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Total 338 results found since Jan 2013.

Current Guidelines on Management of Amaurosis Fugax and Transient Ischemic Attacks
Asia Pac J Ophthalmol (Phila). 2022 Feb 24. doi: 10.1097/APO.0000000000000511. Online ahead of print.ABSTRACTTransient ischemic attack (TIA) is defined as a transient episode of neurological dysfunction resulting from focal brain, spinal cord, or retinal ischemia, without associated infarction. Consequently, a TIA encompasses amaurosis fugax (AF) that is a term used to denote momentary visual loss from transient retinal ischemia. In this review, we use the word TIA to refer to both cerebral TIAs (occurring in the brain) and AF (occurring in the retina). We summarize the key components of a comprehensive evaluation and mana...
Source: Atherosclerosis - February 25, 2022 Category: Cardiology Authors: Amir A Mbonde Cumara B O'Carroll Octaviana A Dulamea Daniela Anghel Brian W Chong Oana M Dumitrascu Source Type: research

Differences in retinal microvasculature between large artery atherosclerosis and small artery disease: an optical coherence tomography angiography study
Conclusions: We found LAA patients had significantly reduced DVC density compared with SAD; we also showed anterior LAA patients had significantly reduced SVC density compared with posterior LAA. These findings suggest retinal imaging has the potential to be used to detect microvasculature changes in subtypes of ischemic stroke.PMID:36620764 | PMC:PMC9816383 | DOI:10.3389/fnagi.2022.1053638
Source: Atherosclerosis - January 9, 2023 Category: Cardiology Authors: Kun Lu William Robert Kwapong Shuai Jiang Xuening Zhang Jianyang Xie Chen Ye Yuying Yan Le Cao Yitian Zhao Bo Wu Source Type: research

Systematic review of the relationship between Hollenhorst plaques and cerebrovascular events
CONCLUSION: The presence of asymptomatic retinal emboli indicates a risk of a cerebrovascular event when compared to patients with no plaques seen on fundoscopy. The evidence suggests that these patients warrant referral for medical optimization of cardiovascular risk factors. Currently, there is no recommendation to support carotid endarterectomy in patients with Hollenhorst plaques, or retinal emboli, and further studies are needed to assess this.PMID:36914563 | DOI:10.1177/17085381231163339
Source: Vascular - March 13, 2023 Category: Surgery Authors: Baker Moustafa Ghoneim Daniel Westby Mohamed Elsharkawi Marwa Said Stewart R Walsh Source Type: research

Adult-onset leukodystrophy with vanishing white matter: a case series of 19 patients
ConclusionsAO-LVWM presents varying clinical manifestations at onset, including stroke-like events. WM rarefaction is the most consistent diagnostic clue even in the latest onset cases. Spectroscopy and electrophysiological features are compatible with axon, rather than myelin, damage. Cerebral glucose metabolic abnormalities and retinal alterations can be present. LVWM might also be caused by a digenic inheritance affecting the eIF2B complex.
Source: Journal of Neurology - May 12, 2023 Category: Neurology Source Type: research

Efficacy and safety of glucagon-like peptide-1 agonists on macrovascular and microvascular events in type 2 diabetes mellitus: a metanalysis
Conclusions Treatment with GLP-1 agonists in DM patients is associated with a significant reduction of all cause and CV mortality.
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 28, 2017 Category: Nutrition Source Type: research

Occipital Blood brain barrier permeability is an independent predictor of visual outcome in type 2 diabetics, irrespective of the retinal barrier: a longitudinal study
This article is protected by copyright. All rights reserved.
Source: Journal of Neuroendocrinology - December 16, 2017 Category: Endocrinology Authors: Sulaiman I Abuhaiba, Miguel Cordeiro, Andre Amorim, Ângela Cruz, Bruno Quendera, Carlos Ferreira, Luisa Ribeiro, Rui Bernardes, Miguel Castelo‐Branco Tags: Original Article Source Type: research

Occipital blood ‐brain barrier permeability is an independent predictor of visual outcome in type 2 diabetes, irrespective of the retinal barrier: A longitudinal study
We report for the first time that occipital BBB permeability is an independent predictor of visual acuity at baseline, as well as at 12 and 24 months, in type 2 diabetics with established BRB leakage. Our results suggest that occipital BBB permeability might be an independent biomarker for visual impairment in patients with established BRB leakage.
Source: Journal of Neuroendocrinology - January 23, 2018 Category: Endocrinology Authors: S. I. Abuhaiba, M. Cordeiro, A. Amorim, Â. Cruz, B. Quendera, C. Ferreira, L. Ribeiro, R. Bernardes, M. Castelo‐Branco Tags: ORIGINAL ARTICLE Source Type: research

In the Pipeline-Ischemic Stroke: Retinal Microvascular Abnormalities Portend Ischemic Stroke, Study Finds
No abstract available
Source: Neurology Today - June 7, 2018 Category: Neurology Tags: Features Source Type: research

Serum Beta Carotene and Overall and Cause-Specific Mortality.
CONCLUSIONS: This study provides evidence that higher beta carotene biochemical status is associated with lower overall, cardiovascular disease, heart disease, stroke, cancer, and other causes of mortality. The dose-response associations over a 30-year period were not attenuated by adjustment for other important risk factors and support greater fruit and vegetable consumption as a means to increase beta carotene status and promote longevity. PMID: 30566060 [PubMed - in process]
Source: Circulation Research - December 7, 2018 Category: Cardiology Authors: Huang J, Weinstein SJ, Yu K, Männistö S, Albanes D Tags: Circ Res Source Type: research

Central retinal artery occlusion – a new, provisional treatment approach
The retinal ganglion cells infarcted in central retinal artery occlusion (CRAO) are the somata of the optic nerve axons, part of the central nervous system. Consequently, CRAO with inner retinal infarction is a small vessel stroke, usually with the devastating consequence of severe visual loss in the affected eye. At present, there is no generally accepted, evidence-based therapy of non-arteritic CRAO in contrast to ischemic cerebral stroke that has well accepted treatment protocols. Widely divergent and controversial therapeutic options for CRAO reflect the desperation of treating physicians and disparate conflicting studies.
Source: Survey of Ophthalmology - January 29, 2019 Category: Opthalmology Authors: Argyrios Chronopoulos, James S. Schutz Tags: Major review Source Type: research

Central retinal artery occlusion —A new, provisional treatment approach
The retinal ganglion cells infarcted in central retinal artery occlusion (CRAO) are the somata of the optic nerve axons, part of the central nervous system. Consequently, CRAO with inner retinal infarction is a small vessel stroke, usually with the devastating consequence of severe visual loss in the affected eye. At present, there is no generally accepted, evidence-based therapy of nonarteritic CRAO in contrast to ischemic cerebral stroke that has well-accepted treatment protocols. Widely divergent and controversial therapeutic options for CRAO reflect the desperation of treating physicians and disparate conflicting studies.
Source: Survey of Ophthalmology - January 28, 2019 Category: Opthalmology Authors: Argyrios Chronopoulos, James S. Schutz Tags: Major review Source Type: research

What Causes Facial Nerve Palsy?
Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - June 3, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news