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The Beyond Ageing Project Phase 2 - a double-blind, selective prevention, randomised, placebo-controlled trial of omega-3 fatty acids and sertraline in an older age cohort at risk for depression: study protocol for a randomized controlled trial
DiscussionThe current health, social and economic costs of late-life depression make prevention imperative from a public health perspective. This innovative trial aims to address the long-neglected area of prevention of depression in older adults. The interventions are targeted to the pathophysiology of disease, and regardless of the effect size of treatment, the outcomes will offer major scientific advances regarding the neurobiological action of these agents. The main results are expected to be available in 2017.Trial RegistrationAustralian and New Zealand Clinical Trials Registry ACTRN12610000032055 (12 January 2010)
Source: BioMed Central - June 2, 2015 Category: Journals (General) Authors: Nicole CockayneShantel DuffyRosalind BonomallyAmelia EnglishPaul AmmingerAndrew MackinnonHelen ChristensenSharon NaismithIan Hickie Source Type: research
Mortality and comorbidities in patients with multiple sclerosis compared with a population without multiple sclerosis: An observational study using the US department of defense administrative claims database
Conclusions Rates of mortality and several comorbidities are higher in the MS versus non-MS cohort. Early recognition and management of comorbidities may reduce premature mortality and improve quality of life in patients with MS.
Source: Multiple Sclerosis and Related Disorders - August 19, 2015 Category: Neurology Source Type: research
Treatment of status migrainosus by general anesthesia: a case report
Conclusion Status migrainosus is a rare disabling complication and anesthetics have been the subject of research in its treatment; the option for general anesthesia with agents that stimulate GABA receptors, propofol and isoflurane, in association with fentanyl, proved effective and should encourage new research.
Source: Brazilian Journal of Anesthesiology - August 29, 2015 Category: Anesthesiology Source Type: research
Doping with anabolic androgenic steroids (AAS): Adverse effects on non-reproductive organs and functions
Abstract
Since the 1970s anabolic androgenic steroids (AAS) have been abused at ever increasing rates in competitive athletics, in recreational sports and in bodybuilding. Exceedingly high doses are often consumed over long periods, in particular by bodybuilders, causing acute or chronic adverse side effects frequently complicated by additional polypharmacy. This review summarizes side effects on non-reproductive organs and functions; effects on male and female reproduction have been recently reviewed in a parallel paper. Among the most striking AAS side effects are increases in haematocrit and coagulation causing...
Source: Reviews in Endocrine and Metabolic Disorders - September 15, 2015 Category: Endocrinology Source Type: research
Doping with anabolic androgenic steroids (AAS): Adverse effects on non-reproductive organs and functions.
Abstract
Since the 1970s anabolic androgenic steroids (AAS) have been abused at ever increasing rates in competitive athletics, in recreational sports and in bodybuilding. Exceedingly high doses are often consumed over long periods, in particular by bodybuilders, causing acute or chronic adverse side effects frequently complicated by additional polypharmacy. This review summarizes side effects on non-reproductive organs and functions; effects on male and female reproduction have been recently reviewed in a parallel paper. Among the most striking AAS side effects are increases in haematocrit and coagulation causing...
Source: ENDOCR REV - September 15, 2015 Category: Endocrinology Authors: Nieschlag E, Vorona E Tags: Rev Endocr Metab Disord Source Type: research
The health status of adults on the autism spectrum
The objective of this study was to describe the frequency of psychiatric and medical conditions among a large, diverse, insured population of adults with autism in the United States. Participants were adult members of Kaiser Permanente Northern California enrolled from 2008 to 2012. Autism spectrum disorder cases (N = 1507) were adults with autism spectrum disorder diagnoses (International Classification of Diseases-9-Clinical Modification codes 299.0, 299.8, 299.9) recorded in medical records on at least two separate occasions. Controls (N = 15,070) were adults without any autism spectrum disorder diagnoses sampled at a 1...
Source: Autism - September 22, 2015 Category: Neurology Authors: Croen, L. A., Zerbo, O., Qian, Y., Massolo, M. L., Rich, S., Sidney, S., Kripke, C. Tags: Special Issue Articles Source Type: research
Design Your Healthy and Happy Life With 3 Quick Makeovers: Small Steps Equal a Big Impact
Design your healthy and happy life with these super quick makeover tips that will have you wanting more. A healthy and happy life is about living blissfully, with passion and purpose, not just about the absence of disease. The great news is that we can design our own healthy lifestyle plan just like interior designers create beautiful spaces; we can design it no matter where we are in your own health journey; dealing with an illness, or recovering from an injury. What's even better news is that we don't need to do a complete overhaul. Who doesn't love a quick makeover? Sometimes, all it takes is new throw pillows or a bold...
