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Condition: Hypertension
Countries: South Africa Health

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Total 121 results found since Jan 2013.

Registration of amiloride in South Africa: Cutting the Gordian knot.
Authors: Rayner BL, Spence JD, Bryer A, Mpe MT Abstract Amiloride is an antagonist of the renal tubular epithelial sodium channel (ENaC). As such, it is a diuretic that is both potassium and magnesium sparing. It is used for the treatment of potassium depletion and hypertension, and is the specific therapy for hypertension due to overactivity of the ENaC (Liddle syndrome and several additional genetic causes of the Liddle phenotype - low renin and low aldosterone). It is listed as a World Health Organization essential drug, but has never been registered in South Africa (SA) and can therefore only be prescribed unde...
Source: South African Medical Journal - October 24, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Significance, definition, classification and risk factors of chronic kidney disease in South Africa.
The objective of diagnosing CKD lies in its future prevention, earlydetection and proper treatment, which will prevent or delay functional deterioration.Primary hypertension (PH) occurs in 25% of South Africa (SA)'s black population and is the putative cause of stage 5 CKD in 40 - 60%of these patients. Moreover, in this group, stage 5 CKD occurs at a relatively young age (35 - 45 years) compared with other populationgroups in whom stage 5 CKD resulting from PH usually occurs between 60 and 70 years of age. In the cohort study, PH has been found in12 - 16% of black school learners (mean age 17 years) compared with 1.8 - 2% ...
Source: South African Medical Journal - August 22, 2015 Category: African Health Tags: S Afr Med J Source Type: research

A Brief Dementia Screening Test in South Africa: Results from the Health and Aging Longitudinal Study of an INDEPTH community (HAALSI) (P4.191)
Conclusions:There is a potentially protective and long-lasting impact of secondary school education on cognitive status later in life in this setting. Using a brief screening test in this relatively poor cohort of older South Africans, patterns of low cognition are similar to those in the USA and other countries.Study Supported by:The National Institute on Aging at the National Institute of Health (NIH) (1P01AG041710-01A1; 1R01AG051144–01; 3U54HG006938-03S1). F. Mateen is supported by a subgrant of P30AG024409 from the NIH for the Harvard Center for Global Demography and Aging. The Agincourt HDSS was supported by the...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mateen, F., Jennings, E., Montana, L., Wagner, R., Kahn, K., Tollman, S., Berkman, L. Tags: Behavioral and Cognitive Neurology: Neurodegenerative Disorders Source Type: research

IJERPH, Vol. 14, Pages 1523: Prevalence of Self-Reported Diagnosed Cataract and Associated Risk Factors among Elderly South Africans
e Sokhela This paper estimates the prevalence of self-reported cataract and associated risk factors among individuals aged ≥50 years in South Africa. Data from a nationally-representative cross-sectional Study on Global AGEing and Adult Health (SAGE) (N = 3646) conducted in South Africa from 2007–2008 was analyzed. The primary outcome was self-reported cataract, and exposures included socio-demographics, self-reported co-morbidities, and behavioral factors. Linearized multivariate logistic regression models were used. The weighted prevalence of self-reported diagnosed cataract was 4.4% (95%CI: 3.4–5.8). Prevalenc...
Source: International Journal of Environmental Research and Public Health - December 6, 2017 Category: Environmental Health Authors: Nancy Phaswana-Mafuya Karl Peltzer Amelia Crampin Edmund Ahame Zinhle Sokhela Tags: Article Source Type: research

Early warning system hypertension thresholds to predict adverse outcomes in pre-eclampsia: A prospective cohort study
Conclusion The CRADLE VSA, with integrated traffic light early warning system, can identify women who are hypertensive, at increased risk of severe pre-eclampsia complications and in need of escalation of care. Women who triggered a red light were at increased risk of kidney injury, magnesium sulfate use and CCU admission.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - December 16, 2017 Category: OBGYN Source Type: research

