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Total 344 results found since Jan 2013.
Attenuation in Proinflammatory Factors and Reduction in Neuronal Cell Apoptosis and Cerebral Vasospasm by Minocycline during Early Phase after Subarachnoid Hemorrhage in the Rat
CONCLUSIONS: Microglia may play an important role to regulate neuronal cell apoptosis and cerebral vasospasm through inhibiting inflammation at an early phase after SAH in the rat.PMID:34912890 | PMC:PMC8668279 | DOI:10.1155/2021/5545727
Source: Biomed Res - December 16, 2021 Category: Research Authors: Chia-Li Chung Hung-Pei Tsai Yu-Hua Huang Shu-Chuan Wu Chee-Yin Chai Aij-Lie Kwan Source Type: research
IJERPH, Vol. 19, Pages 2278: The Impacts of COVID-19 on Healthcare Quality in Tertiary Medical Centers & mdash;A Retrospective Study on Data from Taiwan Clinical Performance Indicators System
IJERPH, Vol. 19, Pages 2278: The Impacts of COVID-19 on Healthcare Quality in Tertiary Medical Centers—A Retrospective Study on Data from Taiwan Clinical Performance Indicators System
International Journal of Environmental Research and Public Health doi: 10.3390/ijerph19042278
Authors:
Shih-An Liu
Chieh-Liang Wu
I-Ju Chou
Pa-Chun Wang
Chia-Ling Hsu
Chia-Pei Chen
To date, COVID-19 is by far the most impactful contagious disease of the 21st century and it has had a devastating effect on public health in countries around the globe. Elective medical services have declined markedly since the outbreak...
Source: International Journal of Environmental Research and Public Health - February 17, 2022 Category: Environmental Health Authors: Shih-An Liu Chieh-Liang Wu I-Ju Chou Pa-Chun Wang Chia-Ling Hsu Chia-Pei Chen Tags: Article Source Type: research
Virtual Rehabilitation of Elbow Flexion Following Nerve Transfer Reconstruction for Brachial Plexus Injuries Using the Single-Joint Hybrid Assisted Limb
CONCLUSION: HAL training accelerated patients' learning to convert the original muscle function into elbow flexion following NT by replicating elbow flexion during the pre-MUP detection stage and shortening the rehabilitation time.TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.PMID:35434571 | PMC:PMC9005380 | DOI:10.1016/j.jhsg.2021.12.005
Source: Hand Surgery - April 18, 2022 Category: Surgery Authors: Kazuteru Doi Dawn Sinn Yii Chia Yasunori Hattori Sotetsu Sakamoto Source Type: research
Immunoregulation of Ghrelin in neurocognitive sequelae associated with COVID-19: an in silico investigation
In this study, we explored, by bioinformatics approaches, the interaction between the multiple inflammatory agents involved in SARS-CoV-2 and Ghrelin (Ghre) together with its receptor GHSR-1A, which are described as anti-inflammatory mediators, in order to investigate what could trigger the hyper-inflammatory response in some SARS-CoV-2 patients. In our analysis, we found several interactions of Ghre and GHSR-1A with SARS-CoV-2 interacting human genes. We observed a correlation between Ghre, angiotensin-converting enzyme 2 ACE2, toll-like receptors 9 (TLR9), and Acidic chitinase (CHIA), whereas its receptor GHSR-1A interac...
Source: Gene - June 9, 2022 Category: Genetics & Stem Cells Authors: Cristina Russo Giovanna Morello Giuliana Mannino Antonella Russo Lucia Malaguarnera Source Type: research
Sex Difference in the Associations among Obesity-Related Indices with Incident Hypertension in a Large Taiwanese Population Follow-Up Study
In conclusion, the studied obesity-related indices were found to be predictors of incident hypertension, and there were differences in the associations between the male and female participants. Our findings may imply that reducing body weight may be associated with a lower risk of developing hypertension.PMID:35743756 | DOI:10.3390/jpm12060972
Source: Atherosclerosis - June 24, 2022 Category: Cardiology Authors: Wen-Chi Lee Pei-Yu Wu Jiun-Chi Huang Yi-Chun Tsai Yi-Wen Chiu Szu-Chia Chen Jer-Ming Chang Hung-Chun Chen Source Type: research
Impaired renal function and mortalities in acute heart failure with different phenotypes
ConclusionsOn-admission IRF was independently predictive of long-term mortality in patients hospitalized for HF, irrespective of HF phenotypes. Furthermore, IRF was also associated with short-term mortality in HFrEF and HFmrEF, but not in HFpEF.