Source: Healthy Living - The Huffington Post - September 29, 2015 Category: Consumer Health News Source Type: news
The Man Who Grew Eyes
The train line from mainland Kobe is a marvel of urban transportation. Opened in 1981, Japan’s first driverless, fully automated train pulls out of Sannomiya station, guided smoothly along elevated tracks that stand precariously over the bustling city streets below, across the bay to the Port Island. The island, and much of the city, was razed to the ground in the Great Hanshin Earthquake of 1995 – which killed more than 5,000 people and destroyed more than 100,000 of Kobe’s buildings – and built anew in subsequent years. As the train proceeds, the landscape fills with skyscrapers. The Rokkō mounta...
Source: Healthy Living - The Huffington Post - October 11, 2015 Category: Consumer Health News Source Type: news
All-Cause and Cause-Specific Mortality Associated with Bariatric Surgery: A Review
Abstract
The question of whether or not nonsurgical intentional or voluntary weight loss results in reduced mortality has been equivocal, with long-term mortality following weight loss being reported as increased, decreased, and not changed. In part, inconsistent results have been attributed to the uncertainty of whether the intentionality of weight loss is accurately reported in large population studies and also that achieving significant and sustained voluntary weight loss in large intervention trials is extremely difficult. Bariatric surgery has generally been free of these conflicts. Patients voluntarily unde...
Source: Current Atherosclerosis Reports - October 26, 2015 Category: Cardiology Source Type: research
How mindfulness gave a boy peace and confidence
James Doty’s prospects were bleak, but then one summer he was taught a new, compassionate way to thinkWhen I speak in my capacity as a professor of neurosurgery at Stanford University or as an entrepreneur with a company worth $1.3bn, there is an assumption that I had a privileged background, one of affluence. In fact I grew up in poverty on public assistance with an alcoholic father and a mother impaired by a stroke who was chronically depressed and attempted suicide many times. My father was jailed repeatedly and we were evicted from our home on quite a few occasions. Related: Why babies are so good with wookiees Continue reading...
Source: Guardian Unlimited Science - December 6, 2015 Category: Science Authors: James Doty Tags: Mindfulness Neuroscience Child rights Life and style Psychology Source Type: news
Shortcut to Better Brain Power
Natural caffeine is one of the oldest stimulants in the world. And it’s loaded with health benefits.
It can enhance your mental clarity and focus, and it’s a potent antioxidant… as long as you take it in moderation and it comes from natural sources.
But the problem with most energy drinks these days is the caffeine itself. It’s unnatural and synthetic.
We’ve known for a long time that the antioxidant power of caffeine cuts the risk of dying from heart disease or developing Alzheimer’s.
But now a study from the Department of Nutrition at the Harvard School of Public Health, researchers looked at 30 years of data...
Source: Al Sears, MD Natural Remedies - December 15, 2015 Category: Complementary Medicine Authors: Al Sears Tags: Brain Health caffeine coffee guarana Source Type: news
The idea you can be fat but fit is 'a myth' study argues
ConclusionThis was a large prospective cohort study from Sweden, which was carried out in young adult males who were then followed for a period of around 29 years. The study found that lower levels of aerobic fitness were associated with risk of early death, but that this risk of death was greater for those with a high BMI, even if they had a high level of aerobic fitness. This study has a number of strengths and limitations. The limitations are that a large number of participants had missing smoking data and therefore it was not possible to control for the confounding effect of smoking. The lower fitness level group with...
Source: NHS News Feed - December 21, 2015 Category: Consumer Health News Tags: Food/diet Obesity Source Type: news
How Terrified Should We Be?
After every terrorist attack we go through a period of overwhelming fear that we will individually be the target of terrorism. Recently a man told me that he will avoid going to crowded areas of the city because he fears being killed by a terrorist. A woman fears flying because she fears the plane will be blown up by a terrorist. Years ago, after 9/11, a woman told me that she feared "Arab-looking men" in the subway. And, after 9/11, years ago, a family moved to Colorado from New York City because of their fear of terrorism. Fear pervaded the lives of many people and, once again, after the attack in San Bernardino, Califor...
Source: Healthy Living - The Huffington Post - December 23, 2015 Category: Consumer Health News Source Type: news
Depression in the Elderly: A Common Condition That's Often Overlooked
When Suzette Santos, RN, a behavioral health nurse with the Visiting Nurse Service of New York (VNSNY), was assigned to the case of Grace*, an 89-year-old resident of Nassau County on Long Island, she had some idea what to expect. Suzette had cared for Grace a year earlier, as the elderly woman struggled to cope with depression brought on by the recent loss of her husband and lifelong partner. When Suzette reconnected with her patient this time, she could immediately see that Grace's depression had gotten worse. "She had lost a lot of weight -- about 20 pounds," Suzette recalls. "She had no interest in cooking or eating, ...
Source: Healthy Living - The Huffington Post - December 23, 2015 Category: Consumer Health News Source Type: news
