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E-268 Large vessel occlusion stroke transfers achieve faster arrival-to-puncture times and improved outcomes with direct-to-endovascular suite protocol
ConclusionIn a hub-and-spoke telestroke network, accepting transferred patients directly to the angio-suite was associated with dramatically reduced arrival-to-puncture time and may lead to improved 90-day outcomes. Direct-to-angio-suite protocols should continue to be evaluated in other regions and telestroke models.Disclosures R. Regenhardt: None. J. Rosenthal: None. A. Dmytriw: None. J. Vranic: None. A. Bonkhoff: None. M. Bretzner: None. J. Hirsch: None. J. Rabinov: None. C. Stapleton: None. A. Patel: None. A. Singhal: None. N. Rost: None. T. Leslie-mazwi: None. M. Etherton: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Regenhardt, R., Rosenthal, J., Dmytriw, A., Vranic, J., Bonkhoff, A., Bretzner, M., Hirsch, J., Rabinov, J., Stapleton, C., Patel, A., Singhal, A., Rost, N., Leslie-mazwi, T., Etherton, M. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-023 Predictors of outcomes in tandem anterior circulation occlusions following mechanical thrombectomy
In this study, we present outcomes of patients undergoing tandem mechanical thrombectomy. We demonstrate that stenting is associated with improved final reperfusion, but increased odds of asymptomatic ICH. Additional clinical trials should be performed to optimize the procedure and improve patient outcomes.Disclosures J. Catapano: None. D. Farhadi: None. A. Naik: None. S. Koester: None. E. Winkler: None. V. Srinivasan: None. K. Karahalios: None. J. Rulney: None. S. Desai: None. A. Jadhav: None. F. Albuquerque: None. A. Ducruet: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Catapano, J., Farhadi, D., Naik, A., Koester, S., Winkler, E., Srinivasan, V., Karahalios, K., Rulney, J., Desai, S., Jadhav, A., Albuquerque, F., Ducruet, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-030 Feasibility and safety of mechanical thrombectomy for sole primary angular artery M3 and M4 MCA occlusions
ConclusionAngular artery occlusions often present with disabling symptoms, commonly including speech deficits and limb paresis. Our limited data suggests that mechanical thrombectomy of the angular artery is feasible and safe. As with thrombectomy in other vascular territories, and amongst other factors, patient outcome is influenced by grade of reperfusion.Disclosures A. Kuhn: None. J. Singh: None. F. Massari: None. A. Puri: 1; C; NIH, Microvention, Cerenovus, Medtronic Neurovascular and Stryker Neurovascular. 2; C; Medtronic Neurovascular, Stryker NeurovascularBalt, Q’Apel Medical, Cerenovus, Microvention, Imperati...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Kuhn, A., Singh, J., Massari, F., Puri, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-035 Intra-arterial tissue plasminogen activator (IA-tPA) as first line and salvage therapy to achieve complete reperfusion in acute ischemic stroke
ConclusionFor tough-to-remove clots, IA-tPA as first-line and salvage therapy can be potentially efficacious with adequate results.Disclosures M. Waqas: None. S. Housley: None. A. Baig: None. J. Cappuzzo: None. A. Monteiro: None. W. Khawar: None. E. Levy: 2; C; Claret Medical, GLG Consulting, Guidepoint Global, Imperial Care, Medtronic, Rebound, StimMed, Misionix, Mosiac, Clarion, IRRAS. 3; C; Medtronic. 4; C; NeXtGen Biologics, RAPID Medical, Claret Medical, Cognition Medical, Imperative Care, Rebound Therapeutics, StimMed, Three Rivers Medical. 6; C; Reimbursement for travel and food for some meetings with the CNS and AB...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Waqas, M., Housley, S., Baig, A., Cappuzzo, J., Monteiro, A., Khawar, W., Levy, E., Siddiqui, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-092 Use of balloon-guide catheters for concomitant mechanical thrombectomy and carotid revascularization with flow-arrest results in significantly lower sICH and better 90-day outcomes in tandem stroke patients
ConclusionUse of balloon-guide catheters for concomitant mechanical thrombectomy and carotid revascularization with flow-arrest results in significantly lower sICH and better 90-day outcomes in tandem stroke patients.Disclosures A. Baig: None. J. Neumaier: None. M. Waqas: None. A. Monteiro: None. J. Cappuzzo: None. W. Khawar: None. B. Donnelly: None. E. Levy: 2; C; : Claret Medical, GLG Consulting, Guidepoint Global, Imperial Care, Medtronic, Rebound, StimMed, Misionix, Mosiac, Clarion, IRRAS. 4; C; NeXtGen Biologics, RAPID Medical, Claret Medical, Cognition Medical, Imperative Care, Rebound Therapeutics, StimMed, Three Ri...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Baig, A., Neumaier, J., Waqas, M., Monteiro, A., Cappuzzo, J., Khawar, W., Donnelly, B., Levy, E., Siddiqui, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-119 Predictors of first pass efficacy in posterior circulation acute ischemic strokes
ConclusionFPE is a crucial predictor of successful ET in pcAIS, emphasizing the FPE and faster revascularization as role players in clinical outcomes of pcAIS. Atrial fibrillation and previous AIS independently predict FPE. The discrepancy in FPE rates by clot composition is illustrated by the higher rates of FPE in atrial fibrillation patients. Therefore, future histological and clinical studies are warranted to further address the clinical features of ischemic clots.Disclosures M. Hafeez: None. M. Essibayi: None. D. Raper: None. S. Al Kasab: None. J. Burks: None. D. Alsbrook: None. M. Park: None. T. Dumont: None. R. Town...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Hafeez, M., Essibayi, M., Raper, D., Al Kasab, S., Burks, J., Alsbrook, D., Park, M., Dumont, T., Townsend, R., Starke, R., Arthur, A., Goyal, N., Maier, I., Wolfe, S., Mascitelli, J., Fargen, K., Spiotta, A., Kan, P. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-216 Stroke thrombectomy outcomes by biological sex - a multicenter study from the star collaboration
ConclusionsOlder females with higher baseline disability are more likely to undergo mechanical thrombectomy compared to males. Biological sex is not an independent predictor of thrombectomy outcomes in acute stroke when controlling for baseline and comorbid variables. Future studies will explore the determinants underlying differences in presentations and outcomes betweenDisclosures L. Dimisko: 1; C; T32NR012715. V. Hertzberg: None. J. Grossberg: None. B. Howard: None. C. Cawley: None. F. Tong: None. P. Jabbour: 2; C; Medtronic, MicroVention, Cerus Endovascular, and Balt. I. Maier: None. S. Wolfe: None. A. Rai: None. R. St...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Dimisko, L., Hertzberg, V., Grossberg, J., Howard, B., Cawley, C., Tong, F., Jabbour, P., Maier, I., Wolfe, S., Rai, A., Starke, R., Gory, B., Psychogios, M., Shaban, A., Arthur, A., Kim, J., Yoshimura, S., Kan, P., De Leacy, R., Fragata, I., Polifka, A., Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

