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Condition: Hypertension
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Total 229 results found since Jan 2013.

Role of Nonsteroidal Antiinflammatory Drugs in the Association Between Osteoarthritis and Cardiovascular Diseases: A Longitudinal Study
ConclusionThe findings of this first study to evaluate the mediating role of NSAIDs in the relationship between OA and CVD suggest that NSAID use contributes substantially to the OA –CVD association.
Source: Arthritis and Rheumatology - September 4, 2019 Category: Rheumatology Authors: Mohammad Atiquzzaman, Mohammad E. Karim, Jacek Kopec, Hubert Wong, Aslam H. Anis Tags: Original Article Source Type: research

Hypertension Canada ’s 2017 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults
Publication date: Available online 10 March 2017 Source:Canadian Journal of Cardiology Author(s): Alexander A. Leung, Stella S. Daskalopoulou, Kaberi Dasgupta, Kerry McBrien, Sonia Butalia, Kelly B. Zarnke, Kara Nerenberg, Kevin C. Harris, Meranda Nakhla, Lyne Cloutier, Mark Gelfer, Maxime Lamarre-Cliche, Alain Milot, Peter Bolli, Guy Tremblay, Donna McLean, Sheldon W. Tobe, Marcel Ruzicka, Kevin D. Burns, Michel Vallée, G. V. Ramesh Prasad, Steven E. Gryn, Ross D. Feldman, Peter Selby, Andrew Pipe CM, Ernesto L. Schiffrin, Philip A. McFarlane, Paul Oh, Robert A. Hegele, Milan Khara, Thomas W. Wilson, S. Brian Penner, El...
Source: Canadian Journal of Cardiology - March 9, 2017 Category: Cardiology Source Type: research

Benefits of artificial sweeteners unclear
Conclusion The study authors suggest artificial sweeteners may not aid weight loss, despite marketing claims to the contrary, and could actually increase the risk of type 2 diabetes. However, the results need to be treated with caution, as this review had numerous limitations: The randomised controlled trials had great variability and few participants, increasing the possibility of the results occurring by chance. They were also judged to be at a high risk of bias – for example, the participants could not be blinded to the intervention, and adherence (drop-out) rates were not provided. We do not know whether there w...
Source: NHS News Feed - July 19, 2017 Category: Consumer Health News Tags: Food/diet Obesity Source Type: news

Mechanisms, Clinical Significance and Prevention of Cognitive Impairment in Atrial Fibrillation
Publication date: Available online 6 October 2017 Source:Canadian Journal of Cardiology Author(s): Lena Rivard, Paul Khairy Atrial fibrillation (AF) and dementia are major health issues, with growing evidence suggesting a consistent association between AF and all forms of dementia. Although dementia and AF share several risk factors, the association appears to be independent of a history of clinical stroke and other comorbidities such as hypertension, heart failure, and diabetes. Proposed mechanisms linking AF to cognitive decline include altered hemodynamics resulting in cerebral hypoperfusion, inflammation, genetic fact...
Source: Canadian Journal of Cardiology - October 7, 2017 Category: Cardiology Source Type: research

Vascular plugging for the enlarging pulmonary arteriovenous malformation in a patient with idiopathic pulmonary artery hypertension
Publication date: Available online 2 March 2018 Source:Canadian Journal of Cardiology Author(s): Kae-Woei Liang, Chi-Yao Huang, Sheng-Ling Jan, Kuo-Yang Wang The coexistence of idiopathic pulmonary artery hypertension (IPAH) with pulmonary arteriovenous malformation (PAVM) is challenging because while the PAVM causes hypoxia and polycythemia with potential thrombotic complications, closing the PAVM increases pulmonary-artery pressure. Here, we report on a lady with PAVM and IPAH who, within two years of diagnosis, had an ischemic stroke, PAVM enlargement from 20x20x30 mm to 30x40x40 mm and oximetry decrease to 90%. Trans-...
Source: Canadian Journal of Cardiology - March 2, 2018 Category: Cardiology Source Type: research

Invasive Hemodynamics and Rejection Rates in Patients With Cardiac Sarcoidosis After Heart Transplantation
ConclusionsPatients with CS have similar post-transplant hemodynamics as patients without CS, without evidence of right ventricular dysfunction or pulmonary hypertension. Neither significant rejection nor recurrence of sarcoid in the allograft was observed in this cohort of patients with CS. Survival is similar between patients with CS and those without CS. Heart transplant is a viable strategy in selected patients with CS with excellent outcomes.RésuméIntroductionLa transplantation cardiaque orthotopique (TCO) est de plus en plus utilisée lors d’insuffisance cardiaque terminale liée à une sarcoïdose cardiaque (SC)...
Source: Canadian Journal of Cardiology - July 24, 2018 Category: Cardiology Source Type: research

Effects of Riociguat on Right Ventricular Remodelling in Chronic Thromboembolic Pulmonary Hypertension Patients: A Prospective Study
ConclusionsRiociguat treatment was associated with increased RV stroke volume index and trends for improvement in myocardial remodelling in patients with CTEPH. A larger clinical study is warranted to observe the therapeutic benefits of riociguat on RV remodelling.RésuméContexteLes effets du traitement par le riociguat sur le métabolisme, la perfusion et le débit du ventricule droit (VD) chez les patients atteints d’hypertension pulmonaire thromboembolique chronique (HPTC) sont inconnus. Dans la présente étude, nous analysons les changements aux ventriculaires droits associés au traitement par le riociguat.Méthod...
Source: Canadian Journal of Cardiology - August 29, 2018 Category: Cardiology Source Type: research

