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Total 2105 results found since Jan 2013.

Linkage of blood cell division cycle 42 with T helper cells, and their correlation with anxiety, depression, and cognitive impairment in stroke patients
This study aimed to assess the correlation between blood CDC42 and Th cells, and their association with mental issues in stroke patients. Peripheral blood samples were obtained from 264 stroke patients and 50 controls. Then, serum CDC42 was measured by enzyme-linked immunosorbent assay, and Th1, Th2, and Th17 cells were detected by flow cytometry. Hospital Anxiety and Depression Scale (HADS) and Mini Mental State Examination (MMSE) were applied to patients. CDC42 was decreased (P<0.001), Th1 (P=0.013) and Th17 (P<0.001) cells were elevated, while Th2 cells (P=0.108) showed no difference in stroke patients compared to...
Source: Brazilian Journal of Medical and Biological Research - September 13, 2023 Category: Research Authors: Haifeng Ma Qing Chang Jujuan Jia Yaoyuan Zhang Gang Wang Yuanyuan Li Source Type: research

A Single Trial of Transcutaneous Electrical Nerve Stimulation (TENS) Improves Spasticity and Balance in Patients with Chronic Stroke.
This study shows that TENS provides an immediately effective means of reducing spasticity and of improving balance in chronic stroke patients. The present data may be useful to establish the standard parameters for TENS application in the clinical setting of stroke. PMID: 23419328 [PubMed - in process]
Source: The Tohoku Journal of Experimental Medicine - February 22, 2013 Category: Research Authors: Cho HY, Sung In T, Hun Cho K, Ho Song C Tags: Tohoku J Exp Med Source Type: research

Analysis of risk factors for first seizure after stroke in chinese patients.
Abstract The aim of this study is to assess related risk factors and predict early- and late-onset seizure after first-ever stroke. A total of 2474 consecutive patients with initial stroke in China from 1997 to 2007 were retrospectively investigated, in which, 24 clinical and radiological indexes were used for evaluation. Odds ratio (OR) and 95% confidence interval (CI) were calculated by logistic regression. A total of 232 (11.1%) of patients developed seizures during a mean follow-up period of 18 months, with 123 experiencing early-onset and 109 late-onset seizure. The independent risk factors for early-onset se...
Source: Biomed Res - December 5, 2013 Category: Research Authors: Wang G, Jia H, Chen C, Lang S, Liu X, Xia C, Sun Y, Zhang J Tags: Biomed Res Int Source Type: research

The Effects of Game-Based Breathing Exercise on Pulmonary Function in Stroke Patients: A Preliminary Study.
CONCLUSIONS These findings gave some indications that it may be feasible to include GBE in rehabilitation interventions with this population. PMID: 26098853 [PubMed - in process]
Source: Medical Science Monitor - June 26, 2015 Category: Research Tags: Med Sci Monit Source Type: research

Effectiveness and Safety of Autologous Bone Marrow Stromal Cells Transplantation After Ischemic Stroke: A Meta-Analysis.
CONCLUSIONS Although BM-MNCs/MSCs transplantation might generate some benefits in lowering the grade of impairment caused by ischemic stroke, large RCTs are required to further confirm the effectiveness of BM-MSCs/MNCs-based cell therapy and to optimize the conditions require for best therapeutic effects. PMID: 26215395 [PubMed - in process]
Source: Medical Science Monitor - August 1, 2015 Category: Research Tags: Med Sci Monit Source Type: research

Diagnostic TCD for intracranial stenosis in acute stroke patients: experience from a tertiary care stroke center in Karachi, Pakistan
Conclusions: This study indicates the poor sensitivity of TCD to be a reliable screening tool for the presence of ICAD in the South Asian population in a real life clinical setting.
Source: BMC Research Notes - August 11, 2015 Category: Research Authors: Ayeesha KamalHasan RehmanNasir MustafaBilal AhmedMohammad JanFaisal WadivallaSyed Kamran Source Type: research

Robot-Assisted Reach Training for Improving Upper Extremity Function of Chronic Stroke.
Abstract Stroke, as a major risk factor for chronic impairment of upper limb function, can severely restrict the activities of daily living. Recently, robotic devices have been used to enhance the functional upper extremity movement of stroke patients. The purpose of the current study was to assess whether a robot-assisted reach training program using a whole arm manipulator (WAM) could improve upper extremity kinematic performance and functional movement for chronic stroke patients. Using a single-group design, this study followed 10 people with chronic stroke (6 men, 61.5 years; Mini-Mental State Examination sco...
Source: The Tohoku Journal of Experimental Medicine - October 17, 2015 Category: Research Authors: Cho KH, Song WK Tags: Tohoku J Exp Med Source Type: research

Total atrial conduction time to predict occult atrial fibrillation after cryptogenic stroke.
CONCLUSION: Our data suggest that measurement of TACT could help to predict future AF detection in patients with cryptogenic stroke. The clinical importance of prolonged rhythm monitoring or indication of direct anticoagulation therapy after cryptogenic stroke based on TACT should be further investigated. PMID: 27541997 [PubMed - as supplied by publisher]
Source: Clin Med Res - August 18, 2016 Category: Research Authors: Müller P, Ivanov V, Kara K, Klein-Wiele O, Forkmann M, Piorkowski C, Blockhaus C, Dimitroulis D, Afzal S, Shin DI, Kelm M, Makimoto H, Mügge A Tags: Clin Res Cardiol Source Type: research

Relationship Between Carotid Stenosis and Infarct Volume in Ischemic Stroke Patients.
CONCLUSIONS Our findings indicate that the percentage of carotid artery stenosis could be useful in predicting the infarct volume of the stroke. PMID: 27984560 [PubMed - in process]
Source: Medical Science Monitor - December 18, 2016 Category: Research Tags: Med Sci Monit Source Type: research

Influence of miR-155 on Cell Apoptosis in Rats with Ischemic Stroke: Role of the Ras Homolog Enriched in Brain (Rheb)/mTOR Pathway.
CONCLUSIONS Inhibition of miR-155 may play protective roles in ischemic stroke by phosphorylating S6K through the Rheb/mTOR pathway. PMID: 28025572 [PubMed - in process]
Source: Medical Science Monitor - December 28, 2016 Category: Research Tags: Med Sci Monit Source Type: research

Role of Phosphorylated HDAC4 in Stroke-Induced Angiogenesis.
In this study, we report that phosphorylation of HDAC4 was remarkably upregulated after stroke and blockade of HDAC4 phosphorylation with GÖ6976 repressed stroke-induced angiogenesis. Phosphorylation of HDAC4 was also increased in endothelial cells hypoxia model and suppression of HDAC4 phosphorylation inhibited the tube formation and migration of endothelial cells in vitro. Furthermore, in addition to the inhibition of angiogenesis, blockade of HDAC4 phosphorylation suppressed the expression of genes downstream of HIF-VEGF signaling in vitro and in vivo. These data indicate that phosphorylated HDAC4 may serve as an impor...
Source: Biomed Res - January 28, 2017 Category: Research Authors: Liu J, Zhou X, Li Q, Zhou SM, Hu B, Hu GW, Niu X, Guo SC, Wang Y, Deng ZF Tags: Biomed Res Int Source Type: research