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Total 226 results found since Jan 2013.

Use of Nonsteroidal Anti-Inflammatory Drugs and Risk of Chronic Kidney Disease in Subjects With Hypertension: Nationwide Longitudinal Cohort Study Kidney
Limited studies have examined the effects of nonsteroidal anti-inflammatory drug (NSAID) use on the risk of chronic kidney disease (CKD), especially in subjects with hypertension. Using National Health Insurance claims data in Taiwan, we conducted a propensity score–matched cohort study to investigate the relationship between NSAID use and CKD in subjects with hypertension. A total of 31976 subjects were included in this study: subjects not taking any NSAIDs in 2007 (n=10782); subjects taking NSAIDs for 1 to 89 days in 2007 (n=10605); and subjects taking NSAIDs for ≥90 days in 2007 (n=10589). We performed multivar...
Source: Hypertension - August 12, 2015 Category: Cardiology Authors: Hsu, C.-C., Wang, H., Hsu, Y.-H., Chuang, S.-Y., Huang, Y.-W., Chang, Y.-K., Liu, J.-S., Hsiung, C. A., Tsai, H.-J. Tags: Clinical Studies Kidney Source Type: research

Hemodialysis with end-stage renal disease did not raise the risk of intracranial hemorrhage after a head injury
Conclusions: HD +ESRD did not increase the post-HI risk of ICH. Therefore, it may not be necessary to lower the threshold of head CT in HD +ESRD patients.
Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine - October 28, 2015 Category: Emergency Medicine Authors: Hsin-Hung ChenChien-Chin HsuShih-Feng WengHung-Jung LinJhi-Joung WangHow-Ran GuoShih-Bin SuChien-Cheng HuangJiann-Hwa Chen Source Type: research

Comparative Effectiveness of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers in Terms of Major Cardiovascular Disease Outcomes in Elderly Patients: A Nationwide Population-Based Cohort Study
Abstract: Renin and aldosterone activity levels are low in elderly patients, raising concerns about the benefits and risks of angiotensin-converting-enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARB) use. However, data from direct comparisons of the effects of ACEIs on ARBs in the elderly population remain inconclusive. In this nationwide study, all patients aged ≥ 70 years were retrieved from the Taiwan National Health Insurance database for the period 2000 to 2009 and were followed up until the end of 2010. The ARB cohort (12,347 patients who continuously used ARBs for ≥ 90 days) was matched to ...
Source: Medicine - October 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Risk of Peripheral Arterial Occlusive Disease in Patients With Systemic Lupus Erythematosus: A Nationwide Population-Based Cohort Study
Abstract: Systemic lupus erythematosus (SLE) is associated with atherosclerosis, but the relationship between SLE and peripheral arterial occlusive disease (PAOD) remains unclear. We sought to investigate this relationship by comparing cardiovascular complications in patients with and without SLE. Data on patients from 2000 to 2011 were collected from the National Health Insurance Research Database of Taiwan. The SLE cohort was frequency-matched according to age, sex, and history of diabetes mellitus (DM) with patients without SLE (control cohort). We evaluated the risk of cardiovascular complications, including hypertensi...
Source: Medicine - November 1, 2015 Category: Internal Medicine Tags: Observational Study Source Type: research

Relation Between Hepatitis C Virus Exposure and Risk of Osteoporosis: A Nationwide Population-Based Study
Abstract: The effect of hepatitis C virus (HCV) exposure on bone mineral density without advanced liver disease remains debated. Thus, we assessed the relation between HCV exposure and the risk of osteoporosis. From 2000 to 2011, patients aged>20 years with HCV exposure were identified from the Longitudinal Health Insurance Database 2000. Of the 51,535 sampled patients, 41,228 and 10,307 patients were categorized as the comparison and the HCV exposure cohorts, respectively. The overall incidence of osteoporosis in the HCV exposure cohort was higher than in the comparison cohort (8.27 vs 6.19 per 1000 person-years; crude ha...
Source: Medicine - November 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

The association between participation in a pay-for-performance program and macrovascular complications in patients with type 2 diabetes in Taiwan: A nationwide population-based cohort study
Conclusions Compared with patients not enrolled in the P4P program, P4P patients had lower risk of developing serious vascular complications. Our empirical findings provide evidence for the potential long-term benefit of P4P programs in reducing risks of macrovascular complications.
Source: Preventive Medicine - January 11, 2016 Category: Global & Universal Source Type: research

Health status of populations living in French overseas territories in 2012, compared with metropolitan France: An analysis of the national health insurance database.
CONCLUSION: This study highlights the utility of administrative database to compare and follow population health status considering healthcare use. Specific Public Health policies are justified for FOT, taking into account the specific context of each FOT, the necessity of prevention initiatives and screening to reduce the frequency of the chronic diseases. PMID: 27238162 [PubMed - as supplied by publisher]
Source: Revue d Epidemiologie et de Sante Publique - May 31, 2016 Category: Epidemiology Tags: Rev Epidemiol Sante Publique Source Type: research

