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Total 1186 results found since Jan 2013.

Imaging assessment of acute ischaemic stroke - a review of radiological methods.
Abstract Acute ischaemic stroke is the second largest cause of death worldwide and a cause of major physical and psychological morbidity. Current evidence based treatment includes intravenous thrombolysis (IVT) and mechanical thrombectomy (MT), both requiring careful patient selection and to be administered as quickly as possible within a limited time window from symptom onset. Imaging plays a crucial role identifying patients who may benefit from MT or IVT whilst excluding those that maybe harmed. For IVT, imaging must as a minimum exclude haemorrhage, stroke mimics and provide an estimate of non-viable brain. Fo...
Source: The British Journal of Radiology - November 16, 2017 Category: Radiology Authors: Smith A, Rowland Hill C Tags: Br J Radiol Source Type: research

Cerebral microbleeds and intracranial haemorrhage risk in patients anticoagulated for atrial fibrillation after acute ischaemic stroke or transient ischaemic attack (CROMIS-2): a multicentre observational cohort study
This study is registered with ClinicalTrials.gov, number NCT02513316. Findings Between Aug 4, 2011, and July 31, 2015, we recruited 1490 participants of whom follow-up data were available for 1447 (97%), over a mean period of 850 days (SD 373; 3366 patient-years). The symptomatic intracranial haemorrhage rate in patients with cerebral microbleeds was 9·8 per 1000 patient-years (95% CI 4·0–20·3) compared with 2·6 per 1000 patient-years (95% CI 1·1–5·4) in those without cerebral microbleeds (adjusted hazard ratio 3·67, 95% CI 1·27–10·60). Compared with the HAS-BLED score alone (C-index 0·41, 95% CI 0·29–0Â...
Source: The Lancet Neurology - May 16, 2018 Category: Neurology Source Type: research

Effects of dry needling on post-stroke spasticity, motor function and stability limits: a randomised clinical trial.
CONCLUSIONS: The inclusion of deep dry needling into a treatment session following the Bobath concept was effective at decreasing spasticity and improving balance, range of motion and the accuracy of maintaining stability in patients who had experienced a stroke. TRIAL REGISTRATION NUMBER: NCT02579291. PMID: 29986902 [PubMed - as supplied by publisher]
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - July 9, 2018 Category: Complementary Medicine Authors: Sánchez-Mila Z, Salom-Moreno J, Fernández-de-Las-Peñas C Tags: Acupunct Med Source Type: research

Barriers to a software reminder system for risk assessment of stroke in atrial fibrillation: a process evaluation of a cluster randomised trial in general practice.
CONCLUSION: Automated risk assessment for stroke in atrial fibrillation and prompting during consultations are feasible and generally acceptable, but did not overcome concerns about frailty and risk of haemorrhage as barriers to anticoagulant uptake. PMID: 30397015 [PubMed - as supplied by publisher]
Source: The British Journal of General Practice - November 5, 2018 Category: Primary Care Authors: Holt TA, Dalton AR, Kirkpatrick S, Hislop J, Marshall T, Fay M, Qureshi N, Lasserson DS, Kearley K, Mollison J, Yu LM, Fitzmaurice D, Hobbs FR Tags: Br J Gen Pract Source Type: research

Mitochondrial protective effect of neferine through the modulation of Nrf2 signalling in ischemic stroke
Conclusions and implicationsThe data in this study demonstrated that Nef might have therapeutic potential for ischemic stroke and may exert its protective role through mitochondrial protection. In addition, this protection might be attributed to the modulation of Nrf2 signalling.
Source: British Journal of Pharmacology - November 10, 2018 Category: Drugs & Pharmacology Authors: Chuanhong Wu, Jianxin Chen, Ruocong Yang, Feipeng Duan, Shaojing Li, Xiuping Chen Tags: RESEARCH PAPER Source Type: research

The acute stroke unit as a meaningful space: The lived experience of healthcare practitioners.
Abstract This hermeneutic phenomenological study was undertaken in response to the recent re-organization of stroke unit provision in the United Kingdom. Through the analysis of four acute stroke unit practitioners' subjective accounts, the acute stroke unit emerged as a dynamic, meaningful space, where they experienced authenticity and belonging. The findings showed how these practitioners navigated their way through the space, thriving, and/or surviving its' associated vulnerabilities. They offer a different gaze on which to attend to the complexity and challenge that is interwoven with health professionals' flo...
Source: Health and Place - March 4, 2019 Category: Environmental Health Authors: Suddick KM, Cross V, Vuoskoski P, Stew G, Galvin KT Tags: Health Place Source Type: research

