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Total 3622 results found since Jan 2013.

Association of Progression of Carotid Artery Wall Volume and Recurrent Transient Ischemic Attack or Stroke Clinical Sciences
Conclusions—The annual progression of carotid wall volume is independently associated with recurrent ischemic cerebrovascular events, and this measurement has added value for intraplaque hemorrhage and fibrous cap rupture in predicting future events.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Mingming Lu, Peng Peng, Yuanyuan Cui, Huiyu Qiao, Dongye Li, Jianming Cai, Xihai Zhao Tags: Clinical Studies, Magnetic Resonance Imaging (MRI), Atherosclerosis Original Contributions Source Type: research

Quantifying Infarct Growth and Secondary Injury Volumes Clinical Sciences
Conclusions—The contributions of IG and AD to lesion expansion can be measured separately over time through the use of image registration. This approach can be used to combine imaging outcome data from computed tomography and MRI.
Source: Stroke - June 25, 2018 Category: Neurology Authors: George W.J. Harston, Davide Carone, Fintan Sheerin, Mark Jenkinson, James Kennedy Tags: Imaging, Ischemic Stroke Original Contributions Source Type: research

Diagnostic and Prognostic Blood Biomarkers in Transient Ischemic Attack and Minor Ischemic Stroke: An Up-To-Date Narrative Review
Transient ischemic attack (TIA) is a brief episode of focal neurological deficit, lasting less than 24 hours, and reaching its climax usually within minutes. Patients with an even tiny ischemic brain lesion on imaging are considered, on tissue-based criteria, to have a minor ischemic stroke (MIS), usually with mild and non-disabling symptoms.1 Although a consensus clinical definition for MIS is currently lacking, 5 working definitions based on information from head computed tomography (CT) scan and clinical examination have been developed by the National Institute of Neurological Disorder and Stroke (NINDS) rt-PA stroke study Investigators.
Source: Journal of Stroke and Cerebrovascular Diseases - January 10, 2022 Category: Neurology Authors: Matteo Foschi, Marina Padroni, Samir Abu-Rumeileh, Ahmed Abdelhak, Michele Russo, Lucio D'Anna, Maria Guarino Tags: Review Article Source Type: research

Time to ct scan imaging after symptom onset among ischeamic stroke patients presenting to a quaternary hospital in ghana
This study sought to determine the time of onset of symptoms to the time a CT imaging was done among patients presenting with acute stroke at the Korle-Bu Teaching Hospital.
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2023 Category: Neurology Authors: F. Duodu, D. Brodie Mends, B. Agbinko-Djobalar, P. Pekyi-Boateng, M. Amerwornu, P Adjei, A Akpalu, K Nkromah Source Type: research

The Effects of Alteplase 3 to 6 Hours After Stroke in the EPITHET-DEFUSE Combined Dataset: Post Hoc Case-Control Study Original Contributions
Conclusions— The data provide further evidence that alteplase significantly attenuates infarct growth and increases reperfusion compared with placebo in the 3- to 6- hour time window in patients selected based on MR penumbral imaging. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00238537
Source: Stroke - December 24, 2012 Category: Neurology Authors: Ogata, T., Christensen, S., Nagakane, Y., Ma, H., Campbell, B. C. V., Churilov, L., Lansberg, M. G., Straka, M., De Silva, D. A., Mlynash, M., Bammer, R., Olivot, J.-M., Desmond, P. M., Albers, G. W., Davis, S. M., Donnan, G. A., for the EPITHET and DEFUS Tags: CT and MRI, Other imaging, Thrombolysis Original Contributions Source Type: research

Clinical Outcomes Strongly Associated With the Degree of Reperfusion Achieved in Target Mismatch Patients: Pooled Data from the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution Studies Clinical Sciences
Conclusion— The degree of reperfusion documented on perfusion-weighted imaging after reperfusion therapies corresponds closely with clinical outcomes in TMM patients. Reperfusion of ≥90% of the perfusion lesion is an appropriate goal for reperfusion therapies to aspire to.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Inoue, M., Mlynash, M., Straka, M., Kemp, S., Jovin, T. G., Tipirneni, A., Hamilton, S. A., Marks, M. P., Bammer, R., Lansberg, M. G., Albers, G. W., for the DEFUSE 1 and 2 Investigators Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging, Thrombolysis Clinical Sciences Source Type: research

'Risky' Stroke Prevention Procedure May Be Safe In Some Patients
A major study published in the Lancet Neurology, funded by the Medical Research Council (MRC) and the Stroke Association, has found that stenting in the carotid artery (in the neck) is as safe as carotid artery surgery at reducing stroke risk in some patients. The research, which was part of the International Carotid Stenting Study (ICSS), reveals that stenting is equally as safe as surgery in patients who show few signs of changes to brain tissue (known as white matter lesions) in a brain scan...
Source: Health News from Medical News Today - July 15, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Validating Imaging Biomarkers of Cerebral Edema in Patients With Severe Ischemic Stroke
Background: There is no validated neuroimaging marker for quantifying brain edema. We sought to test whether magnetic resonance imaging (MRI)–based metrics would reliably change during the early subacute period in a manner consistent with edema and whether they would correlate with relevant clinical endpoints.Methods: Serial MRI studies from patients in the Echoplanar Imaging Thrombolytic Evaluation Trial with initial diffusion-weighted imaging (DWI) lesion volume>82 cm3 were analyzed. Two independent readers outlined the hemisphere and lateral ventricle on the involved side and calculated respective volumes at baseline...
Source: Journal of Stroke and Cerebrovascular Diseases - February 13, 2012 Category: Neurology Authors: Albert J. Yoo, Kevin N. Sheth, W. Taylor Kimberly, Zeshan A. Chaudhry, Jordan J. Elm, Sven Jacobson, Stephen M. Davis, Geoffrey A. Donnan, Gregory W. Albers, Barney J. Stern, R. Gilberto González Tags: Original Articles Source Type: research