South Africa:Hypertension - the Killer Within That We're Oblivious of
[Daily Maverick] Hypertension is South Africa's biggest epidemic. But most people don't know they have high blood pressure, and few of those on treatment have their blood pressure under control - partly because the medical profession doesn't know what drugs work for Africans. Health-e reports on World Stroke Awareness Day.
Source: AllAfrica News: Health and Medicine - October 29, 2018 Category: African Health Source Type: news

Carotid intima–media thickness, but not chronic kidney disease independently associates with noncardiac arterial vascular events in South Africa
Aim: Although chronic kidney disease (CKD) as determined from estimated glomerular filtration rate (eGFR) is recommended for risk prediction by current hypertension guidelines, the equations to derive eGFR may not perform well in black Africans. We compared whether across the adult lifespan, eGFR or CKD are as closely associated with noncardiac arterial vascular events, as carotid intima–media thickness (IMT), in Africa. Methods: In 1152 black South Africans [480 with noncardiac arterial events (294 with critical lower limb ischemia, 186 with stroke) of which 37% were premature] and 672 age, sex and ethnicity-matche...
Source: Journal of Hypertension - March 1, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Kidney Source Type: research

South Africa: Salt Is Bad for You - but How It Affects Your Body Is Still Frontier Science
[The Conversation Africa] Research has shown that excess salt intake is harmful to people's health. It can lead to high blood pressure and increase the risk of heart disease and stroke.
Source: AllAfrica News: Health and Medicine - March 12, 2019 Category: African Health Source Type: news

Ethnopharmacological importance and medical applications of Myrothamnus flabellifolius Welw. (Myrothamnaceae)-A review
ConclusionIt is envisaged that the current review will add value to more scientific research on M. flabellifolius and enhance/promote the increased interest in the sustainable commercialization of M. flabellifolius herbal tea as well as lead to the validation of unverified ethnobotanical claims.Graphical abstract
Source: Journal of Ethnopharmacology - January 19, 2020 Category: Drugs & Pharmacology Source Type: research

Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease.
CONCLUSIONS: According to moderate- to high-certainty evidence, short-chain fatty acids and LCn3 have little or no effect on mortality or cardiovascular health. However, omega-3 ALA slightly reduces the risk of CVD events and arrhythmias. PMID: 33403957 [PubMed - in process]
Source: South African Medical Journal - January 7, 2021 Category: African Health Tags: S Afr Med J Source Type: research

South Africa: How Changing Blood Pressure Targets Could Save Costs and Lives
[The Conversation Africa] High blood pressure, also known as hypertension, is a serious public health threat globally. If uncontrolled it substantially increases the risk of disability and death from stroke, heart attacks and other cardiovascular conditions. It's also a huge problem in South Africa - an estimated 35% of people in the country older than 15 have high blood pressure. This is expected to increase as the country's population rapidly ages over the coming decades.
Source: AllAfrica News: Health and Medicine - February 8, 2021 Category: African Health Source Type: news

Incidence of Cognitive Impairment during Aging in Rural South Africa: Evidence from HAALSI, 2014 to 2019
Conclusions: This study presents some of the first incidence rate estimates for aging-related cognitive impairment in rural South Africa. Social disparities in incident cognitive impairment rates were apparent in patterns similar to those observed in many high-income countries.Neuroepidemiology
Source: Neuroepidemiology - March 3, 2021 Category: Epidemiology Source Type: research

Economic growth as an underlying probable systemic driver for childhood obesity in South Africa: A Joinpoint regression and ecological analysis over 10 years
CONCLUSIONS: An increase in childhood and adolescent obesity over time was observed, while trend associations between obesity and EGIs exist.PMID:33944743 | DOI:10.7196/SAMJ.2021.v111i3.14669
Source: South African Medical Journal - May 4, 2021 Category: African Health Authors: P T Pisa N M Pisa P Chikandiwa A Chikandiwa Source Type: research