Generalizing post-stroke prognoses from research data to clinical data
Publication date: Available online 14 October 2019Source: NeuroImage: ClinicalAuthor(s): Robert Loughnan, Diego L. Lorca-Puls, Andrea Gajardo-Vidal, Valeria Espejo-Videla, Céline R. Gillebert, Dante Mantini, Cathy J. Price, Thomas M.H. HopeAbstractAround a third of stroke survivors suffer from acquired language disorders (aphasia), but current medicine cannot predict whether or when they might recover. Prognostic research in this area increasingly draws on datasets associating structural brain imaging data with outcome scores for ever-larger samples of stroke patients. The aim is to learn brain-behavior trends from these ...
Source: NeuroImage: Clinical - October 15, 2019 Category: Radiology Source Type: research

Stroke warning syndromes.
Abstract It is important for physicians to be aware of stroke warning syndromes because, although rare, there is a high associated risk of subsequent ischaemic infarction. Stroke warning syndromes present as stereotypical, recurrent transient episodes of focal neurological deficit, in the absence of cortical signs, occurring within a short period of time. They are broadly divided into two main subtypes, based on vascular territory: capsular warning syndrome and pontine warning syndrome. The exact underlying pathophysiology related to stroke warning syndromes is incompletely established, but proposed pathophysiolog...
Source: British Journal of Hospital Medicine - January 1, 2020 Category: Internal Medicine Authors: Sen A, Birns J, Bhalla A Tags: Br J Hosp Med (Lond) Source Type: research

Post-needling soreness and trigger point dry needling for hemiplegic shoulder pain following stroke.
CONCLUSION: This trial found that 50% of stroke patients receiving DN experienced post-needling induced pain, a side effect that almost disappeared 72 h after the intervention without any additional therapeutic action. In addition, the inclusion of TrP-DN into a rehabilitation session was effective at decreasing shoulder pain in these patients. PMID: 32009422 [PubMed - as supplied by publisher]
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - February 2, 2020 Category: Complementary Medicine Authors: Mendigutía-Gómez A, Quintana-García MT, Martín-Sevilla M, de Lorenzo-Barrientos D, Rodríguez-Jiménez J, Fernández-de-Las-Peñas C, Arias-Buría JL Tags: Acupunct Med Source Type: research

Discrepancies between current and ideal endovascular stroke treatment practice in Europe and North America: Results from UNMASK EVT, a multidisciplinary survey.
CONCLUSION: In the majority of North American states/provinces and European countries covered in this study, the discrepancy between endovascular therapy decisions under current local resources and assumed ideal conditions seems to be small, even in countries with a limited economic status and healthcare infrastructure. PMID: 32077353 [PubMed - as supplied by publisher]
Source: Interventional Neuroradiology - February 22, 2020 Category: Radiology Tags: Interv Neuroradiol Source Type: research

Timing of procedural stroke and death in asymptomatic patients undergoing carotid endarterectomy: individual patient analysis from four RCTs.
CONCLUSION: At least half of the procedural strokes in this study were ischaemic and ipsilateral to the treated artery. Half of all procedural complications occurred on the day of surgery, but one-third after day 3 when many patients had been discharged. PMID: 32162310 [PubMed - as supplied by publisher]
Source: The British Journal of Surgery - March 11, 2020 Category: Surgery Authors: Poorthuis MHF, Bulbulia R, Morris DR, Pan H, Rothwell PM, Algra A, Becquemin JP, Bonati LH, Brott TG, Brown MM, Calvet D, Eckstein HH, Fraedrich G, Gregson J, Greving JP, Hendrikse J, Howard G, Jansen O, Mas JL, Lewis SC, de Borst GJ, Halliday A, Carotid Tags: Br J Surg Source Type: research

Critical care management of the patient with an acute ischaemic stroke
This article reviews the current critical care management and neuro-therapeutic options after an acute ischaemic stroke.PMID:33512282 | DOI:10.12968/hmed.2020.0123
Source: British Journal of Hospital Medicine - January 29, 2021 Category: Internal Medicine Authors: Randeep K Mullhi Naginder Singh Tonny Veenith Source Type: research