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Nutrition: Vitamin B3

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Total 42 results found since Jan 2013.

Role of Vitamins in Cardiovascular Health: Know Your Facts - Part 1
Curr Vasc Pharmacol. 2023 Sep 12. doi: 10.2174/1570161121666230912155548. Online ahead of print.ABSTRACTCardiovascular (CV) disease (CVD) is a major cause of morbidity and mortality world-wide, thus it is important to adopt preventive interventions. Observational data demonstrating CV benefits of vitamin supplements, advanced by self-proclaimed experts have resulted in ~50% of Americans reporting the use of multivitamins for health promotion; this practice has led to a multi-billion-dollar business of the multivitamin-industry. However, the data on the extensive use of multivitamins show no consistent benefit for CVD preve...
Source: Current Vascular Pharmacology - September 13, 2023 Category: Drugs & Pharmacology Authors: Antonis A Manolis Theodora A Manolis Helen Melita Antonis S Manolis Source Type: research

Role of Vitamins in Cardiovascular Health: Know Your Facts-Part 2
Curr Vasc Pharmacol. 2023 Sep 11. doi: 10.2174/1570161121666230911115725. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is a major cause of morbidity/mortality world-wide, hence preventive interventions are crucial. Observational data showing beneficial CV-effects of vitamin supplements, promoted by self-proclaimed experts, have led to ~50% of Americans using multivitamins; this practice has culminated into a multi-billion-dollar business. However, robust evidence is lacking, and certain vitamins might incur harm. This two-part review focuses on the attributes or concerns about specific vitamin consumption on ...
Source: Atherosclerosis - September 11, 2023 Category: Cardiology Authors: Antonis A Manolis Theodora A Manolis Helen Melita Antonis S Manolis Source Type: research

Neuroprotection of NAD+ and NBP against ischemia/reperfusion brain injury is associated with restoration of sirtuin-regulated metabolic homeostasis
Conclusions: These results confirmed the protective effects of NAD+ and NBP on cerebral ischemic injury. NBP and NAD+ showed similar antioxidant effects, while NAD+ had better ability in restoring energy metabolism, possibly through upregulating the activity of SIRT1 and SIRT3. The protection provided by NBP against cerebral ischemia/reperfusion may be achieved through SIRT1.
Source: Frontiers in Pharmacology - March 28, 2023 Category: Drugs & Pharmacology Source Type: research

Here ’s an Alternative to Statins for Lowering Cholesterol
Statins have revolutionized heart disease by lowering cholesterol effectively—by up to 50% or more. But anywhere from 7% to 29% of people who take them may be more susceptible to its side effects, which include weakening of muscles and pain, and decide they can’t tolerate them. In a recent study published in JAMA Network Open, for example, researchers at Brigham and Women’s Hospital reported that more than 20% of patients seen at the hospital from 2000 to 2018 who were recommended to take statins refused to take them, and those who refused took three times as long to lower their LDL cholesterol to target ...
Source: TIME: Health - March 4, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized healthscienceclimate heart health Source Type: news

What to Know if Your Doctor Put You on Statins to Lower Cholesterol
High cholesterol is a prime example of having too much of a good thing. Our bodies naturally make this substance in the liver and then transport it throughout the body for multiple functions, including hormone regulation, cell tissue regeneration, and vitamin absorption. When the system is working well, cholesterol can boost overall health. But when a certain type called low-density lipoprotein—LDL, sometimes dubbed the “bad” kind—is overproduced, not only does it block the “good” kind called high-density lipoprotein (HDL), but it can also begin to accumulate in the arteries and form thi...
Source: TIME: Health - January 25, 2023 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized healthscienceclimate heart health Source Type: news

The 5 Best Ways to Control High Cholesterol, According to People With the Condition
There are a variety of factors that influence cardiovascular risk—but cholesterol is one of the first things that doctors pay attention to. Having high levels of low-density lipoprotein (LDL) cholesterol is “definitely a variable we try to manage, because it’s been shown to be problematic for heart health,” says Dr. Adriana Quinones-Camacho, a cardiologist at NYU Langone Health. Though it’s often called the “bad” kind of cholesterol, LDL cholesterol makes up most of your body’s cholesterol stores. That means it’s not a villain on its own, but when levels start creeping ...
Source: TIME: Health - January 18, 2023 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized healthscienceclimate heart health Source Type: news

The HF-AF ENERGY Trial: Nicotinamide Riboside for the Treatment of Atrial Fibrillation in Heart Failure Patients
ConclusionThe HF-AF ENERGY trial investigates the cardioprotective effects of NR on AF burden and whether NR normalizes blood-based mitochondrial function markers and energy metabolites of the NAD metabolome in ischemic heart disease patients diagnosed with AF. The study outcomes elucidate whether NAD+ metabolism can be used as a future therapy for HF patients with AF.
Source: Cardiovascular Drugs and Therapy - October 13, 2022 Category: Cardiology Source Type: research

Associations of Dietary Intakes of Vitamins B1 and B3 with Risk of Mortality from Cardiovascular Disease among Japanese Men and Women: the Japan Collaborative Cohort Study
CONCLUSIONS: Higher dietary intakes of vitamins B1 and B3 were inversely associated with mortality from ischemic heart disease and a higher dietary intake of vitamin B1 was inversely associated with a reduced risk of mortality from heart failure among Japanese men and women.PMID:35466893 | DOI:10.1017/S0007114522001209
Source: The British Journal of Nutrition - April 25, 2022 Category: Nutrition Authors: Chengyao Tang Ehab S Eshak Kokoro Shirai Akiko Tamakoshi Hiroyasu Iso Source Type: research

Long-Term Abnormalities of Lipid Profile After a Single Episode of Sepsis
Conclusions: Our study suggests that persistent derangements of lipid profile components for up to two years after sepsis may be associated with altered risk of atherosclerosis-related events among sepsis survivors.PMID:34869619 | PMC:PMC8634493 | DOI:10.3389/fcvm.2021.674248
Source: Atherosclerosis - December 6, 2021 Category: Cardiology Authors: Nicholas Felici Da Liu Josh Maret Mariana Restrepo Yuliya Borovskiy Jihane Hajj Wesley Chung Krzysztof Laudanski Source Type: research