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Specialty: Biomedical Science
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Total 1574 results found since Jan 2013.
Clinical course and risk factors for sleep disturbance in patients with ischemic stroke
ConclusionThe prevalence rates of sleep disturbance before and during the acute and chronic stroke periods were 34.3%, 37.4%, and 29.7%, respectively. The incidence of stroke-related insomnia was 15.6%. Patients with insomnia before stroke may recover after the stroke. Atrial fibrillation, hypertension, and mood disturbance were associated with a higher risk of sleep disturbance in the acute stroke period, whereas low education and mood disturbance were associated with insomnia in the chronic stroke period.
Source: PLoS One - November 8, 2022 Category: Biomedical Science Authors: Hui-Ju Tsai Source Type: research
Clinical Differences Between Stroke and Stroke Mimics in Code Stroke Patients
CONCLUSION: Some clinical and neurological characteristics have been identified to help differentiate stroke mimics from true stroke. In particular, the likelihood of stroke tended to increase as the number of accompanying focal neurological deficits increased.PMID:35191231 | DOI:10.3346/jkms.2022.37.e54
Source: Journal of Korean Medical Science - February 22, 2022 Category: Biomedical Science Authors: Taekwon Kim Han-Yeong Jeong Gil Joon Suh Source Type: research
Short telomere length in blood leukocytes contributes to the presence of atherothrombotic stroke and hemorrhagic stroke and risk of post-stroke death
Conclusions—Shorter telomere length may serve as a potential marker for the presence of atherothrombotic and hemorrhagic stroke and for the risk of post-stroke death.
Source: Clinical Science - January 16, 2013 Category: Biomedical Science Authors: W Zhang, Y Chen, Y Wang, P Liu, M Zhang, C Zhang, F B Hu, R Hui Source Type: research
Sex differences in post-stroke cognitive decline: A population-based longitudinal study of nationally representative data
ConclusionFemales, in contrast to males, experience post-stroke cognitive deficits, particularly during early post-stroke period. Identifying the sex-specific stroke characteristics contributing to differences in post stroke cognitive decline may inform future strategies for reducing the burden of post-stroke cognitive impairment and dementia.
Source: PLoS One - May 6, 2022 Category: Biomedical Science Authors: Abdulaziz T. Bako Source Type: research
Neutrophil extracellular traps regulate ischemic stroke brain injury
In this study, we investigated mechanistic regulators of neutrophil extracellular trap (NET) formation in stroke and whether they contribute to stroke outcomes. NET-forming neutrophils were found throughout brain tissue of ischemic stroke patients, and elevated plasma NET biomarkers correlated with worse stroke outcomes. Additionally, we observed increased plasma and platelet surface–expressed high-mobility group box 1 (HMGB1) in stroke patients. Mechanistically, platelets were identified as the critical source of HMGB1 that caused NETs in the acute phase of stroke. Depletion of platelets or platelet-specific knockout of...
Source: Journal of Clinical Investigation - May 16, 2022 Category: Biomedical Science Authors: Frederik Denorme, Irina Portier, John L. Rustad, Mark J. Cody, Claudia V. de Araujo, Chieko Hoki, Matthew D. Alexander, Ramesh Grandhi, Mitchell R. Dyer, Matthew D. Neal, Jennifer J. Majersik, Christian C. Yost, Robert A. Campbell Source Type: research
Can we distinguish stroke and stroke mimics via red cell distribution width in young patients?
CONCLUSIONS: Red cell distribution width is a promising, rapid, easy and inexpensive parameter to distinguish young stroke from stroke mimics (such as epilepsy and MS) in young patients.
PMID: 26528336 [PubMed]
Source: Archives of Medical Science - November 4, 2015 Category: Biomedical Science Tags: Arch Med Sci Source Type: research
The Influence of Acute Hyperglycemia in an Animal Model of Lacunar Stroke That Is Induced by Artificial Particle Embolization.
In conclusion, acute hyperglycemia aggravated the neurologic outcomes in diffuse infarction, although it significantly reduced the size of the cerebral infarct and improved the neurologic deficits in lacunar stroke.
PMID: 27226775 [PubMed - in process]
Source: International Journal of Medical Sciences - May 27, 2016 Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Association of the Single Nucleotide Polymorphisms in microRNAs 130b, 200b, and 495 with Ischemic Stroke Susceptibility and Post-Stroke Mortality
This study included 523 ischemic stroke patients and 400 control subjects. We investigated the association of three miRNA SNPs (miR-130bT>C,miR-200bT>C, andmiR-495A>C) with ischemic stroke prevalence and post-stroke mortality. In the multivariate logistic regression, there was no statistically significant difference in the distribution ofmiR-130bT>C,miR-200bT>C, ormiR-495A>C between the ischemic stroke and control groups. In the subgroup analysis based on ischemic stroke subtype, themiR-200b CC genotype was less frequently found in the large-artery atherosclerosis stroke subtype compared with controls (TT+CT vs CC; adjuste...
Source: PLoS One - September 6, 2016 Category: Biomedical Science Authors: Jinkwon Kim Source Type: research
Pharmacological thrombolysis for acute ischemic stroke treatment: Gender differences in clinical risk factors
Conclusions Despite similarities in different areas of stroke care for both men and women, more women with diabetes, previous history of stroke and higher NIH scores are more likely to be excluded from thrombolytic therapy. Men with a previous history of stroke, hypertension and higher NIH scores are more likely to be excluded rtPA even after adjustment for confounding variables.
Source: Advances in Medical Sciences - October 3, 2017 Category: Biomedical Science Source Type: research
Pharmacological thrombolysis for acute ischemic stroke treatment: Gender differences in clinical risk factors.
CONCLUSIONS: Despite similarities in different areas of stroke care for both men and women, more women with diabetes, previous history of stroke and higher NIH scores are more likely to be excluded from thrombolytic therapy. Men with a previous history of stroke, hypertension and higher NIH scores are more likely to be excluded rtPA even after adjustment for confounding variables.
PMID: 28985592 [PubMed - as supplied by publisher]
Source: Advances in Medical Sciences - October 3, 2017 Category: Biomedical Science Authors: Colello MJ, Ivey LE, Gainey J, Faulkner RV, Johnson A, Brechtel L, Madeline L, Nathaniel TI Tags: Adv Med Sci Source Type: research
Pharmacological thrombolysis for acute ischemic stroke treatment: Gender differences in clinical risk factors
ConclusionsDespite similarities in different areas of stroke care for both men and women, more women with diabetes, previous history of stroke and higher NIH scores are more likely to be excluded from thrombolytic therapy. Men with a previous history of stroke, hypertension and higher NIH scores are more likely to be excluded rtPA even after adjustment for confounding variables.
Source: Advances in Medical Sciences - July 5, 2018 Category: Biomedical Science Source Type: research
