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Specialty: Cardiology
Condition: Atrial Fibrillation
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Total 6926 results found since Jan 2013.
Peri- and Post-procedural Anticoagulation with Left Atrial Appendage Occlusion Devices
Heart Int. 2023 Jun 21;17(1):54-59. doi: 10.17925/HI.2023.17.1.54. eCollection 2023.ABSTRACTIn patients with atrial fibrillation and high stroke risk, anticoagulation with direct oral anticoagulants or vitamin K antagonists is the standard of care for stroke prevention. The benefit of anticoagulation is driven by attenuating the risk of thrombus formation in the left atrial appendage. Percutaneous left atrial appendage occlusion offers an alternative therapeutic strategy for stroke prevention in patients with high bleeding risk or contraindications for long-term anticoagulation. This review of the current literature deline...
Source: Heart International - July 17, 2023 Category: Cardiology Authors: Pradyumna Agasthi Sai Harika Pujari Source Type: research
ICAM-1 and VCAM-1: gatekeepers in various inflammatory and cardiovascular disorders
Clin Chim Acta. 2023 Jul 11:117487. doi: 10.1016/j.cca.2023.117487. Online ahead of print.ABSTRACTLeukocyte migration from the vascular compartment is critical fornormal lymphocyte recirculation in specific tissues and immune response in inflammatory locations. Leukocyte recruitment, migration to inflammatory areas, and targeting in the extravascular space are caused by cellular stimulation and local expression of adhesion molecules. Intercellular adhesion molecule 1 (ICAM-1) and Vascular cell adhesion molecule 1 (VCAM-1) belong to the immunoglobulin superfamily of cell adhesion molecules with a crucial role in mediating t...
Source: Atherosclerosis - July 13, 2023 Category: Cardiology Authors: Varinder Singh Rupinder Kaur Pratima Kumari Chirag Pasricha Ravinder Singh Source Type: research
Demographics, Risk Factors, and Etiology of Posterior Cerebral Artery Stroke Causing Homonymous Hemianopia
CONCLUSIONS: Most patients in our PCA cohort had multiple conventional stroke risk factors, a finding not previously documented. Mean age at stroke onset and AF frequency were lower than in our ICA/MCA cohort, in agreement with previous studies. As some other studies have found, nearly 1/3 of strokes were attributed to cardioaortic embolism. Within that group, AF was often a poststroke diagnosis, a finding not previously highlighted. Compared with earlier studies, a relatively high portion of strokes were of undetermined etiology and of other determined etiologies, including stroke after endovascular or surgical interventi...
Source: Atherosclerosis - July 12, 2023 Category: Cardiology Authors: Elaine A Liu Sadhana Murali Roberto Rivera-de Choudens Jonathan D Trobe Source Type: research
NOAC Therapy According to CHA2DS2-VASc Without Atrial Fibrillation: A Systematic Review
Cardiol Rev. 2023 Jul 11. doi: 10.1097/CRD.0000000000000570. Online ahead of print.ABSTRACTAccording to Quality-Adjusted Life Expectancy, novel oral anticoagulant therapy is preferred when the stroke risk is higher than 0.9% per year. CHA2DS2-VASc is a tool to select those patients at high risk for stroke due to atherosclerosis and atrial cardiopathy, who could benefit from anticoagulation even in sinus rhythm. Systematic electronic database searches were conducted using Pubmed and Scopus. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement 2020 was followed. Thirteen studies were included, com...
Source: Atherosclerosis - July 11, 2023 Category: Cardiology Authors: Riccardo Maddalena Source Type: research
Percutaneous Left Atrial Appendage Closure Among Patients With Diabetes (Insights from a National Database)
Atrial fibrillation is a major risk factor for stroke. Left atrial appendage closure (LAAC) has emerged as an alternative to anticoagulation for patients with high risk of bleeding. Diabetes mellitus (DM) is associated with adverse events after cardiac procedures. We sought to compare procedural and hospital outcomes in patients who underwent LAAC with and without DM. The Nationwide Inpatient Database was queried for patients with atrial fibrillation who underwent LAAC between January 1, 2016, and December 31, 2019.
