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Total 615 results found since Jan 2013.

Vasculitis associated with adenosine deaminase 2 deficiency: at the crossroads between Beh çet's disease and autoinflammation. A viewpoint
Reumatismo. 2023 Sep 18;75(3). doi: 10.4081/reumatismo.2023.1578.ABSTRACTAdenosine deaminase 2 deficiency (DADA2) is a rare monogenic vasculopathy caused by loss-of-function homozygous or compound heterozygous mutations in ADA2, formerly CECR1 (cat eye syndrome chromosome region 1) gene. The DADA2 phenotype is widely heterogeneous, and patients may present with fever, weight loss, livedo reticularis/racemosa, digital ischemia, cutaneous ulceration, peripheral neuropathy, abdominal pain, bowel perforation, and portal or nephrogenic hypertension. More specific manifestations include early-onset ischemic or hemorrhagic stroke...
Source: Reumatismo - September 18, 2023 Category: Rheumatology Authors: A Colangelo F Tromby G Cafaro R Gerli E Bartoloni C Perricone Source Type: research

As Wegovy jab becomes available on the NHS... Here's how the next weight-loss drug could be a PILL (and it may be cheaper with fewer side-effects)
New data from a five-year trial of Wegovy suggested it could cut the risk of a heart attack or stroke in obese people with cardiovascular disease by a fifth.
Source: the Mail online | Health - September 4, 2023 Category: Consumer Health News Source Type: news

Can This Breakfast Food Reverse Alzheimer ’ s?
I’m sure you’ve noticed how expensive eggs have gotten lately. The price has soared more than any other food in the supermarket…up 60% from one year ago.1 One reason for skyrocketing prices is the ongoing avian flu epidemic. But another reason is that demand for “nature’s perfect food” has increased substantially. And that is good news because eggs are essential for your health – including the fight against Alzheimer’s. And that means they’re worth every penny for the way they protect your brain. Two breakthrough studies back up what I’ve been telling my patients for over three decades… That ...
Source: Al Sears, MD Natural Remedies - August 25, 2023 Category: Complementary Medicine Authors: Jacob Tags: Anti-Aging Brain Health Nutrition Source Type: news

Dysphagia in Neurological Disorders
Semin Neurol DOI: 10.1055/s-0043-1771458Dysphagia is a common symptom in many neurologic disorders. Patients with oropharyngeal dysphagia present with difficulties when they start to swallow, often with coughing and choking; whereas patients with esophageal dysphagia describe the feeling that swallowed food stops in the chest. Chronic neurologic diseases such stroke, Parkinson's disease, or dementia often have dysphagia as a symptom, particularly oropharyngeal dysphagia, and the term “neurogenic dysphagia” is often used. A disruption of the sophisticated, integrated sensorimotor swallowing system is usually the main re...
Source: Seminars in Neurology - August 14, 2023 Category: Neurology Authors: El Halabi, Maan Arwani, Remy Parkman, Henry P. Tags: Review Article Source Type: research

Lauric acid provides neuroprotection against oxidative stress in mouse model of hyperglycaemic stroke
Eur J Pharmacol. 2023 Aug 10:175990. doi: 10.1016/j.ejphar.2023.175990. Online ahead of print.ABSTRACTDuring ischemic stroke, higher glucose level linked worse outcomes were reported even in patients without pre-existing diabetes. Evidence suggest that such worse stroke outcomes were mainly due to production of reactive, toxic glucose metabolites that expands oxidative damage inside the brain. As a consequence of high oxidative stress, microvasculature structures and tight junctions compromised their functionally, infarct volume expands and brain edema exacerbates. In a mouse model of ischemic stroke with induced acute hyp...
Source: European Journal of Pharmacology - August 12, 2023 Category: Drugs & Pharmacology Authors: Zaib Ali Shaheryar Mahtab Ahmad Khan Huma Hameed Syed Awais Ali Zaidi Irfan Anjum Muhammad Shafeeq Ur Rahman Source Type: research