P-030 Mechanical thrombectomy in medium vessel occlusions using the novel aspiration MIVI Q catheters: an international multicenter experience
ConclusionsTreatment of MeVO patients with Q catheters resulted in optimal angiographic and clinical outcomes. Though angiographic results were similar between primary and secondary MeVOs, the first had less severe presentation and better outcomes at 90-days than the latter.Disclosures A. Monteiro: None. L. Makalanda: None. J. Wareham: None. J. Jones: None. P. Dhillon: None. P. Bhogal: None. W. Brinjikji: None. M. Mokin: None. A. Siddiqui: 1; C; Co-investigator for NIH – 1R01EB030092–01, Project Title: High Speed Angiography at 1000 frames per second; Mentor for Brain Aneurysm Foundation Carol W. Harvey Chair o...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Monteiro, A., Makalanda, L., Wareham, J., Jones, J., Dhillon, P., Bhogal, P., Brinjikji, W., Mokin, M., Siddiqui, A. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research

Aetiology, secondary prevention strategies and outcomes of ischaemic stroke despite oral anticoagulant therapy in patients with atrial fibrillation
Conclusions Stroke despite anticoagulation comprises heterogeneous aetiologies and cardioembolism despite sufficient anticoagulation is most common. While DOAC were associated with better outcomes than VKA, adding antiplatelets was linked to worse outcomes in these high-risk patients. Our findings indicate that individualised and novel preventive strategies beyond the currently available anticoagulants are needed. Trial registration number ISRCTN48292829.
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 27, 2022 Category: Neurosurgery Authors: Polymeris, A. A., Meinel, T. R., Oehler, H., Hölscher, K., Zietz, A., Scheitz, J. F., Nolte, C. H., Stretz, C., Yaghi, S., Stoll, S., Wang, R., Häusler, K. G., Hellwig, S., Klammer, M. G., Litmeier, S., Leon Guerrero, C. R., Moeini-Naghani Tags: Open access Cerebrovascular disease Source Type: research

032 Improving access to inpatient ambulatory cardiac monitoring for acute stroke patients during the Covid-19 pandemic
Discussion There was a significant shift in clinical practice and diagnostic access to inpatient ACM during the pandemic, resulting in a greater proportion of tests, increased identification of AF and early anticoagulation, leading to improved patient care and potentially preventing further ischaemic events. harriet jeffery@nhs.net|ABN Bursary 41
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 27, 2022 Category: Neurosurgery Authors: Jeffery, H., Sanz, E. R., Turner, D. Tags: Live Poster, 6 May SIG4: Movement Disorders Source Type: research

Analysis of microRNA signatures in ischemic stroke thrombus
Conclusions The microRNA expression pattern can provide information regarding the mechanism of stroke by reflecting the underlying pathological status of the organ from which the thrombus was derived.
Source: Journal of NeuroInterventional Surgery - April 19, 2022 Category: Neurosurgery Authors: Kim, J.-M., Byun, J.-S., Kim, J., Park, M.-S., Hong, S. A., Nam, T.-K., Choi, H. H., Hong, S., Han, S.-H., Jeong, H.-B., Park, K.-Y., Kim, H. R. Tags: Ischemic stroke Source Type: research

A simple score to predict atherosclerotic or embolic intracranial large-vessel occlusion stroke before endovascular treatment
CONCLUSIONS: The atrial fibrillation-blood pressure-clinical neurological deficit-computed tomography hyperdense sign-diabetes mellitus (ABC2D) score can be used to identify atherosclerotic or embolic etiology of patients with ILVOS who require emergency endovascular treatment.PMID:35303701 | DOI:10.3171/2022.1.JNS212924
Source: Journal of Neurosurgery - March 18, 2022 Category: Neurosurgery Authors: Geng Liao Zhenyu Zhang Tao-Hsin Tung Yuemei He Linhui Hu Xiong Zhang Hai Chen Jinbo Huang Weijie Du Chaomao Li Zhi Yang Yong Cai Hanxiang Liang Source Type: research

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