Source: The American Journal of Cardiology - July 11, 2023 Category: Cardiology Authors: Mohamed Hamed, Ramez Morcos, Ayman Elbadawi, Ahmed Osman, Hani Jneid, Wissam Khalife, Brijeshwar Maini, Houman Khalili Source Type: research
Low Utility of Short-Term Rhythm Assessment Before Long-Term Rhythm Monitoring in Patients With Cryptogenic Stroke
Implantable cardiac monitors are routinely placed for long-term monitoring (LTM) after a period of negative short-term monitoring (STM) to increase atrial fibrillation (AF) detection after a cryptogenic stroke or transient ischemic attack (TIA). Optimizing AF monitoring after a cryptogenic stroke is critical to improve outcomes and reduce costs. We sought to compare the diagnostic yield of STM versus LTM, assess the impact of routine STM on hospitalization length of stay, and perform a financial analysis comparing the current model to a theoretical model wherein patients can proceed directly to LTM.
Source: The American Journal of Cardiology - July 11, 2023 Category: Cardiology Authors: Samuel J. Apple, David Flomenbaum, Matthew Parker, Sanya Chhikara, Aaron Stolarov, Jack Moser, Sheetal Vasundara Mathai, Jiyoung Seo, Neal Ferrick, Jay J. Chudow, Luigi Di Biase, Andrew Krumerman, Kevin J. Ferrick Source Type: research
Warfarin faring better: Vitamin K antagonists beat rivaroxaban and apixaban in the INVICTUS and PROACT Xa trials
J Thromb Haemost. 2023 Jul 8:S1538-7836(23)00523-8. doi: 10.1016/j.jtha.2023.06.036. Online ahead of print.ABSTRACTAlthough guidelines give preference to the direct oral anticoagulants (DOACs) over vitamin K antagonists (VKAs) for stroke prevention in most patients with atrial fibrillation (AF), DOACs are not recommended in those with rheumatic heart disease or mechanical heart valves. The results of the INVICTUS trial (Investigation of Rheumatic AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies), which compared rivaroxaban with a VKA in patients with rheumatic heart disease associated AF, and the PR...
Source: Atherosclerosis - July 10, 2023 Category: Cardiology Authors: John W Eikelboom Jeffrey I Weitz Source Type: research
Five-year-outcome of new-onset perioperative atrial fibrillation after left atrial appendage amputation concomitant with cardiac surgery
ConclusionPOAF is associated with a higher rate of the combined endpoint of all-cause mortality, stroke and rehospitalization. The composite endpoint in patients with LAA-amputation concomitant with OPCAB surgery developing new-onset POAF in a 5-year follow-up was not increased compared to a control cohort maintaining sinus rhythm.Graphical abstractFive-year outcome of patients with POAF and LAA-amputation;95% CI, 95% confidence interval,CPR, cardiopulmonary resuscitation,ECLS, extracorporeal life support,HR, hazard ratio,IABP, intra-aortic balloon pump,LAA, left atrial appendage,OPCAB, off-pump coronary artery bypass graf...
Source: Clinical Research in Cardiology - July 10, 2023 Category: Cardiology Source Type: research
Phenotypes and outcomes in non-anticoagulated patients with atrial fibrillation: An unsupervised cluster analysis
CONCLUSION: Cluster analysis identified three statistically driven groups of patients with atrial fibrillation, with distinct phenotype characteristics and associated with different risks for major clinical adverse events.PMID:37422421 | DOI:10.1016/j.acvd.2023.06.001
Source: Archives of Cardiovascular Diseases - July 8, 2023 Category: Cardiology Authors: Arnaud Bisson Ameenathul M Fawzy Giulio Francesco Romiti Marco Proietti Denis Angoulvant Wahbi El-Bouri Gregory Y H Lip Laurent Fauchier Source Type: research
