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Quality and safety in the literature: July 2023
Healthcare quality and safety span multiple topics across the spectrum of academic and clinical disciplines. Keeping abreast of the rapidly growing body of work can be challenging. In this series, we provide succinct summaries of selected relevant studies published in the last several months. Some articles will focus on a particular theme, whereas others will highlight unique publications from high-impact medical journals. Key points Despite increased attention to patient safety over the last several decades, adverse events continue to be common in hospitalised patients, occurring in 23.6% of admissions studied. N Engl J M...
Source: Quality and Safety in Health Care - June 19, 2023 Category: Health Management Authors: Youssef, C., Houchens, N., Gupta, A. Tags: Quality & amp; safety in the literature Source Type: research

Genetic associations between miR ‑200bT & gt;C and miR ‑495A & gt;C polymorphisms and hypertension susceptibility
Exp Ther Med. 2023 May 31;26(1):353. doi: 10.3892/etm.2023.12052. eCollection 2023 Jul.ABSTRACTAlthough microRNA (miRNA)-mediated functions and gene expression regulation are involved in the susceptibility to vascular diseases, the potential effect of miRNA polymorphisms on the susceptibility of patients to hypertension (HTN) remains to be sufficiently elucidated. Therefore, the present study aimed to identify the potential association between miRNA (miR)-200bT>C (rs7549819) and miR-495A>C (rs2281611) polymorphisms, which may be implicated in stroke and vascular pathogenesis, and the susceptibility to HTN and relevan...
Source: Experimental and Therapeutic Medicine - June 16, 2023 Category: General Medicine Authors: Youngmi Choi Seung-Ho Hong Source Type: research

Computed tomography angiography-based radiomics model for predicting carotid atherosclerotic plaque vulnerability
This study aimed to identify radiomic features associated with the neovascularization of CAP and construct a prediction model for CAP vulnerability based on radiomic features. CTA data and clinical data of patients with CAPs who underwent CTA and CEUS between January 2018 and December 2021 in Beijing Hospital were retrospectively collected. The data were divided into a training cohort and a testing cohort using a 7:3 split. According to the examination of CEUS, CAPs were dichotomized into vulnerable and stable groups. 3D Slicer software was used to delineate the region of interest in CTA images, and the Pyradiomics package...
Source: Frontiers in Neurology - June 16, 2023 Category: Neurology Source Type: research

In-hospital recurrence and functional outcome between ischemic stroke caused by intracranial arterial dissection and intracranial atherosclerosis: Retrospective cohort study of the nationwide multicenter registry
This study aimed to determine the association of ICAD and ICAS with in-hospital recurrence and prognosis and compare their background and clinical findings.
Source: Journal of Stroke and Cerebrovascular Diseases - June 16, 2023 Category: Neurology Authors: Gaku Fujiwara, Hideki Oka, Akihiro Fujii Source Type: research

I was pronounced 'DEAD' for three minutes after suffering heatstroke
Jade, 34, said she was dead for around three minutes after suffering from heat stroke. She claimed St Vincent's Hospital, Wisconsin, revived with a defibrillator.
Source: the Mail online | Health - June 13, 2023 Category: Consumer Health News Source Type: news

P2Y12 inhibitor monotherapy versus dual antiplatelet therapy in patients with acute coronary syndromes undergoing coronary stenting: rationale and design of the NEOMINDSET Trial
EuroIntervention. 2023 Jun 12:EIJ-D-23-00125. doi: 10.4244/EIJ-D-23-00125. Online ahead of print.ABSTRACTDual antiplatelet therapy (DAPT) is currently the standard of care after percutaneous coronary intervention (PCI). Recent studies suggest that reducing DAPT to 1-3 months followed by an aspirin-free single antiplatelet therapy (SAPT) strategy with a potent P2Y12 inhibitor is safe and associated with less bleeding. However, to date, no randomised trial has tested the impact of initiating SAPT immediately after PCI, particularly in patients with acute coronary syndromes (ACS). NEOMINDSET is a multicentre, randomised, open...
Source: EuroIntervention - June 12, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Patricia O Guimar ães Marcelo Franken Caio A M Tavares Fabio S Silveira Murillo O Antunes Ricardo R Bergo Rodrigo M Joaquim Jessica C S Hirai Pedro B Andrade Fabio G Pitta Jos é Mariani Bruno R Nascimento Jo ão E T de Paula Marcos S Silveira Tiberio A Source Type: research

Incidental Finding of Arteria Lusoria in COVID-19 Patient with Aortic Thrombus Complicated by Recurrent Limb Ischemia
We report the case of a 64-year-old woman with recent severe acute respiratory syndrome coronavirus 2 pneumonia who was admitted to the hospital due to a giant floating thrombus in the ascending aorta with multiple ischemic events. Aortic computed tomography angiogram revealed an aberrant right subclavian artery associated with bicarotid trunk that might have protected carotid arteries from embol migration. Thrombosis is a rare clinical presentation in coronavirus disease 2019 infection but with serious complications that must be kept in mind to detect and avoid morbidities like ischemic stroke. [...] Thieme Medical Publis...
Source: International Journal of Angiology - June 12, 2023 Category: Cardiology Authors: Khedija, Soumer Nadia, Azabou Houcine, Horchani Mouna, Bousnina Amine, Jemel Tags: Case Report Source Type: research

Impact of the COVID-19 pandemic on visits to the hospital emergency service in two hospitals in Spain, from March 14, 2020 to June 21, 2020
This study will describe trends in the use of emergency departments before and after the Spanish State of Alarm, especially in pathologies not directly related to this infection. A cross-sectional study was conducted of all visits to the emergency departments in two third-level hospitals in two Spanish communities during the Spanish State of Alarm, compared with the same period of the previous year. The variables collected included the day of the week, the time of the visit, the duration of the visit, the final destination of the patients (home, admission to a conventional hospitalization ward, admission to the intensive c...
Source: Internal and Emergency Medicine - June 12, 2023 Category: Emergency Medicine Source Type: research

Septic Shock From Pan-Spinal Epidural Abscess Attributed to Recent Acupuncture and Trigger Point Injections for Acute Lower Back Pain in a Previously Undiagnosed Diabetic Patient: A Case Report
We report the case of a 60-year-old woman with undiagnosed diabetes mellitus who presented to the hospital with a complaint of progressive altered mental status for the past two days. Eight days prior to presentation, the patient tripped over a pillow at home and developed mildly nagging, acute lower back pain. Upon the recommendation of her friends, she underwent two sessions of acupuncture around the lumbar area on days six and five prior to being brought to the hospital. She also saw her primary care physician on day three prior to presentation, who performed a history and physical examination and, after feeling that sh...
Source: Pain Physician - June 9, 2023 Category: Anesthesiology Authors: Shaheryar Usman Faraz Badar Carlos Collado Andrew Weber Alan Kaell Source Type: research