Fluorescent Molecular Peroxidation Products: A Prognostic Biomarker of Early Neurologic Deterioration After Thrombolysis Clinical Sciences
Conclusions— FMPPs might be a valuable biomarker of poor early neurological outcome and be related to the appearance of symptomatic intracranial hemorrhage in tissue plasminogen activator–treated patients, one of the most feared neurological complications after thrombolytic treatment of acute ischemic stroke.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Llombart, V., Dominguez, C., Bustamante, A., Rodriguez-Sureda, V., Martin-Gallan, P., Vilches, A., Garcia-Berrocoso, T., Penalba, A., Hernandez-Guillamon, M., Rubiera, M., Ribo, M., Eschenfelder, C., Giralt, D., Molina, C. A., Alvarez-Sabin, J., Rosell, A Tags: Cerebrovascular disease/stroke, Acute Cerebral Infarction, Intracerebral Hemorrhage, Thrombolysis, Oxidant stress Clinical Sciences Source Type: research

Nascent Deep Microbleeds and Stroke Recurrences
This study investigated the contributions of nascent deep MBs to stroke recurrence.Methods: We prospectively analyzed nascent deep MBs in patients admitted to our hospital who were treated for index strokes between April 2004 and November 2009. The number of nascent deep MBs was counted on T2∗-weighted MRI scans around 1 year after the index strokes, and compared to previous MRIs on admission. Stroke recurrence–free rate curves were generated using the Kaplan–Meier method using the log-rank test. The odds ratio for nascent deep MBs was derived using a multivariate logistic regression model that was based on recurren...
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2013 Category: Neurology Authors: Toshio Imaizumi, Shigeru Inamura, Ikuhide Kohama, Kazuhisa Yoshifuji, Tatsufumi Nomura, Katsuya Komatsu Tags: Original Articles Source Type: research

Investigating the Utility of Previously Developed Prediction Scores in Acute Ischemic Stroke Patients in the Stroke Belt
Conclusions: Our study demonstrated that although highly predictive of outcome in the original study design treatment groups, prediction scores may not generalize to all patient samples, highlighting the importance of validating prediction scores in diverse samples.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2014 Category: Neurology Authors: Amelia K. Boehme, Pawan V. Rawal, Michael J. Lyerly, Karen C. Albright, Reza Bavarsad Shahripour, Paola Palazzo, Niren Kapoor, Mohammad Alvi, J. Thomas Houston, Mark R. Harrigan, Luis Cava, April Sisson, Anne W. Alexandrov, Andrei V. Alexandrov Tags: Original Articles Source Type: research

Crossed Cerebellar Diaschisis Detected by Arterial Spin-Labeled Perfusion Magnetic Resonance Imaging in Subacute Ischemic Stroke
Conclusions: With advantages in easy acquisition and no radiation, ASL-MRI seems to be an ideal tool for the detection and follow-up of CCD.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2014 Category: Neurology Authors: Shuai Chen, Min Guan, Hao-Jun Lian, Li-Jia Ma, Jun-Kui Shang, Shuang He, Ming-Ming Ma, Mi-Lan Zhang, Zi-Yuan Li, Mei-Yun Wang, Da-Peng Shi, Jie-Wen Zhang Tags: Original Articles Source Type: research

Two-Layered Susceptibility Vessel Sign on 3-Tesla T2*-Weighted Imaging Is a Predictive Biomarker of Stroke Subtype Brief Reports
Conclusion— The specificity of 2-layered SVS for cardioembolism was high. It may be useful for predicting cardioembolism and for the management of patients with acute ischemic stroke.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Yamamoto, N., Satomi, J., Tada, Y., Harada, M., Izumi, Y., Nagahiro, S., Kaji, R. Tags: Computerized tomography and Magnetic Resonance Imaging Brief Reports Source Type: research

Network dysfunction in post-stroke aphasia
Recovery of language function after aphasic stroke is the product of activity in domain-general and domain-specific distributed brain networks. These may include left and right fronto-temporo-parietal, cingulo-opercular, and default mode networks. This functional MRI study investigated the effects of a previous left hemisphere stroke on brain activity during speech production in fifty-three patients. The results were related to twenty-four healthy participants. The analyses investigated not only local activity, but also functional connectivity both within and between distributed networks. Although activity within individua...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 14, 2015 Category: Neurosurgery Authors: Geranmayeh, F., Wise, R. Tags: Stroke, Radiology, Radiology (diagnostics) Thur 21, Parallel session 5: Therapeutics Source Type: research

Congenital Spinal Malformation and Stroke: Aneurysmal Dilatations and Bilateral Rotational Vertebral Artery Occlusion
A 30-year-old woman suffered from acute vertebrobasilar stroke. Cranial tomography (CT) scans showed multiple vertebral abnormalities suggestive of congenital spine malformation, and angiographic CT revealed aneurysmal dilatations (ADs) at segment V2 of both vertebral arteries (VAs). Dynamic neuroimaging tests including angiography and angio-CT were performed and showed occlusion of both VAs at the point of the ADs with contralateral rotation of the neck. The presence of a bony structure causing the artery compression was excluded and embolic phenomena originating at the AD was proposed as the likely source of stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - December 8, 2015 Category: Neurology Authors: Patricia de la Riva, Maria Teresa Martínez-Zabaleta, Edurne Pardo, Nicolás Samprón, Elisabet Mondragón-Rezola, Maialen Arruti González, Jose Ángel Larrea, José Félix Martí-Massó Tags: Case Studies Source Type: research