Incidence and Risk Factors for Atrial Fibrillation in Korea: the National Health Insurance Service Database (2002-2010).
CONCLUSION: Incidence of AF increased with age and was higher in men than in women. A larger proportion of AF events was attributable to hypertension than to other co-morbidities. PMID: 27482260 [PubMed]
Source: Korean Circulation Journal - August 4, 2016 Category: Cardiology Tags: Korean Circ J Source Type: research

Usefulness of HATCH score in the prediction of new-onset atrial fibrillation for Asians
Abstract: The HATCH score (hypertension , age>75 years , stroke or transient ischemic attack , chronic obstructive pulmonary disease , and heart failure ) was reported to be useful for predicting the progression of atrial fibrillation (AF) from paroxysmal to persistent or permanent AF for patients who participated in the Euro Heart Survey. The goal of the current study was to investigate whether the HATCH score was a useful scheme in predicting new-onset AF. Furthermore, we aimed to use the HATCH scoring system to estimate the individual risk in developing AF for patients with different comorbidities. We used the “Taiwan...
Source: Medicine - January 1, 2017 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Frequency of Early Predialysis Nephrology Care and  Postdialysis Cardiovascular Events
Conclusions Early frequent nephrology care for 6 or more months before the initiation of long-term dialysis therapy may improve 1-year postdialysis major cardiovascular outcomes.
Source: American Journal of Kidney Diseases - March 3, 2017 Category: Urology & Nephrology Source Type: research

Hypothyroidism is associated with all ‐cause mortality in a national cohort of chronic hemodialysis patients
ConclusionHypothyroidism is associated with increased all‐cause mortality in chronic HD patients. The interaction of hypothyroidism and diabetes, but not other common comorbidities in HD patients, has an effect on mortality risks.
Source: Nephrology - March 28, 2017 Category: Urology & Nephrology Authors: Hsuan ‐Jen Lin, Chung‐Chih Lin, Hsuan Ming Lin, Hsuan‐Ju Chen, Che‐Chen Lin, Chiz‐Tzung Chang, Che‐Yi Chou, Chiu‐Ching Huang Tags: Original Article Source Type: research

The effectiveness and safety of angiotensin-converting enzyme inhibition or receptor blockade in vascular diseases in patients with hemodialysis
Abstract: Patients with end-stage renal disease (ESRD) who are on hemodialysis have high risk of vascular diseases. Our study sought to examine whether angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin type 1 receptor blockers (ARBs) could reduce the frequencies of cardiovascular and cerebrovascular events in patients receiving hemodialysis using the medication possession ratio (MPR) method of analysis. This retrospective cohort study identified cases of ESRD with dialysis from the National Health Insurance Research Database between 1999 and 2006, and used Cox-regression methods to evaluate risk of poor outc...
Source: Medicine - March 1, 2017 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Abstract 137: Clinical Outcomes After Cardiac Stress Testing Among U.S. Patients Younger Than 65, 2006-2012 Session Title: Poster Session I
Conclusion: The percentage of commercially insured U.S. patients who had an AMI or revascularization event within 1 year of stress testing was small. In the lowest risk quintile, the a priori prevalence of coronary disease risk factors was low, and the rates of subsequent AMI and revascularization was extremely low, raising questions about the value of stress testing in this subgroup.
Source: Circulation: Cardiovascular Quality and Outcomes - March 31, 2017 Category: Cardiology Authors: Kini, V., Dayoub, E., Marzec, L., Dickinson, M., Wynia, M., Masoudi, F., Ho, M., Groeneveld, P. Tags: Session Title: Poster Session I Source Type: research

Risk of Cardiovascular and Cerebrovascular Events in COPD Patients Treated With Long-Acting β2-Agonist Combined With a Long-Acting Muscarinic or Inhaled Corticosteroid.
CONCLUSIONS: Despite concerns about the CCV effects of LAMA and LABA monotherapy, the LABA/LAMA combination had similar or lower risk of these events in comparison to LABA/ICS. Further studies are recommended to confirm these findings. PMID: 28677404 [PubMed - as supplied by publisher]
Source: The Annals of Pharmacotherapy - July 1, 2017 Category: Drugs & Pharmacology Authors: Samp JC, Joo MJ, Schumock GT, Calip GS, Pickard AS, Lee TA Tags: Ann Pharmacother Source Type: research

Abstract P173: Target Blood Pressure in Elderly Hypertensive Patients: A Korean National Health Insurance Service Health Examinee Cohort Study Session Title: Onsite Poster Competition I With Reception
This study used the National Health Insurance Service Health examinee Sample Cohort. We selected subjects who were over the age of 60 years and who had received a newly diagnosis of hypertension (Korean Classification of Disease [KCD] codes I10–I13) from 2003 to 2006. Subjects who had previous major cardiovascular (CV) events, such as heart failure, ischemic heart disease, stroke, or end stage renal disease (ESRD) were excluded. The remaining 25,858 individuals were divided into three groups; 1) mean systolic blood pressure (SBP)
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Jiwon Seo, Sungha Park, Chan Joo Lee, Jinseub Hwang Tags: Poster Abstract Presentations Source Type: research