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Total 478 results found since Jan 2013.

Preventable Cases of Oral Anticoagulant-Induced Bleeding: Data From the Spontaneous Reporting System
Conclusion: Our findings describe the most reported risk factors for preventability of oral anticoagulant-induced bleedings. These factors may be useful for targeting interventions to improve pharmacovigilance activities in our regional territory and to reduce the burden of medication errors and inappropriate prescription. Introduction Oral anticoagulant therapy is widely used for the prevention of stroke and systemic embolism in patients with atrial fibrillation, or for the prevention and treatment of deep vein thrombosis and pulmonary embolism (Raj et al., 1994; Monaco et al., 2017). Oral anticoagulants can be di...
Source: Frontiers in Pharmacology - April 29, 2019 Category: Drugs & Pharmacology Source Type: research

Interaction between a haptoglobin genetic variant and coronary artery disease (CAD) risk factors on CAD severity in Singaporean Chinese population
ConclusionHP genetic variant is not associated with CAD severity and mortality in the general population. However, hypertensive individuals with the rs217181 T allele associated with higher Hp levels had more severe CAD while non ‐hypertensive individuals with the same allele had lower risk for mortality in the Chinese population.
Source: Molecular Genetics & Genomic Medicine - August 12, 2020 Category: Genetics & Stem Cells Authors: Xuling Chang, Rajkumar Dorajoo, Yi Han, Ling Wang, Jianjun Liu, Chiea ‐Chuen Khor, Adrian F. Low, Mark Yan‐Yee Chan, Jian‐Min Yuan, Woon‐Puay Koh, Yechiel Friedlander, Chew‐Kiat Heng Tags: ORIGINAL ARTICLE Source Type: research

Predictors and outcomes of high-flow nasal cannula failure following extubation: A multicentre observational study
CONCLUSION: Post-extubation HFNC failure, especially in patients with stroke as a comorbidity, remains a clinical challenge and predicts poorer clinical outcomes. Our observational study highlights the need for future prospective trials to better identify patients at high risk of post-extubation HFNC failure.PMID:34195753
Source: Ann Acad Med Singapo... - July 1, 2021 Category: General Medicine Authors: Amit Kansal Shekhar Dhanvijay Andrew Li Jason Phua Matthew Edward Cove Wei Jun Dan Ong Ser Hon Puah Vicky Ng Qiao Li Tan Julipie Sumampong Manalansan Michael Sharey Nocon Zamora Michael Camba Vidanes Juliet Tolentino Sahagun Juvel Taculod Addy Yong Hui Ta Source Type: research