Prothrombotic state in atrial fibrillation patients with 1 additional risk factor of the CHA2DS2-VASc score (beyond sex)
ConclusionsA prothrombotic state (increased thrombin generation, denser fibrin clots, impaired fibrinolysis, and endothelial injury) characterizes AF patients with one additional clinical stroke risk factor (beyond sex), with age 65-74 years being particularly associated with a prothrombotic indices.
Source: Canadian Journal of Cardiology - January 30, 2019 Category: Cardiology Source Type: research

Peridevice Leak After Left Atrial Appendage Closure: Incidence, Risk Factors, and Clinical Impact
ConclusionsThe PDL rate detected by CCTA after LAAC was high, especially in cases with a low device compression ratio (< 10%), but decreased over time. The incidence of MACE was quantitatively greater with PDL, but the difference was not statistically significant. Larger studies are needed to determine the clinical importance of PDL.RésuméIntroductionPeu d’études ont fait état des taux et des répercussions cliniques des fuites périprothétiques (FPP) après la fermeture de l’appendice auriculaire gauche (AAG) par voie percutanée.MéthodesNous avons inscrit de manière prospective tous les patients consécuti...
Source: Canadian Journal of Cardiology - March 30, 2019 Category: Cardiology Source Type: research

Decompressive Craniectomy for Traumatic Brain Injury: Postoperative Cerebral Hemodynamic Evaluation
Conclusion: There is a wide heterogeneity of postoperative cerebral hemodynamic findings among TBI patients who underwent DC, including hemodynamic heterogeneity between their cerebral hemispheres. DC was proved to be effective for the treatment of cerebral oligoemia. Our data support the concept of heterogeneous nature of the pathophysiology of the TBI and suggest that DC as the sole treatment modality is insufficient. Introduction Decompressive craniectomy (DC) may effectively decrease intracranial pressure (ICP) and increase cerebral perfusion pressure (CPP) in traumatic brain injury (TBI) patients with refracto...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Decompressive Craniectomy for Traumatic Brain Injury: Postoperative TCD Cerebral Hemodynamic Evaluation
Conclusion: There is a wide heterogeneity of postoperative cerebral hemodynamic findings among TBI patients who underwent DC, including hemodynamic heterogeneity between their cerebral hemispheres. DC was proved to be effective for the treatment of cerebral oligoemia. Our data support the concept of heterogeneous nature of the pathophysiology of the TBI and suggest that DC as the sole treatment modality is insufficient. Introduction Decompressive craniectomy (DC) may effectively decrease intracranial pressure (ICP) and increase cerebral perfusion pressure (CPP) in traumatic brain injury (TBI) patients with refracto...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Mortality and cardiovascular and respiratory morbidity in individuals with impaired FEV1 (PURE): an international, community-based cohort study
Publication date: May 2019Source: The Lancet Global Health, Volume 7, Issue 5Author(s): MyLinh Duong, Shofiqul Islam, Sumathy Rangarajan, Darryl Leong, Om Kurmi, Koon Teo, Kieran Killian, Gilles Dagenais, Scott Lear, Andreas Wielgosz, Sanjeev Nair, Viswanathan Mohan, Prem Mony, Rajeev Gupta, Rajesh Kumar, Omar Rahman, Khalid Yusoff, Johannes Lodewykus du Plessis, Ehimario U Igumbor, Jephat ChifambaSummaryBackgroundThe associations between the extent of forced expiratory volume in 1 s (FEV1) impairment and mortality, incident cardiovascular disease, and respiratory hospitalisations are unclear, and how these associations mi...
Source: The Lancet Global Health - April 17, 2019 Category: International Medicine & Public Health Source Type: research

Perioperative Atrial Fibrillation in Non-Cardiac Surgeries for Malignancies and One-Year Recurrence
ConclusionsAF recurs in approximately thirty percent of POAF patients with malignancy in the subsequent year; most recurrences are asymptomatic.
Source: Canadian Journal of Cardiology - July 12, 2019 Category: Cardiology Source Type: research

Perioperative Atrial Fibrillation in Noncardiac Surgeries for Malignancies and One-Year Recurrence
ConclusionsAF recurs in approximately 30% of patients with POAF with malignancy in the subsequent year; most recurrences are asymptomatic.RésuméContexteIl arrive fréquemment qu’un patient subissant une intervention chirurgicale non cardiaque présente une fibrillation auriculaire périopératoire (FAPO). On ne sait toutefois pas si d’autres épisodes de fibrillation auriculaire (FA) surviennent par la suite.MéthodologieLes auteurs ont mené une étude d’observation prospective unicentrique auprès de patients ayant subi une intervention chirurgicale non cardiaque visant à retirer une tumeur. Les patients ont fai...
Source: Canadian Journal of Cardiology - November 2, 2019 Category: Cardiology Source Type: research

Variation in bleeding risk estimates among online calculators: Cross-sectional study of apps used by and for patients with atrial fibrillation
CONCLUSION: Inconsistencies and a lack of precision were observed in annual risk estimates and risk stratification produced by Web and mobile bleeding risk calculators for patients with atrial fibrillation. Clinicians should refer to annual bleeding risks observed in major randomized controlled trials to inform risk estimates communicated to patients.PMID:35418403 | DOI:10.46747/cfp.6804e127
Source: Canadian Family Physician Medecin de Famille Canadien - April 14, 2022 Category: Primary Care Authors: Ryan Pelletier Jeff Nagge John-Michael Gamble Source Type: research