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Nutrition: Vitamin D
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Total 260 results found since Jan 2013.
Vitamin D and brain health: an observational and Mendelian randomization study
CONCLUSIONS: Low vitamin D status was associated with neuroimaging outcomes and the risks of dementia and stroke even after extensive covariate adjustment. MR analyses support a causal effect of vitamin D deficiency on dementia but not on stroke risk.PMID:35451454 | DOI:10.1093/ajcn/nqac107
Source: The American Journal of Clinical Nutrition - April 22, 2022 Category: Nutrition Authors: Shreeya S Navale Anwar Mulugeta Ang Zhou David J Llewellyn Elina Hypp önen Source Type: research
Identifying factors contributing to increased susceptibility to COVID-19 risk: a systematic review of Mendelian randomization studies
ConclusionThis review summarizes modifiable factors for intervention (e.g. smoking, obesity and inflammatory factors) and proteomic signatures (e.g. OAS1 and IL-6) that could help identify drugs for treating COVID-19.
Source: International Journal of Epidemiology - April 20, 2022 Category: Epidemiology Source Type: research
Vitamin D and its possible relationship to neuroprotection in COVID-19: evidence in the literature
Curr Top Med Chem. 2022 Apr 1. doi: 10.2174/1568026622666220401140737. Online ahead of print.ABSTRACTVitamin D is a hormone involved in the regulation of important biological processes such as signal transduction, immune response, metabolic regulation and also in the nervous and vascular systems. To date, coronavirus disease 2019 (COVID-19) infection does not have a specific treatment, however various drugs have been proposed, including those that attenuate the intense inflammatory response and recently the use of vitamin D, in clinical trials, as part of the treatment of COVID-19 has provided promising results. It has bee...
Source: Current Topics in Medicinal Chemistry - April 3, 2022 Category: Chemistry Authors: Saray Quintero-Fabi án Cindy Bandala Luz Adriana Pichardo-Mac ías Itzel Jatziri Contreras-Garc ía Sa úl Gómez-Manzo Beatriz Hern ández-Ochoa Jos é Arturo Martínez-Orozco Iv án Ignacio-Mejía Noem í Cárdenas-Rodríguez Source Type: research
Association between Fok1 and TaqI polymorphisms of vitamin D receptor gene with the severity of stenosis and calcification in carotid bulb in patients with ischemic stroke
CONCLUSIONS: There may be a biological association between the FokI VDR gene and carotid bulb calcification.PMID:35091316 | DOI:10.1016/j.jocn.2022.01.009
Source: Atherosclerosis - January 29, 2022 Category: Cardiology Authors: Farzaneh Foroughinia Najmeh Morovati Anahid Safari Mehdi Dianatpour Iman Jamhiri Seyed Taghi Heydari Sedighe Hooshmandi Afshin Borhani-Haghighi Source Type: research
Mendelian randomization analysis of vitamin D in the secondary prevention of hypertensive-diabetic subjects: role of facilitating blood pressure control
ConclusionsGenetically predicted increase in Vit-D status [25(OH)D] may confer secondary protection against incident combined CVD events and myocardial infarction in a hypertensive-diabetic population where serological 25(OH)D deficiency is common, through facilitating blood pressure control.
Source: Genes and Nutrition - January 29, 2022 Category: Nutrition Source Type: research
Vitamin D supplementation and prevention of cardiovascular disease and cancer in the Finnish Vitamin D Trial-a randomized controlled trial
CONCLUSIONS: Vitamin D3 supplementation did not lower the incidence of major CVD events or invasive cancer among older adults, possibly due to sufficient vitamin D status in most participants at baseline. Clinical Trial Registry number: ClinicalTrials.gov: NCT01463813, https://clinicaltrials.gov/ct2/show/NCT01463813.PMID:34982819 | DOI:10.1093/ajcn/nqab419
Source: The American Journal of Clinical Nutrition - January 4, 2022 Category: Nutrition Authors: Jyrki K Virtanen Tarja Nurmi Antti Aro Elizabeth R Bertone-Johnson Elina Hypp önen Heikki Kr öger Christel Lamberg-Allardt JoAnn E Manson Jaakko Mursu Pekka M äntyselkä Sakari Suominen Matti Uusitupa Ari Voutilainen Tomi-Pekka Tuomainen Sari Hantunen Source Type: research
A repeated measures approach to pooled and calibrated biomarker data
Biometrics. 2021 Dec 30. doi: 10.1111/biom.13618. Online ahead of print.ABSTRACTParticipant level meta-analysis across multiple studies increases the sample size for pooled analyses, thereby improving precision in effect estimates and enabling subgroup analyses. For analyses involving biomarker measurements as an exposure of interest, investigators must first calibrate the data to address measurement variability arising from usage of different laboratories and/or assays. In practice, the calibration process involves reassaying a random subset of biospecimens from each study at a central laboratory and fitting models that r...
Source: Cancer Control - December 30, 2021 Category: Cancer & Oncology Authors: Abigail Sloan Chao Cheng Bernard Rosner Regina G Ziegler Stephanie A Smith-Warner Molin Wang Source Type: research
Research Progress on the Correlation Between Vitamin D and Neurological Disorders
Conclusion VD deficiency is very common in the population and is associated with a variety of neurological diseases. VD, a neuroactive steroid, plays an important role in the protection of the central nervous system. In contrast, stroke can cause epilepsy and varying degrees of changes in cognitive function. Furthermore, seizure and epilepsy can cause changes in cognitive function. The degree of alteration in cognitive function affects the occurrence and progression of stroke and epilepsy. Therefore, VD can be used for the comprehensive treatment of neurological diseases.PMID:34936071 | DOI:10.5137/1019-5149.JTN.34816-21.1
Source: Turkish Neurosurgery - December 22, 2021 Category: Neurosurgery Authors: Mengjie Wang Changmeng Cui Feng Jin Source Type: research
