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Atrial Myopathy and Ischemic Stroke in Heart Failure With Preserved Ejection Fraction
We examined the hypothesis that atrial myopathy may be associated with ischemic stroke in patients with heart failure with preserved ejection fraction. This is an exploratory, post hoc analysis of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial. Patients with sinus rhythm documented at baseline electrocardiogram and without known AF were included in this analysis.
Source: The American Journal of Cardiology - July 27, 2023 Category: Cardiology Authors: Kassem Farhat, Khaled Elkholey, Zain Ul Abideen Asad, Stavros Stavrakis Source Type: research

Half-Dose Tenecteplase or Primary Percutaneous Coronary Intervention in Older Patients With ST-Segment-Elevation Myocardial Infarction in STREAM-2: A Randomized, Open-Label Trial
CONCLUSIONS: Halving the dose of tenecteplase in a pharmaco-invasive strategy in this early-presenting, older STEMI population was associated with electrocardiographic changes that were at least comparable to those after primary PCI. Similar clinical efficacy and angiographic end points occurred in both treatment groups. The risk of intracranial hemorrhage was higher with half-dose tenecteplase than with primary PCI. If timely PCI is unavailable, this pharmaco-invasive strategy is a reasonable alternative, provided that contraindications to fibrinolysis are observed and excess anticoagulation is avoided.REGISTRATION: URL: ...
Source: Circulation - July 13, 2023 Category: Cardiology Authors: Frans Van de Werf Arsen D Risti ć Oleg V Averkov Alexandra AriasMendoza Yves Lambert Jos é F Kerr Saraiva Pablo Sepulveda Fernando Rosell-Ortiz John K French Ljilja B Musi ć Katleen Vandenberghe Kris Bogaerts Cynthia M Westerhout Alain Pag ès Thierry Source Type: research

Antithrombotiques oraux et pronostic apr ès un an des patients atteints de fibrillation auriculaire dans un milieu à ressources limitées
CONCLUSION: Half of patients with atrial fibrillation in this registry developed an outcome after one year of follow-up, with heart failure, new onset and paroxystic atrial fibrillation being the main predicting factors. Diagnosing and managing atrial fibrillation in patients with heart disease should therefore be considered as a key priority.PMID:37331159 | DOI:10.1016/j.ancard.2023.101616
Source: Annales de Cardiologie et d'Angeiologie - June 18, 2023 Category: Cardiology Authors: Anastase Dzudie Ines Kwawa Irene Magha Sidick Mouliom Annick Melanie Magnerou Daniel Gams Massi Blaise Barche Jules Ndjebet Manuella Magne Fotsing Viche Lade Armel Djomou Marie Solange Ndom Martin Hongieh Abanda Domin Sone Majunda Ekaney Niba Juste Ongeh Source Type: research

Clinical Efficacy and Safety of Early Intravenous Administration of Beta-Blockers in Patients Suffering from Acute ST-Segment Elevation Myocardial Infarction Without Heart Failure Undergoing Primary Percutaneous Coronary Intervention: A Study-Level Meta-Analysis of Randomized Clinical Trials
ConclusionIntravenous beta-blockers improved the MSI, decreased the risk of VT/VF in the first 24 h, and were associated with increased LVEF at 1 week and 6 months following PCI. In particular, intravenous beta-blockers started before PCI is beneficial for patients with LAD lesions.
Source: Cardiovascular Drugs and Therapy - April 1, 2023 Category: Cardiology Source Type: research

Multi-modal fusion model for predicting adverse cardiovascular outcome post percutaneous coronary intervention
Conclusion. To the best of our knowledge, this is the first study that developed a deep learning model with joint fusion architecture for the prediction of post-PCI prognosis and outperformed machine learning models developed using traditional single-source features (clinical variables or E CG features). Adding ECG data with clinical variables did not improve prediction of all-cause mortality as may be expected, but the improved performance of related cardiac outcomes shows that the fusion of ECG generates additional value.
Source: Physiological Measurement - December 22, 2022 Category: Physiology Authors: Amartya Bhattacharya, Sudarsan Sadasivuni, Chieh-Ju Chao, Pradyumna Agasthi, Chadi Ayoub, David R Holmes, Reza Arsanjani, Arindam Sanyal and Imon Banerjee Source Type: research

P ‐wave durations from automated electrocardiogram analysis to predict atrial fibrillation and mortality in heart failure
ConclusionsExtreme values of maximum P-wave durations ( ≤90 ms and ≥141 ms) were significant predictors of new-onset AF, cardiovascular mortality, and all-cause mortality.
Source: ESC Heart Failure - December 3, 2022 Category: Cardiology Authors: Jiandong Zhou, Andrew Li, Martin Tan, Matthew Chung Yan Lam, Lok Tin Hung, Ronald Wing Hei Siu, Sharen Lee, Ishan Lakhani, Jeffrey Shi Kai Chan, Khalid Bin Waleed, Tong Liu, Kamalan Jeevaratnam, Qingpeng Zhang, Gary Tse Tags: Original Article Source Type: research

Identification of magnetic resonance imaging features for the prediction of unrecognized atrial fibrillation in acute ischemic stroke
Conclusion Initial MRI at the time of stroke may be useful to predict which patients have cardioembolic stroke caused by unrecognized AF. Further studies are warranted to verify these findings and their application to high-risk patients.
Source: Frontiers in Neurology - September 13, 2022 Category: Neurology Source Type: research

Usefulness of Triglyceride-glucose index for detecting prevalent atrial fibrillation in a type 2 diabetic population
CONCLUSION: Our data supported a linear and robust correlation between TyG and the prevalent AF in a diabetic population. Moreover, our results implicated the potential usefulness of TyG to refine the detection of prevalent AF in a diabetic population.PMID:36093727 | DOI:10.1080/00325481.2022.2124088
Source: Postgraduate Medicine - September 12, 2022 Category: Internal Medicine Authors: Wenrui Shi Mu Qin Shaohui Wu Kai Xu Qidong Zheng Xu Liu Source Type: research

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