News at a glance: A win for obesity drugs, NIH unionization roadblocks, and Mexican fireflies under threat
CONSERVATION Researchers raise alarm over threat to Mexican fireflies Scientists from the International Union for Conservation of Nature (IUCN) last week delivered a letter to the Mexican government requesting it regulate tourism centered on the threatened firefly species Photinus palaciosi . Endemic to Mexico’s Tlaxcala forests, P. palaciosi is one of the few species that glow in synchrony, offering an annual spectacle that attracts thousands of visitors during summer mating season. The letter describes how littering, artificial light, and noise interfere with the insects’ courtship and eg...
Source: ScienceNOW - August 10, 2023 Category: Science Source Type: news

News at a glance: A win for obesity drugs, a new infectious disease institute head, and Mexican fireflies under threat
CONSERVATION Researchers raise alarm over threat to Mexican fireflies Scientists from the International Union for Conservation of Nature (IUCN) last week delivered a letter to the Mexican government requesting it regulate tourism centered on the threatened firefly species Photinus palaciosi . Endemic to Mexico’s Tlaxcala forests, P. palaciosi is one of the few species that glow in synchrony, offering an annual spectacle that attracts thousands of visitors during summer mating season. The letter describes how littering, artificial light, and noise interfere with the insects’ courtship and eg...
Source: Science of Aging Knowledge Environment - August 10, 2023 Category: Geriatrics Source Type: research

Weight-loss drug Wegovy cuts risk of stroke, heart attacks, company said
Create your free profile or log in to save this article Create your free profile or log in to save this article The popular obesity drug Wegovy cuts the risk of cardiovascular events, such as heart attack and stroke, by 20%, drugmaker Novo Nordisk said Tuesday. The findings are the first to…#novonordisk #shaunalevy #neworleans #wegovy #hollylofton #nyulangonehealth #wegovyandozempic #ahip #davidallen #weight
Source: Reuters: Health - August 8, 2023 Category: Consumer Health News Source Type: news

Results of a 12-Month Randomized Controlled Trial Testing the Efficacy of the Diabetes Prevention Program Group Lifestyle Balance (DPP-GLB) for People Post Stroke (GLB-CVA)
CONCLUSIONS: Engagement in the GLB-CVA can result in weight loss and improved health for individuals who are overweight or obese following stroke. Future efforts should examine effectiveness in real-world settings and focus on knowledge translation efforts.PMID:37542523 | DOI:10.1093/abm/kaad045
Source: Annals of Behavioral Medicine - August 5, 2023 Category: Psychiatry & Psychology Authors: Simon Driver Evan McShan Chad Swank Stephanie Calhoun Megan Douglas Alexandria Suhalka Monica Bennett Librada Callender Christa Ochoa Sridevi Mukkamala Kaye Kramer Source Type: research

86-Year-Old Woman With Fever, New-Onset Dysarthria, and Ataxia
An 86-year-old woman with a medical history of hypertension, hyperlipidemia, permanent atrial fibrillation receiving anticoagulation, and chronic venous stasis causing recurrent leg cellulitis presented to the emergency department for new-onset dysarthria and imbalance, which began earlier that morning. She denied a history of stroke, chills, unintentional weight loss, diarrhea, dysuria, frequency, or recent head trauma. The patient endorsed taking her anticoagulation as prescribed without skipped doses.
Source: Mayo Clinic Proceedings - August 1, 2023 Category: Internal Medicine Authors: Nikita Jhawar, Abdallah El Sabbagh Tags: Residents ’ Clinic Source Type: research

Peripheral artery disease: Update on etiology, pathophysiology, diagnosis and treatment
Med Clin (Barc). 2023 Jul 28:S0025-7753(23)00361-5. doi: 10.1016/j.medcli.2023.06.005. Online ahead of print.ABSTRACTPeripheral artery disease (PAD) is a condition related to atherosclerosis affecting >200 million people worldwide, and it increases cardiovascular morbidity (mainly from myocardial infarction and stroke) and mortality. Indeed, PAD patients are classified as patients at very high cardiovascular risk. The most common manifestation of PAD is intermittent claudication, which is associated with reduced mobility and leg pain. Nevertheless, asymptomatic PAD is the most frequent form of PAD worldwide; therefore, ...
Source: Medicina Clinica - July 30, 2023 Category: General Medicine Authors: Dar ío Mandaglio-Collados Francisco Mar ín Jos é Miguel Rivera-Caravaca Source Type: research