Filtered By:
Condition: Hypertension
Nutrition: Calcium

This page shows you your search results in order of relevance. This is page number 16.

Order by Relevance | Date

Total 337 results found since Jan 2013.

No effect of calcium and vitamin D intake on maternal blood pressure in a healthy pregnant population
Pregnancy causes physiological changes in blood pressure (BP). In patients without pre-existing hypertension, BP falls during the first half of pregnancy and rises from 34 weeks onwards [1]. Hypertensive disorders in pregnancy (HDP) complicate approximately 10% of pregnancies and are associated with adverse outcomes for both mother and foetus [2]. Women with a history of HDP are also at increased risk of developing hypertension in later life as well as ischaemic heart disease, stroke and renal disease [3].
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 6, 2021 Category: OBGYN Authors: Hannah Forde, Rachel K. Crowley, Malachi J. McKenna, Mark T. Kilbane, Marie Conway, Ciara M. McDonnell, Patrick J. Twomey, Fionnuala M. McAuliffe Tags: Full length article Source Type: research

Targeting TMEM16A-encoded Ca2+-activated Cl − channels: a new paradigm for antihypertensive therapy?
Hypertension is the leading risk factor for the development of heart diseases and stroke. Many hypertensive patients experience undesirable side effects to conventional antihypertensive pharmacotherapy. Cil et  al. documented the antihypertensive profile of a novel molecule, TMinh-23 (2-bromodifluoroacetylamino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid o-tolylamide), in the spontaneously hypertensive rat model of systemic hypertension. They showed that this agent reduces blood pressu re by inhibiting transmembrane member 16A–encoded calcium-activated chloride channels in vascular myocytes from resistance arteries.
Source: Kidney International - July 19, 2021 Category: Urology & Nephrology Authors: Normand Leblanc Tags: Commentary Source Type: research

Summary: International Kidney Cancer Symposium
Conclusions:  Ideal ischemia time is 20-25 minutes or less improves short and long term renal function. >25 minutes carried 5 year risk of new onset stage 4 CKD No differences on GFR for cold vs. warm ischemia times Preoperative GFR and the percent of kidney preserved was a better predictor of post op GFR.  No ischemia preserves renal function better than warm. Longer cold ischemia times were equivalent to shorter warm ischemia times. Quality and quantity of the remaining kidney is associated with ultimate renal function. Robotics in RCC Surgery Gennady Bratslavsky, MD The opening question ...
Source: Kidney Cancer Association - December 15, 2011 Category: Urology & Nephrology Source Type: news

Piezo1 initiates platelet hyperreactivity and accelerates thrombosis in hypertension
CONCLUSIONS: Our study explains the activation of mechanoreceptor Piezo1 under hypertension is the key to abnormal platelet activation and thrombosis while providing novel platelet intervention strategies to prevent thrombosis.PMID:34411418 | DOI:10.1111/jth.15504
Source: Thrombosis and Haemostasis - August 19, 2021 Category: Hematology Authors: Weiyu Zhao Zeliang Wei Guang Xin Yulong Li Jiyan Yuan Yue Ming Chengjie Ji Qiushi Sun Shiyi Li Xinchuan Chen Wei Fu Ye Zhu Hai Niu Wen Huang Source Type: research

The Current Role of Clevidipine in the Management of Hypertension
AbstractAcute hypertension, which may damage blood vessels, causes irreversible organ damage to the vasculature, central nervous system, kidney, and heart. Clevidipine, the first third-generation calcium channel antagonist approved by the Food and Drug Administration (FDA) in the past 20 years, is an ultra-short-acting calcium channel blocker that inhibits L-type calcium channels with high clearance and low distribution, can be rapidly metabolized into the corresponding inactive acid, and is rapidly hydrolyzed into inactive metabolites by esterase in arterial blood. Clevidipine is the same as nicardipine in that the main p...
Source: American Journal of Cardiovascular Drugs - September 2, 2021 Category: Cardiology Source Type: research

Calcium supplementation for prevention of primary hypertension
CONCLUSIONS: An increase in calcium intake slightly reduces both systolic and diastolic blood pressure in normotensive people, particularly in young people, suggesting a role in the prevention of hypertension. The effect across multiple prespecified subgroups and a possible dose response effect reinforce this conclusion. Even small reductions in blood pressure could have important health implications for reducing vascular disease. A 2 mmHg lower systolic blood pressure is predicted to produce about 10% lower stroke mortality and about 7% lower mortality from ischaemic heart disease. There is a great need for adequately-pow...
Source: Cochrane Database of Systematic Reviews - October 25, 2021 Category: General Medicine Authors: Gabriela Cormick Agust ín Ciapponi Mar ía Luisa Cafferata Mar ía Sol Cormick Jos é M Belizán Source Type: research

Fat-to-muscle Ratio: A New Indicator for Coronary Artery Disease in Healthy Adults
Conclusion: In this study, a high FMR was significantly associated with CAC. A large-scale prospective study on the association with FMR and cardiovascular diseases is necessary to confirm this relationship.PMID:34790047 | PMC:PMC8579285 | DOI:10.7150/ijms.62871
Source: International Journal of Medical Sciences - November 18, 2021 Category: Biomedical Science Authors: Youngmi Eun Su Nam Lee Sang-Wook Song Ha-Na Kim Se-Hong Kim Yun-Ah Lee Sung-Goo Kang Jun-Seung Rho Ki-Dong Yoo Source Type: research