Source: ESC Heart Failure - June 17, 2022 Category: Cardiology Authors: Wei ‐Ming Huang,
Hao‐Chih Chang,
Ching‐Wei Lee,
Chi‐Jung Huang,
Wen‐Chung Yu,
Hao‐Min Cheng,
Chao‐Yu Guo,
Chern‐En Chiang,
Chen‐Huan Chen,
Shih‐Hsien Sung Tags: Original Article Source Type: research
Dyslipidemia Increases the Risk of Incident Hypertension in a Large Taiwanese Population Follow-Up Study
In this study, we investigated correlations between lipid profiles, including triglycerides, total cholesterol (Chol), high-and low-density lipoprotein cholesterol (HDL-C/LDL-C), and Chol/HDL-C, and baseline and incident hypertension. A total of 26,965 subjects with 4 years of follow-up data were enrolled from the Taiwan Biobank. In the cross-sectional cohort, associations between the prevalence of hypertension and lipid profiles were examined in all study participants (n = 26,965). In the longitudinal cohort, these associations were further assessed in the participants without baseline hypertension (n = 21,454). Multivari...
Source: Atherosclerosis - August 26, 2022 Category: Cardiology Authors: Yu-Hsuan Lin Yi-Hsueh Liu Da-Wei Wu Ho-Ming Su Szu-Chia Chen Source Type: research
Trends in diabetes-related complications in Singapore, 2013 –2020: A registry-based study
ConclusionWe found that DM and its complications represent an important challenge for healthcare in Singapore. Improvements in the trends of DM macrovascular complications were observed. However, trends in DM microvascular complications remain a cause for concern.
Source: PLoS One - October 11, 2022 Category: Biomedical Science Authors: Joshua Kuan Tan Source Type: research
Burdens on caregivers of patients with stroke during a pandemic: relationships with support satisfaction, psychological distress, and fear of COVID-19
Caregivers have faced unprecedented circumstances throughout the COVID-19 pandemic, but previous research only minimally addresses the caregivers' burden. Therefore, this study aimed to investigate the relatio...
Source: BMC Geriatrics - December 13, 2022 Category: Geriatrics Authors: Chieh-hsiu Liu, Yi-Jung Chen, Jung-Sheng Chen, Chia-Wei Fan, Meng-Tsang Hsieh, Chung-Ying Lin and Amir H. Pakpour Tags: Research Source Type: research
IJERPH, Vol. 20, Pages 3065: Developmental Trajectories and Predictors of Incident Dementia among Elderly Taiwanese People: A 14-Year Longitudinal Study
uey Bai
The aim of this study was to identify dementia trajectories and their associated predictors among elderly Taiwanese people over a 14-year period using a nationwide representative longitudinal study. This retrospective cohort study was performed using the National Health Insurance Research Database. Group-based trajectory modeling (GBTM) was used to distinguish the specific trajectory groups of incident dementia during 2000–2013. All 42,407 patients were classified by GBTM to identify the trajectory of incident dementia, which included high- (n = 11,637, 29.0%), moderate- (n = 19,036, 44.9%), and l...
Source: International Journal of Environmental Research and Public Health - February 9, 2023 Category: Environmental Health Authors: Yen-Chun Fan Sheng-Feng Lin Chia-Chi Chou Chyi-Huey Bai Tags: Article Source Type: research
Risk of Major Cardiovascular Disease after Exposure to Contrast Media: A Nationwide Population-Based Cohort Study on Dialysis Patients
Metabolites. 2023 Feb 13;13(2):266. doi: 10.3390/metabo13020266.ABSTRACTContrast associated kidney injury is caused by side effects of iodinated contrast media (ICM), including inflammation. Chronic inflammation among dialysis patient contributes to atherosclerosis, which leads to simultaneous conditions of the kidney, brain, and vasculature. Data to investigate the pathologic effects of ICM on cardiovascular complications in dialysis patients are lacking. Dialysis patients who had been exposed to ICM from computed tomography (ICM-CT) were allocated as the ICM-CT cohort (N = 3751), whereas dialysis patients without ICM exp...
Source: Atherosclerosis - February 25, 2023 Category: Cardiology Authors: Shih-Ting Huang Tung-Min Yu Chia-Hsin Chen Yun-Chung Cheng Ya-Wen Chuang Cheng-Hsu Cheng Jia-Sin Liu Chih-Cheng Hsu Ming-Ju Wu Source Type: research
The Impact of Complete Revascularization in Symptomatic Severe Left Ventricular Dysfunction between Coronary Artery Bypass Graft and Percutaneous Coronary Intervention
CONCLUSIONS: In patients with symptomatic (NYHA class ≥ 3) severe LV dysfunction and CAD, CABG brought less HF admission when compared to patients in the PCI group, but this did not differ when compared to the complete revascularization subgroup. Therefore, an extensive revascularization, achieved by CABG or PCI, is associated with a lower HF hospitalization rate during the 3-yearfollow-up period in such populations.PMID:36896424 | PMC:PMC9991473 | DOI:10.1155/2023/9226722
Source: Cardiology Research and Practice - March 10, 2023 Category: Cardiology Authors: Hsiu-Yu Fang Yen-Nan Fang Yin-Chia Chen Jiunn-Jye Sheu Wei-Chieh Lee Source Type: research
