sequential mixed methods design was used. In the first quantitative phase, a survey questionnaire was mailed to occupational therapists. The questions were regarding contemporary hand splinting practices in clinical use at seven hospitals in the capital city of Bangkok and outskir...
Source: International Journal of Environmental Research and Public Health - July 24, 2022 Category: Environmental Health Authors: Anuchart Kaunnil Veerawat Sansri Surachart Thongchoomsin Kannika Permpoonputtana Mandy Stanley Piyawat Trevittaya Chirathip Thawisuk Peeradech Thichanpiang Tags: Article Source Type: research
Pilot Report for Intracranial Hemorrhage Detection with Deep Learning Implanted Head Computed Tomography Images at Emergency Department
AbstractHemorrhagic stroke is a serious clinical condition that requires timely diagnosis. An artificial intelligence algorithm system called DeepCT can identify hemorrhagic lesions rapidly from non-contrast head computed tomography (NCCT) images and has received regulatory clearance. Â A non-controlled retrospective pilot clinical trial was conducted. Patients who received NCCT at the emergency department (ED) of Kaohsiung Veteran General Hospital were collected. From 2020 January-1st to April-30th, the physicians read NCCT images without DeepCT. From 2020May-1st to August-31st, the physicians were assisted by DeepCT. The...
Source: Journal of Medical Systems - June 8, 2022 Category: Information Technology Source Type: research
New Data From Two Large Studies Reinforce Effectiveness of Dual Pathway Inhibition (DPI) with XARELTO ® (rivaroxaban) Plus Aspirin in Patients with Coronary Artery Disease (CAD) and/or Peripheral Artery Disease (PAD)
RARITAN, N.J., May 23, 2022 – Findings from the XARELTO® (rivaroxaban) Phase 3 COMPASS Long-Term Open Label Extension (LTOLE) study and the XARELTO® in Combination with Acetylsalicylic Acid (XATOA) registry have been published in the European Society of Cardiology’s (ESC) European Heart Journal, Cardiovascular Pharmacotherapy. Additionally, the XATOA registry was presented at the American Congress of Cardiology’s 71st Annual Scientific Session (ACC.22). These studies provide further evidence supporting the role of dual pathway inhibition (DPI) with the XARELTO® vascular dose (2.5 mg twice daily plus aspirin 100 mg...
Source: Johnson and Johnson - May 23, 2022 Category: Pharmaceuticals Source Type: news
The Relationship Between Physician and Center Case Volume on Outcomes of TransCarotid Artery Revascularization
It has been suggested that the annual hospital volume of cases may affect the number of adverse events following carotid endarterectomy (CEA). Transfemoral carotid stenting (TFCAS) was found to have an extended learning curve with an estimated minimum of 25 cases for the success of the stenting procedure. One prior study indicated that transcarotid artery revascularization (TCAR) is being performed with excellent stroke and mortality rates even in the early stages of the surgeons ’ learning curve.
Source: Journal of Vascular Surgery - May 19, 2022 Category: Surgery Authors: Nadin Elsayed, Maryam Ali Khan, Claire B. Janssen, Mahmoud B. Malas Tags: IYSC: International Young Surgeons Competition Source Type: research
Can We Learn from Our Children About stroke? Effectiveness of a School-Based Educational Programme in Greece
Stroke is the second most common cause of death worldwide and the leading cause of chronic functional limitations.1 Without appropriate and timely care between the stroke symptom appearance and the treatment in acute stroke incidents, the ischemic brain ages 3.6 years for every hour of blood deprivation.2 Yet patients repeatedly arrive late to the hospital.3,4 The lack of public awareness about stroke symptoms has been reported in the literature as one of the main factors, causing this belated arrival to the hospital and hence the belated medical treatment.
Source: Journal of Stroke and Cerebrovascular Diseases - May 13, 2022 Category: Neurology Authors: Hariklia Proios, Maria Baskini, Christos Keramydas, Tatiana Pourliaka, Kalliopi Tsakpounidou Source Type: research
Data from New VOYAGER PAD Analyses at ACC.22 Reinforce Benefit of XARELTO ® (rivaroxaban) Plus Aspirin in Patients with Peripheral Artery Disease (PAD) and Various Co-Morbid Conditions
RARITAN, N.J., April 1, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from new analyses from the Phase 3 VOYAGER PAD clinical trial reinforcing the benefit of the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily plus aspirin 100 mg once daily) in reducing severe vascular events in patients with PAD after lower-extremity revascularization (LER), a procedure that restores blood flow to the legs. Data from the two analyses demonstrate the role that the XARELTO® vascular dose plays in PAD patients with and without chronic kidney disease (CKD) and in PAD patients with and ...
