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Drug: Melatonin

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Total 139 results found since Jan 2013.

Melatonin Receptor Agonists for Treating Delirium in Elderly Patients with Acute Stroke
Conclusions: Melatonin receptor agonists may be effective for the treatment of delirium in elderly patients with acute stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - September 27, 2012 Category: Neurology Authors: Tsuyoshi Ohta, Kenichi Murao, Kosuke Miyake, Koichiro Takemoto Tags: Original Articles Source Type: research

How People With Diabetes Can Lower Stroke Risk
After spending nearly two decades trying to manage her Type 2 diabetes, Agnes Czuchlewski landed in the emergency room in 2015, with news that she’d just experienced a heart attack. She also learned that she had metabolic syndrome, a cluster of conditions that includes diabetes but also brings higher risk of heart disease and stroke. “Because I needed to lose quite a bit of weight when I was first diagnosed, I was focused on the number I saw on the scale, and then on my blood-sugar numbers,” recalls Czuchlewski, 68, who lives in New York City. “I didn’t realize other numbers came into play, li...
Source: TIME: Health - November 10, 2022 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized Disease healthscienceclimate Source Type: news

Interaction of night shift work with polymorphism in melatonin receptor 1B gene on incident stroke
Conclusions These results suggest that MTNR1B rs10830963 may potentially modify the associations between night shift work and incident stroke. by Chen Y, Yang L, Liang Y, He Z, Ai Q-YH, Chen W, Xue H, Zhou M, Wang Y, Ma H, Geng Q. doi:10.5271/sjweh.4022
Source: Scandinavian Journal of Work, Environment and Health - March 28, 2022 Category: Occupational Health Tags: Original article Source Type: research

Melatonin regulates microglial polarization and protects against ischemic stroke-induced brain injury in mice
Exp Neurol. 2023 Jun 8:114464. doi: 10.1016/j.expneurol.2023.114464. Online ahead of print.ABSTRACTIschemic stroke is a leading cause of mortality and morbidity worldwide, with neuroinflammation playing a key role in its pathophysiology. Microglia, the primary immune cells in the brain, undergo rapid activation and phenotypic polarization, which are crucial for regulating neuroinflammatory responses following ischemic stroke. Melatonin is a promising neuroprotective agent that can regulate microglial polarization in central nervous system (CNS) diseases. However, the specific mechanism underlying the neuroprotective effect...
Source: Experimental Neurology - June 10, 2023 Category: Neurology Authors: Donghai Li Tianpeng He Yue Zhang Junru Liu Haiyu Zhao Dongliang Wang Quanchao Wang Yuan Yuan Shengxiang Zhang Source Type: research