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Total 9563 results found since Jan 2013.

Study on self-management of real-time and individualized support in stroke patients based on resilience: a protocol for a randomized controlled trial
The transitional period from hospital to home is vital for stroke patients, but it poses serious challenges. Good self-management ability can optimize disease outcomes. However, stroke patients in China have a...
Source: Trials - August 3, 2023 Category: General Medicine Authors: N. Jiang, Y. Xv, X. Sun, L. Feng, Y. B. Wang and X. L. Jiang Tags: Study protocol Source Type: research

Will unpredictable side effects dim the promise of new Alzheimer ’s drugs?
A sea change is underway in the treatment of Alzheimer’s disease, where for the first time a drug that targets the disease’s pathology and clearly slows cognitive decline has hit the U.S. market. A related therapy will likely be approved in the coming months. As many neurologists, patients, and brain scientists celebrate, they’re also nervously eyeing complications from treatment: brain swelling and bleeding, which in clinical trials affected up to about one-third of patients and ranged from asymptomatic to fatal. The side effect—amyloid-related imaging abnormalities, or ARIA—remains mysterious. “We don’...
Source: Science of Aging Knowledge Environment - August 2, 2023 Category: Geriatrics Source Type: research

Impact of the COVID-19 Pandemic on Admission and Mortality Among Patients With Severe Emergency Diseases at Emergency Departments in Korea in 2020: Registry Data From the National Emergency Department Information System
J Korean Med Sci. 2023 Jul 31;38(30):e243. doi: 10.3346/jkms.2023.38.e243.ABSTRACTWe aimed to investigate the impact of the coronavirus disease 2019 (COVID-19) pandemic on admissions of patients with acute myocardial infarction, stroke, and severe trauma, and their excess mortality in emergency departments (EDs) in South Korea using registry data from the National Emergency Department Information System (NEDIS) for patients attending EDs of regional and local emergency medical centers. During the outbreak period of 2020, there were 350,698 ED visits, which was lower than the total in 2019 (392,627 visits). Multiple logisti...
Source: J Korean Med Sci - August 1, 2023 Category: General Medicine Authors: Sun Kyoung Na Jeung-Hee Kim Weon-Young Lee Mi Ra Oh Source Type: research

Associations between early in-hospital medications and the development of delirium in patients with stroke
Patients hospitalized with stroke develop delirium at higher rates than general hospitalized patients. While several medications are associated with existing delirium, it is unknown whether early medication exposures are associated with subsequent delirium in patients with stroke. Additionally, it is unknown whether delirium identification is associated with changes in the prescription of these medications.
Source: Journal of Stroke and Cerebrovascular Diseases - August 1, 2023 Category: Neurology Authors: Sophia L. Ryan, Xiu Liu, Vanessa McKenna, Manohar Ghanta, Carlos Muniz, Rachel Renwick, M. Brandon Westover, Eyal Y. Kimchi Source Type: research

Bedtime versus morning use of antihypertensives in frail continuing care residents (BedMed-Frail): protocol for a prospective, randomised, open-label, blinded end-point pragmatic trial
Introduction BedMed-Frail explores risks and benefits of switching antihypertensives from morning to bedtime in a frail population at greater risk of hypotensive adverse effects. Methods and analysis Design: Prospective parallel randomised, open-label, blinded end-point trial. Participants: Hypertensive continuing care residents, in either long-term care or supportive living, who are free from glaucoma, and using ≥1 once daily antihypertensive. Setting: 16 volunteer continuing care facilities in Alberta, Canada, with eligible residents identified using electronic health claims data. Intervention: All non-opted out elig...
Source: BMJ Open - August 1, 2023 Category: General Medicine Authors: Garrison, S. R., Youngson, E., Perry, D. A., Campbell, F. N., Kolber, M. R., Korownyk, C., Allan, G. M., Green, L., Bakal, J. Tags: Open access, Cardiovascular medicine Source Type: research

One-Year Outcome of Patients with Chest Pain in the Rule-Out Group According to the 0-Hour/1-Hour Algorithm
Int Heart J. 2023;64(4):590-595. doi: 10.1536/ihj.23-076.ABSTRACTThe European Society of Cardiology recommends the 0/1-hour algorithm for risk stratification of patients with suspected non-ST-elevation myocardial infarction as class I, level B; however, there are few reports on the long-term prognosis, resulting in a rule-out group. We aimed to determine whether implementation of the 0-hour/1-hour algorithm is safe and effective in emergency department (ED) patients with possible acute coronary syndrome (ACS) through a 1-year follow-up period. Our study analyzed the 1-year follow-up data from a prospective pre-post study o...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Shun Sasaki Kenji Inoue Masayuki Shiozaki Chien-Chang Lee Shuo-Ju Chiang Satoru Suwa Kentaro Fukuda Masaru Hiki Naozumi Kubota Hiroshi Tamura Manabu Sugita Masataka Sumiyoshi Tohru Minamino Source Type: research