Source: Johnson and Johnson - April 1, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news
FAST-IT: Find A Simple Test -- In TIA (transient ischaemic attack): a prospective cohort study to develop a multivariable prediction model for diagnosis of TIA through proteomic discovery and candidate lipid mass spectrometry, neuroimaging and machine learning--study protocol
Introduction
Transient ischaemic attack (TIA) may be a warning sign of stroke and difficult to differentiate from minor stroke and TIA-mimics. Urgent evaluation and diagnosis is important as treating TIA early can prevent subsequent strokes. Recent improvements in mass spectrometer technology allow quantification of hundreds of plasma proteins and lipids, yielding large datasets that would benefit from different approaches including machine learning. Using plasma protein, lipid and radiological biomarkers, our study will develop predictive algorithms to distinguish TIA from minor stroke (positive control) and TIA-mimics (n...
Source: BMJ Open - April 1, 2022 Category: General Medicine Authors: Milton, A. G., Lau, S., Kremer, K. L., Rao, S. R., Mas, E., Snel, M. F., Trim, P. J., Sharma, D., Edwards, S., Jenkinson, M., Kleinig, T., Noschka, E., Hamilton-Bruce, M. A., Koblar, S. A. Tags: Open access, Health services research Source Type: research
AlzEye: longitudinal record-level linkage of ophthalmic imaging and hospital admissions of 353 157 patients in London, UK
Purpose
Retinal signatures of systemic disease (‘oculomics’) are increasingly being revealed through a combination of high-resolution ophthalmic imaging and sophisticated modelling strategies. Progress is currently limited not mainly by technical issues, but by the lack of large labelled datasets, a sine qua non for deep learning. Such data are derived from prospective epidemiological studies, in which retinal imaging is typically unimodal, cross-sectional, of modest number and relates to cohorts, which are not enriched with subpopulations of interest, such as those with systemic disease. We thus linked longitu...
Source: BMJ Open - March 16, 2022 Category: General Medicine Authors: Wagner, S. K., Hughes, F., Cortina-Borja, M., Pontikos, N., Struyven, R., Liu, X., Montgomery, H., Alexander, D. C., Topol, E., Petersen, S. E., Balaskas, K., Hindley, J., Petzold, A., Rahi, J. S., Denniston, A. K., Keane, P. A. Tags: Open access, Ophthalmology Source Type: research
How Virtual Reality Is Expanding Health Care
Clinicians can help patients recover from strokes while they’re anywhere in the world—even states or countries far away from each other—by using a combination of robotics and virtual-reality devices.
It’s happening at Georgia Institute of Technology, where Nick Housley runs the Sensorimotor Integration Lab. There, patients undergoing neurorehabilitation, including those recovering from a stroke, are outfitted with robotic devices called Motus, which are strapped to their arms and legs. The goal: to speed up recovery and assist with rehabilitation exercises. Patients and practitioners using the syste...
Source: TIME: Health - March 4, 2022 Category: Consumer Health News Authors: Sascha Brodsky Tags: Uncategorized healthscienceclimate Source Type: news
Prediction of Communication Impairment in Children With Bilateral Cerebral Palsy Using Multivariate Lesion- and Connectome-Based Approaches: Protocol for a Multicenter Prospective Cohort Study
DiscussionThe findings of the study may lead to the development of several translational tools that can individually predict communication impairment in children newly diagnosed with BCP to ensure that these children receive early, targeted therapeutic intervention before they begin school.Trial registrationThe study has been registered with the Chinese Clinical Trial Registry (ChiCTR2100049497).
Source: Frontiers in Human Neuroscience - January 31, 2022 Category: Neuroscience Source Type: research
Using Machine Learning to develop a short-form measure assessing 5 functions in patients with stroke
This study aimed to develop and validate a machine learning based short measure (the ML-5F) to assess 5 functions (activities of daily living (ADL), balance, upper extremity (UE) and lower extremity (LE) motor function, and mobility) in patients with stroke.Design: Secondary data from a previous study. A follow-up study assessed patients with stroke using the Barthel Index (BI), Postural Assessment Scale for Stroke (PASS), and Stroke Rehabilitation Assessment of Movement (STREAM) at hospital admission and discharge.
Source: Archives of Physical Medicine and Rehabilitation - December 30, 2021 Category: Rehabilitation Authors: Gong-Hong Lin, Chih-Ying Li, Ching-Fan Sheu, Chien-Yu Huang, Shih-Chieh Lee, Yu-Hui Huang, Ching-Lin Hsieh Source Type: research
